Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   EQW70_RS21640 Genome accession   NZ_CP035226
Coordinates   4134979..4136181 (-) Length   400 a.a.
NCBI ID   WP_106610979.1    Uniprot ID   -
Organism   Bacillus subtilis strain SRCM103517     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4129979..4141181
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQW70_RS21620 (EQW70_21620) rocE 4130216..4131619 (-) 1404 WP_032730280.1 amino acid permease -
  EQW70_RS21625 (EQW70_21625) rocD 4131842..4133047 (-) 1206 WP_024571526.1 ornithine aminotransferase -
  EQW70_RS21630 (EQW70_21630) rocR 4133288..4134673 (+) 1386 WP_128740891.1 arginine utilization regulatory protein RocR -
  EQW70_RS21635 (EQW70_21635) - 4134663..4134806 (-) 144 Protein_4201 ATP-binding protein -
  EQW70_RS21640 (EQW70_21640) htrA 4134979..4136181 (-) 1203 WP_106610979.1 serine protease HtrC Regulator
  EQW70_RS21645 (EQW70_21645) vicX 4136263..4137057 (-) 795 WP_021481078.1 MBL fold metallo-hydrolase Regulator
  EQW70_RS21650 (EQW70_21650) walI 4137079..4137921 (-) 843 WP_003244037.1 WalRK two-component regulatory system regulator WalI -
  EQW70_RS21655 (EQW70_21655) walH 4137908..4139275 (-) 1368 WP_032722849.1 WalRK two-component regulatory system regulator WalH -
  EQW70_RS21660 (EQW70_21660) walK 4139265..4141100 (-) 1836 WP_009968432.1 cell wall metabolism sensor histidine kinase WalK -

Sequence

Protein


Download         Length: 400 a.a.        Molecular weight: 42783.56 Da        Isoelectric Point: 5.5317

>NTDB_id=294305 EQW70_RS21640 WP_106610979.1 4134979..4136181(-) (htrA) [Bacillus subtilis strain SRCM103517]
MVDYEREEEHTTPEQPKRSKKGYFLSSLIGVIVGAVLMAFIMPYLSNEGLDTGALDQQQNNNGRESIRTVNVSVNNAVTK
IVSNVSPAVVGVVNIQKSDIWGESGEAGSGSGVIYKKNDHSAYVVTNHHVIEGASQIEISLKDGSRISAELVGSDQLMDL
AVLRVKSNKIKAVADFGNSDKVKSGEPVIAIGNPLGLEFAGSVTQGVISGTERAIPVDSNGDGQPDWNAEVLQTDAAINP
GNSGGALLNMDGKVIGINSMKIAESAVEGIGLSIPSKLVIPVIEDLERYGKVKRPFLGIEMKSLSDIASYHWDETLKLPK
NVTNGAVVMGVDAFSPAGKAGLKELDVITEFDGYKVNDIVDLRKRLYQKKVGDRVKVKFYRGGKEKSVDIKLSSADQLGS

Nucleotide


Download         Length: 1203 bp        

>NTDB_id=294305 EQW70_RS21640 WP_106610979.1 4134979..4136181(-) (htrA) [Bacillus subtilis strain SRCM103517]
ATGGTGGATTACGAACGTGAGGAAGAACATACTACTCCTGAACAGCCAAAGAGAAGCAAAAAAGGATATTTTCTTTCGAG
TCTGATTGGCGTGATTGTCGGTGCCGTATTAATGGCGTTTATCATGCCGTACCTTTCAAATGAAGGGCTGGATACAGGCG
CCTTAGATCAGCAGCAAAACAACAATGGCCGGGAATCAATCAGGACGGTAAATGTCAGTGTCAACAATGCCGTCACCAAG
ATTGTCAGCAATGTGTCGCCCGCCGTTGTCGGTGTTGTGAACATCCAAAAATCAGATATTTGGGGAGAGAGCGGCGAGGC
TGGAAGCGGCTCTGGCGTCATCTATAAGAAAAATGACCATTCCGCTTATGTCGTGACCAACCATCATGTCATCGAAGGCG
CTTCCCAAATTGAAATCAGCTTGAAAGACGGTTCACGCATATCAGCTGAACTTGTCGGCAGCGACCAGCTGATGGACCTT
GCCGTTTTACGGGTGAAAAGCAATAAAATTAAAGCAGTCGCAGATTTCGGAAATTCAGATAAAGTGAAGTCTGGCGAGCC
GGTTATTGCGATCGGGAATCCGTTAGGCCTTGAGTTTGCAGGCTCTGTCACACAAGGCGTCATCTCAGGTACGGAGAGGG
CGATCCCAGTGGATTCAAACGGTGATGGACAGCCTGACTGGAACGCAGAAGTCCTGCAAACAGATGCGGCCATTAACCCT
GGGAACAGCGGCGGTGCTTTGTTAAATATGGATGGGAAGGTCATTGGCATCAATTCAATGAAAATTGCCGAGTCGGCGGT
TGAAGGGATTGGCCTGTCGATTCCATCTAAGCTCGTGATCCCTGTGATAGAGGATTTAGAGAGATACGGAAAGGTCAAAC
GCCCGTTCCTTGGCATTGAGATGAAATCGCTAAGTGACATCGCAAGCTATCATTGGGATGAAACATTAAAGCTTCCTAAG
AACGTCACCAATGGAGCGGTTGTGATGGGTGTAGACGCCTTTTCACCTGCCGGAAAAGCGGGGCTGAAGGAACTGGATGT
CATCACGGAATTTGACGGATACAAAGTAAATGATATTGTTGACCTGCGAAAACGGCTTTATCAGAAAAAAGTCGGTGACC
GGGTGAAGGTGAAGTTTTACCGCGGCGGAAAAGAAAAATCTGTTGACATCAAGCTGTCGTCCGCAGACCAATTAGGCAGT
TAA

Domains

Predicted by InterProScan.

PDZ domain (PDZ_2)

(295-392)

Trypsin-like peptidase domain (Trypsin_2)

(110-257)

Peptidase family M50 (Peptidase_M50)

(199-395)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

43.577

99.25

0.433
  htrA Streptococcus gordonii str. Challis substr. CH1

41.294

100

0.415
  htrA Streptococcus mitis NCTC 12261

43.005

96.5

0.415
  htrA Streptococcus pneumoniae TIGR4

45.152

82.5

0.373
  htrA Streptococcus pneumoniae D39

45.152

82.5

0.373
  htrA Streptococcus pneumoniae Rx1

45.152

82.5

0.373
  htrA Streptococcus pneumoniae R6

45.152

82.5

0.373