Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   C7K40_RS07160 Genome accession   NZ_CP027771
Coordinates   1421362..1422072 (-) Length   236 a.a.
NCBI ID   WP_002985645.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain DMG1800716     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1416362..1427072
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C7K40_RS07145 (C7K40_07140) rnc 1418068..1418760 (-) 693 WP_011284596.1 ribonuclease III -
  C7K40_RS07150 (C7K40_07145) vicX 1419204..1420013 (-) 810 WP_002985641.1 MBL fold metallo-hydrolase Regulator
  C7K40_RS07155 (C7K40_07150) vicK 1420017..1421369 (-) 1353 WP_002995609.1 cell wall metabolism sensor histidine kinase VicK Regulator
  C7K40_RS07160 (C7K40_07155) vicR 1421362..1422072 (-) 711 WP_002985645.1 response regulator YycF Regulator
  C7K40_RS07165 (C7K40_07160) - 1422234..1423268 (-) 1035 WP_172456391.1 DUF3114 domain-containing protein -
  C7K40_RS07170 (C7K40_07165) - 1423324..1424571 (-) 1248 WP_063629692.1 AMP-binding protein -
  C7K40_RS07175 (C7K40_07170) - 1424528..1425676 (-) 1149 WP_063629691.1 acetyl-CoA C-acyltransferase -
  C7K40_RS07180 (C7K40_07175) - 1425645..1426214 (-) 570 WP_063629690.1 hypothetical protein -
  C7K40_RS07185 (C7K40_07180) - 1426349..1427062 (-) 714 WP_301182272.1 MIP/aquaporin family protein -

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 27083.99 Da        Isoelectric Point: 4.9038

>NTDB_id=280461 C7K40_RS07160 WP_002985645.1 1421362..1422072(-) (vicR) [Streptococcus pyogenes strain DMG1800716]
MKKILIVDDEKPISDIIKFNLTKEGYDIVTAFDGREAVTIFEEEKPDLIILDLMLPELDGLEVAKEIRKTSHVPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTETIETAVAEENASSGTQELTIGNLQILPDAFVAKKHGQEVE
LTHREFELLHHLANHMGQVMTREHLLEIVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYYMKSYD

Nucleotide


Download         Length: 711 bp        

>NTDB_id=280461 C7K40_RS07160 WP_002985645.1 1421362..1422072(-) (vicR) [Streptococcus pyogenes strain DMG1800716]
ATGAAAAAAATACTTATTGTGGATGATGAAAAACCGATTTCTGACATTATTAAGTTTAATTTGACAAAAGAAGGTTATGA
CATTGTTACAGCTTTTGATGGACGCGAAGCGGTAACAATTTTTGAAGAAGAAAAGCCAGATTTAATTATTCTTGATTTGA
TGCTCCCTGAGTTGGACGGTCTTGAAGTAGCCAAGGAAATTCGTAAAACCAGTCATGTCCCGATTATTATGTTGTCGGCT
AAAGATAGTGAGTTTGACAAGGTTATTGGACTTGAAATTGGGGCTGATGATTACGTGACCAAGCCCTTTTCTAATCGGGA
ACTGCTGGCGCGTGTCAAGGCTCATCTGCGTCGTACCGAAACTATTGAAACGGCTGTTGCAGAAGAAAATGCTTCTTCAG
GTACACAGGAACTAACCATTGGTAATTTACAGATTTTACCAGATGCGTTTGTTGCTAAAAAACATGGTCAAGAGGTAGAG
TTGACCCATCGTGAATTTGAACTATTGCATCATCTAGCTAACCATATGGGTCAGGTGATGACACGAGAACACTTATTGGA
AATTGTTTGGGGATATGATTATTTCGGCGATGTGCGCACGGTTGATGTGACTGTTCGTCGTCTCCGTGAAAAAATTGAAG
ACACACCAAGTCGTCCTGAGTATATTTTAACAAGACGTGGTGTTGGGTACTACATGAAATCTTATGACTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-113)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-231)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

90.254

100

0.903
  micA Streptococcus pneumoniae Cp1015

79.06

99.153

0.784
  covR Streptococcus salivarius strain HSISS4

44.828

98.305

0.441
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.397

98.305

0.436
  scnR Streptococcus mutans UA159

36.91

98.729

0.364

Multiple sequence alignment