Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   C7K38_RS03385 Genome accession   NZ_CP027783
Coordinates   699637..700905 (+) Length   422 a.a.
NCBI ID   WP_123934663.1    Uniprot ID   A0AA37XN61
Organism   Tetragenococcus osmophilus strain JCM 31126     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 694637..705905
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C7K38_RS03370 (C7K38_03355) uvrC 695992..697800 (+) 1809 WP_123934657.1 excinuclease ABC subunit UvrC -
  C7K38_RS03375 (C7K38_03360) msrA 697877..698713 (-) 837 WP_123934659.1 peptide-methionine (S)-S-oxide reductase MsrA -
  C7K38_RS03380 (C7K38_03365) rlmH 698825..699304 (-) 480 WP_123934661.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  C7K38_RS03385 (C7K38_03370) htrA 699637..700905 (+) 1269 WP_123934663.1 S1C family serine protease Regulator
  C7K38_RS03390 (C7K38_03375) ytpR 700945..701556 (-) 612 WP_028791029.1 YtpR family tRNA-binding protein -
  C7K38_RS03395 (C7K38_03380) - 701596..702057 (-) 462 WP_123934665.1 universal stress protein -
  C7K38_RS03400 (C7K38_03385) - 702073..702393 (-) 321 WP_028791027.1 thioredoxin family protein -
  C7K38_RS03405 (C7K38_03390) pepA 702482..703558 (-) 1077 WP_123936663.1 glutamyl aminopeptidase -
  C7K38_RS03410 (C7K38_03395) - 703924..704268 (+) 345 WP_123934667.1 hypothetical protein -
  C7K38_RS03415 (C7K38_03400) pepV 704357..705772 (-) 1416 WP_123934669.1 dipeptidase PepV -

Sequence

Protein


Download         Length: 422 a.a.        Molecular weight: 44267.12 Da        Isoelectric Point: 3.7512

>NTDB_id=280602 C7K38_RS03385 WP_123934663.1 699637..700905(+) (htrA) [Tetragenococcus osmophilus strain JCM 31126]
MAKKDESSNSKKNGWLKKFGISLLGGILGGLLVIGGFYYFADDIGNPFQTDEATSTSGVTDDDENVQVSDVKVDVDSDTT
SAVDKVQDAVVSIVNLQNTSSQESGGLFDTEQQEDDGEEQPAGEGSGVIYKKDDDTAYIVTNNHVVAGQSGLEVLMADGS
RESAELVGTDTYTDLAVLKISSDNVDTVATFGDSDDLQVGEPAIAIGSPLGSDYANSVTQGIISSLNRLVSSEDDSGEAV
STNAIQTDAAINPGNSGGPLINASGQVIGINSSKIASSGQAGVSVEGMGFAIPSSDVTDIINELEQNGEITRPALGISML
DLSAIPTEQREQLLQLPDSVENGVVVQNPGSNSPASEAGMEQYDVITKVDDQEIKDTTELRAALYKRSVGDNLKLSFYRD
GEAQSANIKLSEDQSIIERNNN

Nucleotide


Download         Length: 1269 bp        

>NTDB_id=280602 C7K38_RS03385 WP_123934663.1 699637..700905(+) (htrA) [Tetragenococcus osmophilus strain JCM 31126]
ATGGCAAAAAAAGATGAGTCCTCAAACTCTAAAAAGAATGGATGGCTTAAAAAGTTTGGAATTAGCCTGTTAGGAGGAAT
CCTCGGTGGTTTGCTTGTTATTGGCGGATTTTATTATTTTGCTGACGATATAGGCAATCCATTTCAAACAGATGAAGCTA
CTTCCACGTCTGGTGTAACCGATGATGACGAAAATGTCCAAGTAAGTGATGTCAAAGTAGATGTCGATAGTGACACAACT
TCTGCAGTAGATAAAGTTCAAGATGCTGTTGTCTCTATTGTAAATCTACAAAATACATCCTCACAAGAAAGCGGTGGTCT
TTTCGATACGGAACAACAAGAAGATGACGGAGAAGAACAACCTGCCGGTGAGGGTAGTGGTGTCATTTATAAAAAAGACG
ATGATACAGCTTATATTGTAACAAATAATCACGTAGTTGCTGGGCAAAGTGGCCTAGAAGTTTTAATGGCAGATGGTTCA
AGAGAAAGTGCTGAGCTCGTTGGAACAGACACTTACACTGACTTAGCCGTTTTAAAAATTTCTTCTGATAATGTAGACAC
GGTTGCTACATTTGGCGATTCTGATGATTTACAAGTAGGAGAACCGGCGATTGCTATTGGCTCACCTTTAGGTTCTGATT
ATGCTAATTCTGTAACACAAGGTATTATTTCTTCTTTAAATCGTTTAGTATCAAGTGAAGATGACTCTGGTGAAGCCGTT
AGTACTAATGCTATTCAAACAGACGCCGCAATTAACCCAGGTAATTCTGGTGGTCCATTAATCAATGCTAGTGGGCAAGT
TATTGGAATAAATTCTAGTAAAATTGCTAGTTCTGGACAAGCAGGCGTAAGTGTTGAAGGTATGGGCTTTGCTATACCAA
GTAGCGATGTTACTGACATTATTAACGAACTAGAACAAAATGGCGAAATTACTCGTCCAGCGTTAGGTATTTCTATGCTT
GATTTAAGTGCGATACCTACAGAACAAAGAGAACAACTCCTACAGCTTCCTGATTCTGTAGAAAATGGCGTTGTCGTACA
AAATCCTGGGAGTAATTCTCCAGCAAGTGAAGCAGGAATGGAACAATATGATGTCATTACCAAAGTTGACGATCAAGAGA
TCAAAGATACCACGGAACTTCGAGCTGCTTTGTACAAAAGATCTGTCGGGGATAATTTGAAATTAAGCTTCTATCGTGAT
GGAGAAGCACAATCTGCAAATATAAAATTATCCGAAGATCAATCCATTATTGAACGAAACAATAACTAA

Domains

Predicted by InterproScan.

Trypsin-like peptidase domain (Trypsin_2)

(125-270)

PDZ domain (PDZ_2)

(313-410)

Peptidase family M50 (Peptidase_M50)

(286-414)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

51.613

95.498

0.493
  htrA Streptococcus mitis NCTC 12261

51.842

90.047

0.467
  htrA Streptococcus gordonii str. Challis substr. CH1

49.745

92.891

0.462
  htrA Streptococcus pneumoniae Rx1

51.047

90.521

0.462
  htrA Streptococcus pneumoniae D39

51.047

90.521

0.462
  htrA Streptococcus pneumoniae R6

51.047

90.521

0.462
  htrA Streptococcus pneumoniae TIGR4

51.047

90.521

0.462

Multiple sequence alignment