Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   DG474_RS00205 Genome accession   NZ_CP029257
Coordinates   35259..36608 (+) Length   449 a.a.
NCBI ID   WP_255778244.1    Uniprot ID   -
Organism   Streptococcus oralis strain CCUG 53468     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 30259..41608
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DG474_RS00170 (DG474_00165) plsX 30418..31410 (+) 993 WP_255778241.1 phosphate acyltransferase PlsX -
  DG474_RS00175 (DG474_00170) - 31416..31652 (+) 237 WP_000136435.1 acyl carrier protein -
  DG474_RS00180 (DG474_00175) - 32088..32276 (+) 189 WP_049501355.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  DG474_RS00185 (DG474_00180) - 32294..32461 (+) 168 WP_255778242.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  DG474_RS00190 (DG474_00185) - 32471..32659 (+) 189 WP_000722238.1 hypothetical protein -
  DG474_RS00200 (DG474_00195) comA 33093..35246 (+) 2154 WP_255778243.1 peptide cleavage/export ABC transporter ComA Regulator
  DG474_RS00205 (DG474_00200) comB 35259..36608 (+) 1350 WP_255778244.1 competence pheromone export protein ComB Regulator
  DG474_RS00210 (DG474_00205) purC 36777..37484 (+) 708 WP_000043287.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
  DG474_RS00215 (DG474_00210) - 37541..41266 (+) 3726 WP_255778245.1 phosphoribosylformylglycinamidine synthase -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 49869.80 Da        Isoelectric Point: 5.2339

>NTDB_id=291386 DG474_RS00205 WP_255778244.1 35259..36608(+) (comB) [Streptococcus oralis strain CCUG 53468]
MKPEFLESAEFYHRRYHNFSSRVILPMSLLLVFLLGFAVFAEKEISLSTRATVEPSRIIANIQSTSNQRIVTNYLEENKL
VKQGDLLVQYQQGAEAVQVEAYASQLEMLKDQKKQLGYLQSSLKEGSDQFPEADKFGYQEMFRDYLSQANGLRSNVSQQN
ASISSQNAVASQSQAEIGNLISQTEDKIRDYKTAKSAIETGAQLDSQNAAYSFYQTYKNQAGDDSQVKSQVIAQVDAQIA
QLESSLATYRVQYAGSGAQQAYATGLDSQLESLKSQHLVKVGQELTLLDQKILEAESGKKVQGGLLDKGKITASEDGVLH
LNPETSESTMVAEGTLLAQLYPSLEKEGKTKLTAYLSSKDVARVKIGDSVRYTTTNDAKNQIFLDSTITSIDATATKTEQ
GNFFKIEAETNLTSEQAATLRYGLEGRLQMITGKKSYFRYFWDQFLNKG

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=291386 DG474_RS00205 WP_255778244.1 35259..36608(+) (comB) [Streptococcus oralis strain CCUG 53468]
ATGAAACCAGAATTTTTAGAAAGTGCGGAGTTTTACCATCGTCGTTACCATAATTTTTCCAGTCGGGTGATTTTACCTAT
GTCGCTTCTGCTCGTGTTTCTGCTAGGATTTGCAGTCTTTGCAGAGAAGGAAATTAGTTTGTCTACCAGAGCCACTGTCG
AACCTAGTCGGATTATTGCCAATATCCAGTCGACTAGCAATCAACGGATTGTGACCAATTATCTGGAAGAGAACAAGTTG
GTCAAGCAAGGAGATCTGCTCGTTCAGTACCAGCAAGGGGCGGAGGCTGTCCAGGTAGAGGCATATGCCAGTCAATTGGA
GATGCTAAAGGATCAAAAAAAGCAGTTGGGGTATTTGCAATCCAGTTTGAAAGAGGGGAGCGATCAATTTCCAGAGGCGG
ATAAGTTTGGTTATCAGGAGATGTTTAGAGACTATCTCAGCCAAGCGAATGGTCTAAGAAGTAATGTTTCTCAACAAAAT
GCCAGCATCTCTTCTCAAAATGCGGTAGCAAGTCAGAGCCAGGCCGAGATTGGCAATCTTATCAGCCAAACAGAGGATAA
AATCCGAGACTACAAAACAGCTAAGTCGGCGATTGAAACAGGAGCTCAACTGGATAGTCAAAATGCAGCCTACTCATTTT
ATCAGACCTATAAAAACCAAGCTGGAGATGATTCGCAAGTTAAATCACAAGTTATTGCACAGGTGGATGCACAAATTGCC
CAGCTAGAGTCTAGTTTAGCTACCTATCGTGTGCAGTATGCGGGTTCTGGAGCTCAACAAGCCTATGCAACGGGACTGGA
TAGTCAACTGGAATCGCTCAAATCTCAGCACTTAGTCAAAGTCGGTCAGGAATTAACTCTTTTGGATCAGAAAATTTTAG
AAGCAGAATCGGGTAAGAAGGTACAGGGAGGTCTCCTAGATAAAGGGAAGATTACAGCAAGTGAGGATGGGGTGCTACAC
CTCAATCCTGAGACTAGTGAATCTACGATGGTCGCAGAAGGAACCCTGCTAGCCCAACTCTACCCATCCTTGGAAAAAGA
AGGGAAAACCAAACTCACAGCTTATCTCAGTTCAAAAGATGTTGCTAGAGTCAAGATTGGGGACTCTGTTCGTTATACTA
CGACTAATGATGCGAAGAATCAAATTTTCCTGGATTCCACGATTACAAGTATTGATGCGACAGCTACAAAAACTGAACAA
GGAAATTTCTTTAAAATTGAGGCGGAGACTAATTTAACTTCGGAGCAGGCTGCAACACTTCGTTATGGTTTAGAAGGCCG
CCTGCAGATGATCACAGGGAAGAAAAGCTATTTCCGTTATTTTTGGGATCAATTTCTAAATAAAGGGTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus mitis SK321

82.589

99.777

0.824
  comB Streptococcus pneumoniae Rx1

81.696

99.777

0.815
  comB Streptococcus pneumoniae D39

81.696

99.777

0.815
  comB Streptococcus pneumoniae R6

81.696

99.777

0.815
  comB Streptococcus pneumoniae TIGR4

81.473

99.777

0.813
  comB Streptococcus mitis NCTC 12261

81.473

99.777

0.813
  comB Streptococcus gordonii str. Challis substr. CH1

54.867

100

0.552

Multiple sequence alignment