Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   EQZ01_RS21275 Genome accession   NZ_CP035231
Coordinates   4070162..4071364 (-) Length   400 a.a.
NCBI ID   WP_015250812.1    Uniprot ID   A0ABU0V6N7
Organism   Bacillus subtilis strain SRCM103571     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4065162..4076364
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQZ01_RS21250 (EQZ01_21250) - 4066103..4067569 (-) 1467 WP_046381472.1 HAMP domain-containing sensor histidine kinase -
  EQZ01_RS21255 (EQZ01_21255) - 4067566..4068249 (-) 684 WP_024573086.1 response regulator transcription factor -
  EQZ01_RS21260 (EQZ01_21260) - 4068461..4069360 (+) 900 WP_128738533.1 PepSY domain-containing protein -
  EQZ01_RS21265 (EQZ01_21265) - 4069521..4070021 (+) 501 WP_128738535.1 PepSY domain-containing protein -
  EQZ01_RS21270 (EQZ01_21270) - 4070025..4070142 (-) 118 Protein_4121 hypothetical protein -
  EQZ01_RS21275 (EQZ01_21275) htrA 4070162..4071364 (-) 1203 WP_015250812.1 serine protease HtrC Regulator
  EQZ01_RS21280 (EQZ01_21280) vicX 4071446..4072240 (-) 795 WP_003226939.1 MBL fold metallo-hydrolase Regulator
  EQZ01_RS21285 (EQZ01_21285) walI 4072262..4073104 (-) 843 WP_029318542.1 WalRK two-component regulatory system regulator WalI -
  EQZ01_RS21290 (EQZ01_21290) walH 4073091..4074458 (-) 1368 WP_128738537.1 WalRK two-component regulatory system regulator WalH -
  EQZ01_RS21295 (EQZ01_21295) walK 4074448..4076283 (-) 1836 WP_009968432.1 cell wall metabolism sensor histidine kinase WalK -

Sequence

Protein


Download         Length: 400 a.a.        Molecular weight: 42756.50 Da        Isoelectric Point: 5.5340

>NTDB_id=294754 EQZ01_RS21275 WP_015250812.1 4070162..4071364(-) (htrA) [Bacillus subtilis strain SRCM103571]
MVDYEREEEHTTPEQPKRSKKGYFLSSLIGVIVGAVLMAFIMPYLSNEGLDTGALDQQQNNNGRESIRTVNVSVNNTVTK
IVSNVSPAVVGVVNIQKSDIRGESGEAGSGSGVIYKKNDHSAYVVTNHHVIEGASQIEISLKDGSRVSADLVGSDQLMDL
AVLRVKSDKIKAVADFGNSDKVKSGEPVIAIGNPLGLEFAGSVTQGVISGTERAIPVDSNGDGQPDWNAEVLQTDAAINP
GNSGGALLNMDGKVIGINSMKIAESAVEGIGLSIPSKLVIPVIEDLERYGKVKRPFLGIEMKSLSDIASYHWDETLKLPK
NVTNGAVVMGVDAFSPAGKAGLKELDVITEFDGYKVNDIVDLRKRLYQKKVGDRVKVKFYRGGKEKSVDIKLSSADQLGS

Nucleotide


Download         Length: 1203 bp        

>NTDB_id=294754 EQZ01_RS21275 WP_015250812.1 4070162..4071364(-) (htrA) [Bacillus subtilis strain SRCM103571]
ATGGTGGATTACGAACGTGAGGAAGAACATACTACTCCTGAACAGCCAAAGAGAAGCAAAAAAGGATATTTTCTTTCAAG
CCTGATTGGTGTGATTGTCGGTGCCGTATTAATGGCGTTTATCATGCCGTACCTTTCAAATGAAGGGCTAGATACAGGCG
CCTTAGATCAGCAGCAGAACAATAACGGACGGGAATCAATCAGGACGGTGAATGTCAGTGTCAACAATACGGTCACCAAG
ATTGTCAGCAATGTGTCGCCCGCCGTTGTGGGTGTGGTGAACATCCAAAAATCAGATATACGGGGAGAGAGCGGCGAGGC
TGGGAGCGGCTCTGGCGTCATCTATAAGAAAAATGACCATTCCGCTTATGTCGTGACCAACCATCATGTCATCGAAGGCG
CTTCCCAAATTGAAATCAGCTTGAAAGACGGCTCACGTGTATCAGCTGATCTTGTCGGCAGCGACCAGCTGATGGACCTT
GCCGTTTTACGGGTGAAAAGCGATAAGATTAAAGCAGTCGCCGATTTCGGAAATTCAGATAAAGTGAAGTCTGGGGAGCC
GGTTATCGCGATTGGGAACCCGTTAGGCCTTGAGTTTGCAGGCTCTGTCACACAAGGCGTCATCTCAGGTACGGAGAGGG
CAATCCCAGTGGATTCAAACGGTGATGGACAGCCTGACTGGAACGCAGAAGTCCTGCAAACAGATGCGGCCATTAACCCT
GGGAACAGCGGCGGTGCTTTGTTAAATATGGATGGGAAGGTCATTGGCATCAATTCAATGAAAATTGCCGAGTCGGCGGT
TGAAGGGATTGGCCTGTCGATTCCATCTAAGCTCGTGATCCCTGTGATAGAGGATTTAGAGAGATACGGAAAGGTCAAAC
GCCCGTTCCTTGGCATTGAGATGAAATCGCTAAGCGACATCGCAAGCTATCATTGGGATGAAACATTGAAGCTTCCTAAG
AATGTCACCAATGGAGCGGTTGTGATGGGTGTAGACGCCTTTTCACCTGCCGGAAAAGCGGGGCTGAAGGAACTGGATGT
CATCACGGAATTTGACGGATACAAAGTAAATGATATTGTTGACCTGCGAAAACGGCTTTATCAGAAAAAAGTCGGTGACC
GGGTGAAGGTGAAGTTTTACCGCGGCGGAAAAGAAAAATCTGTAGACATCAAGCTGTCCTCTGCAGACCAATTAGGCAGT
TAA

Domains

Predicted by InterProScan.

PDZ domain (PDZ_2)

(295-392)

Peptidase family M50 (Peptidase_M50)

(196-395)

Trypsin-like peptidase domain (Trypsin_2)

(110-257)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

43.829

99.25

0.435
  htrA Streptococcus gordonii str. Challis substr. CH1

41.791

100

0.42
  htrA Streptococcus mitis NCTC 12261

43.005

96.5

0.415
  htrA Streptococcus pneumoniae TIGR4

45.758

82.5

0.378
  htrA Streptococcus pneumoniae D39

45.758

82.5

0.378
  htrA Streptococcus pneumoniae Rx1

45.758

82.5

0.378
  htrA Streptococcus pneumoniae R6

45.758

82.5

0.378