Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   EQH38_RS01840 Genome accession   NZ_CP035242
Coordinates   339595..339999 (+) Length   134 a.a.
NCBI ID   WP_223842268.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901947     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 334595..344999
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH38_RS01815 (EQH38_01920) - 335001..336131 (+) 1131 WP_000885068.1 N-acetyldiaminopimelate deacetylase -
  EQH38_RS01820 (EQH38_01925) - 336143..336682 (+) 540 WP_054424784.1 5-formyltetrahydrofolate cyclo-ligase -
  EQH38_RS01825 (EQH38_01930) - 336666..337343 (+) 678 WP_000658495.1 rhomboid family intramembrane serine protease -
  EQH38_RS01830 (EQH38_01935) galU 337410..338309 (-) 900 WP_000202218.1 UTP--glucose-1-phosphate uridylyltransferase GalU -
  EQH38_RS01835 (EQH38_01940) - 338331..339347 (-) 1017 WP_054366240.1 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase -
  EQH38_RS01840 (EQH38_01945) comR 339595..339999 (+) 405 WP_223842268.1 helix-turn-helix transcriptional regulator Regulator
  EQH38_RS01845 (EQH38_01950) - 340114..340566 (-) 453 Protein_376 transposase -
  EQH38_RS01850 (EQH38_01955) phoU 340607..341257 (-) 651 WP_001245781.1 phosphate signaling complex protein PhoU -
  EQH38_RS01855 (EQH38_01960) pstB 341272..342024 (-) 753 WP_000536449.1 phosphate ABC transporter ATP-binding protein PstB -
  EQH38_RS01860 (EQH38_01965) pstA 342026..342841 (-) 816 WP_000049768.1 phosphate ABC transporter permease PstA -
  EQH38_RS01865 (EQH38_01970) pstC 342834..343697 (-) 864 WP_000595182.1 phosphate ABC transporter permease subunit PstC -
  EQH38_RS01870 (EQH38_01975) - 343815..344690 (-) 876 WP_000669493.1 substrate-binding domain-containing protein -

Sequence

Protein


Download         Length: 134 a.a.        Molecular weight: 16261.66 Da        Isoelectric Point: 4.5242

>NTDB_id=295599 EQH38_RS01840 WP_223842268.1 339595..339999(+) (comR) [Streptococcus pneumoniae strain TVO_1901947]
MAKKISRSEFCGDESELSIRQLIRIENGESRPILTKLKYIAERLEVEDYKLMPSYIELDKEYLELKYFLMRTPTYEDETI
TQKKESVFDKIFEEYYDRLPEEERFIIPNYSYLALTNYTVQKLPEKLVEILSFW

Nucleotide


Download         Length: 405 bp        

>NTDB_id=295599 EQH38_RS01840 WP_223842268.1 339595..339999(+) (comR) [Streptococcus pneumoniae strain TVO_1901947]
TTGGCTAAAAAAATCAGTCGTTCAGAATTTTGTGGTGATGAGTCTGAATTAAGTATCCGTCAATTAATTAGAATTGAAAA
TGGAGAATCCAGACCAATACTAACAAAGTTAAAATATATTGCTGAACGTTTGGAGGTTGAAGATTACAAGTTGATGCCAA
GTTATATAGAGTTGGATAAGGAATACCTAGAATTGAAGTATTTCTTGATGAGGACTCCTACATACGAAGATGAAACTATC
ACCCAAAAGAAAGAGAGTGTTTTTGATAAGATTTTTGAAGAGTATTATGATAGGCTACCTGAGGAAGAAAGATTTATCAT
CCCAAATTATTCATATCTGGCACTAACGAACTACACAGTTCAAAAATTACCAGAAAAGCTAGTTGAAATACTGTCCTTCT
GGTGA

Domains

Predicted by InterProScan.

ComR tetratricopeptide (ComR_TPR)

(60-107)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus pyogenes MGAS8232

54.63

80.597

0.44
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

54.717

79.104

0.433
  comR Streptococcus pyogenes MGAS315

52.778

80.597

0.425
  comR Streptococcus mutans UA159

50

80.597

0.403
  comR/comR1 Streptococcus sobrinus strain NIDR 6715-7

48.039

76.119

0.366
  comR Streptococcus suis P1/7

46.226

79.104

0.366
  comR Streptococcus suis 05ZYH33

46.226

79.104

0.366