Detailed information NTG0293190

Bioinformatically predicted

Overview

• Name: comR/comR2
• Type: Regulator
• Locus tag: DK182_RS00265
• Genome accession: NZ_CP029491
• Coordinates: 38716..39618 (+)
• Length: 300 a.a.
• NCBI ID: WP_109833386.1
• Uniprot ID: -
• Organism: Streptococcus sobrinus strain 10919
• Function: require for natural transformation (predicted from homology) Unclear

Genomic Context

Location: 33716..44618

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DK182_RS00235 (DK181_00235)	-	33752..33886 (+)	135	WP_255264604.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
DK182_RS10735	-	33916..34044 (+)	129	WP_019768929.1	hypothetical protein	-
DK182_RS10485	-	34099..34242 (+)	144	WP_019785178.1	hypothetical protein	-
DK182_RS00240 (DK181_00240)	-	34504..35325 (+)	822	WP_109833384.1	ABC transporter ATP-binding protein	-
DK182_RS00245 (DK181_00245)	-	35315..36034 (+)	720	WP_109833385.1	hypothetical protein	-
DK182_RS10740	-	36276..36404 (+)	129	WP_019768926.1	hypothetical protein	-
DK182_RS00250 (DK181_00250)	-	36535..36765 (+)	231	WP_002959611.1	hypothetical protein	-
DK182_RS00255 (DK181_00255)	-	37029..38366 (+)	1338	WP_019768925.1	hypothetical protein	-
DK182_RS00260 (DK181_00260)	-	38392..38550 (+)	159	WP_002959605.1	bacteriocin	-
DK182_RS00265 (DK181_00265)	comR/comR2	38716..39618 (+)	903	WP_109833386.1	helix-turn-helix domain-containing protein	Regulator
DK182_RS00270 (DK181_00270)	-	39748..40620 (-)	873	WP_002959599.1	helix-turn-helix domain-containing protein	-
DK182_RS00275 (DK181_00275)	-	40939..41697 (+)	759	WP_019768919.1	ABC transporter ATP-binding protein	-
DK182_RS00280 (DK181_00280)	-	41700..44009 (+)	2310	WP_109833387.1	ABC transporter permease	-

Sequence

Protein

• Length: 300 a.a.
• Molecular weight: 35719.28 Da
• Isoelectric Point: 5.3796

>NTDB_id=293190 DK182_RS00265 WP_109833386.1 38716..39618(+) (comR/comR2) [Streptococcus sobrinus strain 10919]
MTIKADLGRRIKAERNRKKISQSSFCGDEEKLTIRQLQRIEHGQSLPTLEKLEFIADRLDIKMSDLLEGRDIQLPDDYWE
MKARIVKFPTYAEKERIQRKLDLINEVLVKYFDRLPEDELLFLDLSENILDRMHDKRIPNIEEIYDDAFEQVLKKKTFTF
NDYLYLGYFLQKCRNEASYDRKIFKQIEQKLLQQELSSDEFYNIEFLVAVMDVAAVYAFHDDYKDIMPLLKKIHWIIEQA
QLHTYKAGVLELEAKYYVKIAKDKDRAKKLYQQALKLGEILEDPAIIADIKMEMKNDGIE

Nucleotide

• Length: 903 bp

>NTDB_id=293190 DK182_RS00265 WP_109833386.1 38716..39618(+) (comR/comR2) [Streptococcus sobrinus strain 10919]
ATGACAATAAAAGCAGATTTGGGACGACGGATTAAGGCCGAAAGAAACCGGAAAAAAATATCGCAGAGTTCATTTTGCGG
GGACGAAGAAAAGTTAACGATTCGTCAGTTGCAGCGGATTGAGCATGGCCAATCCCTACCAACTCTAGAAAAGTTGGAAT
TTATCGCTGATCGTTTGGACATTAAAATGTCTGACCTTCTGGAAGGTAGGGATATCCAATTACCGGATGACTATTGGGAA
ATGAAAGCACGGATTGTTAAATTTCCTACCTATGCAGAGAAGGAACGTATTCAACGTAAGCTGGACCTGATTAACGAGGT
TTTAGTCAAGTACTTTGACCGTCTGCCTGAGGATGAGTTGCTCTTTTTGGACCTGTCAGAAAATATCCTGGATAGGATGC
ACGATAAACGTATCCCCAATATCGAGGAAATCTATGATGATGCTTTCGAGCAGGTGCTCAAGAAGAAAACCTTTACTTTT
AATGACTACCTTTATTTGGGCTATTTTTTACAAAAGTGTCGCAATGAAGCTAGTTATGATCGAAAGATCTTCAAACAGAT
TGAGCAAAAATTACTCCAACAAGAACTGAGTTCAGACGAGTTTTATAATATTGAATTTTTGGTAGCAGTTATGGATGTGG
CTGCTGTCTATGCTTTTCATGATGATTATAAGGATATCATGCCATTGTTGAAGAAAATACATTGGATTATTGAGCAAGCC
CAACTCCACACCTATAAGGCAGGGGTTCTAGAATTAGAAGCTAAATACTATGTTAAAATCGCTAAGGATAAGGATAGGGC
CAAGAAACTTTATCAACAAGCTCTAAAGTTAGGGGAAATCTTGGAGGATCCTGCTATTATTGCAGATATTAAGATGGAAA
TGAAAAACGATGGGATTGAGTAA

Domains

Predicted by InterproScan.

• ComR tetratricopeptide (ComR_TPR) (75-294)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR/comR2	Streptococcus sobrinus strain NIDR 6715-7	90.333	100	0.903
comR/comR1	Streptococcus sobrinus strain NIDR 6715-7	79	100	0.79
comR	Streptococcus salivarius strain HSISS4	42.809	99.667	0.427
comR	Streptococcus thermophilus LMG 18311	42.475	99.667	0.423
comR	Streptococcus thermophilus LMD-9	42.14	99.667	0.42
comR	Streptococcus salivarius SK126	42.14	99.667	0.42