Detailed information NTG0291157

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: DEH83_RS01490
• Genome accession: NZ_CP029207
• Coordinates: 311025..313175 (-)
• Length: 716 a.a.
• NCBI ID: WP_255776894.1
• Uniprot ID: -
• Organism: Streptococcus constellatus strain TCV107
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 306025..318175

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DEH83_RS01465 (DEH83_01445)	-	306425..307138 (+)	714	WP_020997680.1	CPBP family intramembrane glutamic endopeptidase	-
DEH83_RS01470 (DEH83_01450)	comE/blpR	307307..308053 (+)	747	WP_255776891.1	response regulator transcription factor	Regulator
DEH83_RS01475 (DEH83_01455)	-	308454..309365 (+)	912	WP_255776892.1	sensor histidine kinase	-
DEH83_RS01480 (DEH83_01460)	-	309410..309559 (-)	150	WP_003025431.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
DEH83_RS01485 (DEH83_01465)	-	309653..311014 (-)	1362	WP_255776893.1	bacteriocin secretion accessory protein	-
DEH83_RS01490 (DEH83_01470)	comA/nlmT	311025..313175 (-)	2151	WP_255776894.1	peptide cleavage/export ABC transporter	Regulator
DEH83_RS01495 (DEH83_01480)	-	313658..314032 (+)	375	WP_255776895.1	hypothetical protein	-
DEH83_RS01500 (DEH83_01485)	-	314088..314693 (-)	606	WP_255776896.1	superoxide dismutase	-
DEH83_RS01505 (DEH83_01490)	holA	314763..315800 (-)	1038	WP_255776897.1	DNA polymerase III subunit delta	-
DEH83_RS01510 (DEH83_01495)	cvfB	315881..316735 (-)	855	WP_187328290.1	RNA-binding virulence regulatory protein CvfB	-
DEH83_RS01515 (DEH83_01500)	frr	316848..317405 (-)	558	WP_003069936.1	ribosome recycling factor	-
DEH83_RS01520 (DEH83_01505)	pyrH	317409..318149 (-)	741	WP_003069937.1	UMP kinase	-

Sequence

Protein

• Length: 716 a.a.
• Molecular weight: 80405.85 Da
• Isoelectric Point: 9.1744

>NTDB_id=291157 DEH83_RS01490 WP_255776894.1 311025..313175(-) (comA/nlmT) [Streptococcus constellatus strain TCV107]
MNVKKTFVPQIDARDCGVAALASIAKYYGSDYSLAHLRELAKTSKEGTTALGIVQAAQEIGFETRPIQGDMSLFDMEAIP
YPFIVHVQKKAKLPHYYVIYKNTKKGLLVGDPDPSVKITKISKETFATEWTGVAIFLAPEPSYKPHKDKKNGLTSFLPLI
FKQSSLIFYIVLASLLVTLINIVSSYYLQGILDEYIPNQMKSTLGIVSIGLIITYILQQMMSFSRDYLLIILSQRLTIDV
ILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDLFILIMVGGVLLLQNTNLFFLTLLAIPIYTVI
IFAFIKPFEKMNHDVMQSNSMVNSAIIEDINGIETIKSLTSEESRYQKIDSEFVDYLNKTFKLSKYSIMQTALKQGAQFI
LNVVILWVGASLAMSQKISIGQLITFNALLSYFTSPLESIINLQTKLQSAKVANNRLNEVYLVESEFKTKQVITEKNFLA
GDVTFHNVSYKYGFGRDTLSDINLTIKIGDKVSLVGISGSGKTTLAKMMVHFYEPYKGQIRLNGNDLKMIDKKTLRQYIN
YLPQQAYIFSGSILENLTLGTNQIFSQEEIIRACEIAEIRSDIEQMPMGYQTELSDGAGLSGGQKQRIALARALLTKSPI
LILDEATSGLDVLTEKKVIDNLMGLKDKTIIFVAHRLSISKRTNQVIVLDKGQIIETGSHAELMERQGFYHHLFNK

Nucleotide

• Length: 2151 bp

>NTDB_id=291157 DEH83_RS01490 WP_255776894.1 311025..313175(-) (comA/nlmT) [Streptococcus constellatus strain TCV107]
GTGAATGTTAAGAAAACATTTGTTCCTCAAATAGATGCAAGAGATTGCGGTGTCGCTGCGCTTGCTTCCATTGCAAAATA
CTATGGTTCAGACTACTCTCTTGCACATCTGAGAGAACTTGCTAAGACAAGTAAAGAAGGGACAACGGCTCTTGGAATTG
TTCAAGCAGCACAAGAAATAGGTTTTGAGACACGACCGATTCAAGGGGATATGTCCTTGTTTGATATGGAAGCTATTCCC
TATCCTTTTATCGTTCATGTTCAGAAAAAAGCTAAACTCCCACATTATTATGTTATCTATAAAAATACGAAAAAAGGTCT
GCTAGTTGGAGATCCTGACCCAAGTGTAAAAATAACTAAGATATCAAAAGAGACATTTGCAACAGAATGGACTGGTGTTG
CTATTTTTTTAGCACCAGAACCTAGCTATAAACCACATAAGGATAAGAAGAATGGGCTTACTAGCTTTTTACCACTCATC
TTTAAACAGAGCTCTTTGATTTTTTATATTGTCTTAGCTAGTTTGCTTGTGACCCTCATCAACATTGTTAGTTCTTATTA
TCTGCAAGGGATTTTGGATGAATACATTCCAAATCAGATGAAATCAACTCTTGGAATCGTTTCAATTGGGCTTATCATTA
CTTACATCTTGCAGCAAATGATGAGTTTTTCCAGAGATTACTTATTGATTATACTTAGTCAGCGACTAACCATCGATGTA
ATTTTATCATATATTCGACACATTTTTGAATTACCGATGTCTTTTTTTGCTACGAGACGCACTGGAGAGATTATTTCTCG
TTTTACAGATGCTAATTCCATTATTGATGCTCTCGCTTCTACAATACTTTCACTCTTTCTTGACCTTTTTATTTTGATAA
TGGTAGGAGGGGTACTATTATTACAGAATACTAACCTTTTCTTCCTCACTCTGCTTGCTATTCCTATCTATACAGTGATT
ATTTTTGCTTTTATAAAGCCTTTTGAAAAAATGAATCATGACGTCATGCAAAGTAATTCCATGGTAAATTCTGCTATTAT
CGAAGATATTAATGGCATTGAAACGATTAAATCTTTAACCAGCGAAGAAAGTCGTTACCAAAAGATTGATAGTGAGTTTG
TCGATTATCTGAATAAGACTTTCAAGCTAAGTAAATATTCCATTATGCAGACAGCTCTCAAACAAGGAGCACAATTTATT
TTGAATGTTGTTATTCTATGGGTTGGAGCCTCTCTGGCTATGTCTCAAAAAATTTCGATTGGACAGCTGATTACTTTTAA
TGCACTCCTTTCGTATTTTACAAGTCCACTTGAAAGTATCATCAATCTGCAAACCAAGCTGCAATCGGCTAAGGTTGCCA
ACAATCGGTTGAATGAAGTCTATCTGGTAGAATCCGAATTCAAAACCAAACAAGTCATTACAGAGAAAAATTTCTTGGCT
GGTGATGTTACGTTCCATAATGTTTCCTATAAATACGGTTTCGGACGAGATACGTTATCGGATATTAACTTAACAATAAA
AATAGGAGATAAGGTGAGCTTAGTCGGTATCAGTGGTTCGGGAAAGACAACGCTTGCCAAAATGATGGTTCATTTTTATG
AGCCTTATAAAGGGCAAATCCGTCTCAATGGAAATGATCTTAAAATGATTGATAAGAAGACGCTTCGTCAATATATCAAT
TATTTACCACAACAAGCCTATATTTTTAGTGGTTCTATCTTAGAAAACCTTACATTAGGGACGAATCAAATATTTTCTCA
AGAAGAGATTATTCGCGCTTGTGAAATTGCAGAAATTCGTTCGGATATTGAACAAATGCCTATGGGATATCAAACAGAAT
TGTCCGATGGAGCTGGTCTATCAGGTGGACAAAAGCAAAGAATTGCTCTAGCACGCGCCCTCTTAACAAAGTCACCAATT
CTTATTCTTGATGAGGCAACGAGCGGATTGGATGTTCTAACTGAGAAAAAGGTCATTGACAATCTGATGGGCTTAAAAGA
CAAAACGATTATTTTTGTTGCTCATCGTCTCAGCATTTCAAAGCGGACAAATCAAGTGATTGTTCTTGATAAAGGGCAGA
TTATTGAAACTGGATCCCACGCTGAATTGATGGAAAGACAAGGCTTTTATCATCATTTATTTAATAAATAA

Domains

Predicted by InterproScan.

• Peptidase C39 family (Peptidase_C39) (6-141)

• ABC transporter transmembrane region (ABC_membrane) (167-437)

• ABC transporter (ABC_tran) (499-648)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	72.073	99.022	0.714
comA	Streptococcus mitis NCTC 12261	66.339	99.581	0.661
comA	Streptococcus mitis SK321	66.199	99.581	0.659
comA	Streptococcus pneumoniae D39	65.638	99.581	0.654
comA	Streptococcus pneumoniae Rx1	65.638	99.581	0.654
comA	Streptococcus pneumoniae R6	65.638	99.581	0.654
comA	Streptococcus gordonii str. Challis substr. CH1	65.498	99.581	0.652
comA	Streptococcus pneumoniae TIGR4	65.217	99.581	0.649