Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   SK637_RS00310 Genome accession   NZ_CP028415
Coordinates   59534..60883 (+) Length   449 a.a.
NCBI ID   WP_033687907.1    Uniprot ID   -
Organism   Streptococcus mitis strain SK637     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 54534..65883
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SK637_RS00265 (SK637_00054) - 55264..55392 (+) 129 WP_000658145.1 smi_0059.1 family bacteriocin-like peptide -
  SK637_RS09810 (SK637_00055) - 55404..55559 (+) 156 WP_001004585.1 hypothetical protein -
  SK637_RS00275 (SK637_00056) - 55594..55785 (+) 192 WP_033687902.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  SK637_RS00285 (SK637_00057) - 56022..56189 (+) 168 WP_001047582.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  SK637_RS09980 - 56193..56408 (+) 216 WP_078934268.1 bacteriocin immunity protein -
  SK637_RS00295 (SK637_00059) - 56488..56667 (+) 180 WP_033687904.1 hypothetical protein -
  SK637_RS00305 (SK637_00060) comA 57368..59521 (+) 2154 WP_033687906.1 peptide cleavage/export ABC transporter ComA Regulator
  SK637_RS00310 (SK637_00061) comB 59534..60883 (+) 1350 WP_033687907.1 competence pheromone export protein ComB Regulator
  SK637_RS00315 (SK637_00062) purC 61054..61761 (+) 708 WP_033687908.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
  SK637_RS10265 - 61763..61906 (+) 144 WP_080710150.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
  SK637_RS00325 (SK637_00063) - 61963..65688 (+) 3726 WP_033687909.1 phosphoribosylformylglycinamidine synthase -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 49643.54 Da        Isoelectric Point: 5.3970

>NTDB_id=284672 SK637_RS00310 WP_033687907.1 59534..60883(+) (comB) [Streptococcus mitis strain SK637]
MKPEFLESAEFYNRRYHNFSSRVIVPMSLLLVCLLGFATVAEKEMSLSTRATVEPSRILANIQSTSNNRILVNHLEENKL
VKKGELLVQYQEGAEGVQAEAYASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAIETGASLASQNLAYSLYQSYKSQGEENPQAKAQAVAQVEAQLS
QLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQYLAKVGQELTLLDQKILEAESGKKVQGSLLDKGKITASEDGVLH
LNPETSDSTMVAEGTLLAQLYPSLEKEGKAKLTAYLSSKDVSRVKVGDSVRYTTTHDAKNQIVLDSTITSIDATATKTEK
GNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLHYYLDQFLNKE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=284672 SK637_RS00310 WP_033687907.1 59534..60883(+) (comB) [Streptococcus mitis strain SK637]
ATGAAACCAGAATTTTTAGAAAGTGCGGAGTTTTATAATCGTCGTTACCATAATTTTTCCAGTCGAGTGATTGTACCCAT
GTCCCTTCTACTTGTCTGTTTACTTGGCTTTGCAACTGTTGCAGAGAAGGAGATGAGTTTGTCTACTAGAGCTACTGTCG
AGCCTAGTCGTATCCTTGCAAATATCCAGTCAACTAGCAACAATCGTATTCTTGTCAATCATTTGGAAGAAAATAAGCTG
GTTAAAAAGGGGGAGCTTCTGGTTCAATACCAGGAAGGGGCAGAGGGTGTCCAAGCGGAGGCCTATGCTAGTCAGTTGGA
CATGCTTAAGGATCAAAAAAAGCAATTGGAGTATTTGCAAAAAAGTCTGCAAGAAGGGGAGAATCACTTTCCAGAGGAGG
ATAAGTTTGGCTACCAAGCCACCTTTCGCGACTACATCAGTCAAGCAGGCAGTCTTAGGGCTAGTACATCGCAACAAAAT
GAGACCATCGCGTCCCAGAATGCAGCAGCTAGTCAAACCCAAGCCGAAATCGGCAACCTCATCAGCCAAACAGAGGCTAA
AATTCGCGATTACCAGACAGCTAAGTCAGCTATTGAAACAGGCGCTTCCTTGGCCAGTCAGAATCTAGCCTATTCTCTCT
ACCAGTCCTACAAGTCTCAGGGTGAGGAAAATCCGCAAGCTAAAGCTCAGGCAGTTGCGCAGGTTGAAGCACAGCTTTCT
CAGTTAGAATCCAGTCTCGCTACTTACCGTGTCCAGTATGCGGGTTCAGGTACCCAGCAAGCCTATGCGTCAGGCTTAAG
CAGTCAATTGGAGTCTCTCAAATCCCAATACTTGGCAAAGGTTGGTCAAGAATTGACCCTTCTAGACCAGAAAATCTTGG
AGGCAGAGTCAGGCAAGAAGGTTCAGGGAAGTCTTCTAGACAAGGGGAAAATTACGGCTAGTGAGGATGGGGTGCTTCAC
CTTAATCCTGAGACTAGTGATTCTACCATGGTAGCAGAAGGTACCCTACTAGCCCAACTCTATCCATCCTTGGAAAAAGA
AGGGAAAGCCAAACTTACAGCTTATCTAAGTTCAAAAGATGTATCAAGAGTCAAGGTCGGTGATTCTGTTCGCTATACGA
CGACTCATGATGCTAAGAATCAAATTGTCTTAGATTCCACTATTACAAGTATTGATGCGACAGCTACCAAGACTGAAAAA
GGTAATTTCTTTAAAATTGAGGCGGAGACTAATCTAACTTCGGAGCAGGCTGAAAAACTTCGGTACGGGGTGGAAGGTCG
CCTGCAGATGATTACGGGAAAGAAAAGTTATCTACATTATTATTTGGATCAATTTTTGAACAAAGAGTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus mitis SK321

96.659

100

0.967
  comB Streptococcus pneumoniae Rx1

95.1

100

0.951
  comB Streptococcus pneumoniae D39

95.1

100

0.951
  comB Streptococcus pneumoniae R6

95.1

100

0.951
  comB Streptococcus pneumoniae TIGR4

94.878

100

0.949
  comB Streptococcus mitis NCTC 12261

94.878

100

0.949
  comB Streptococcus gordonii str. Challis substr. CH1

56.222

100

0.563

Multiple sequence alignment