Detailed information NTG0280448

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: C7K40_RS04705
• Genome accession: NZ_CP027771
• Coordinates: 910454..911290 (+)
• Length: 278 a.a.
• NCBI ID: WP_023079425.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain DMG1800716
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 905454..916290

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C7K40_RS04675 (C7K40_04675)	-	905942..906376 (+)	435	WP_023079442.1	hypothetical protein	-
C7K40_RS04680 (C7K40_04680)	-	906426..907337 (-)	912	WP_023079407.1	diacylglycerol kinase family protein	-
C7K40_RS04685 (C7K40_04685)	-	907454..908104 (-)	651	WP_002984629.1	hemolysin III family protein	-
C7K40_RS04690 (C7K40_04690)	-	908101..908541 (-)	441	WP_002989774.1	DUF1836 domain-containing protein	-
C7K40_RS04695 (C7K40_04695)	ylqF	908760..909608 (+)	849	WP_023612970.1	ribosome biogenesis GTPase YlqF	-
C7K40_RS04700 (C7K40_04700)	-	909598..910389 (+)	792	WP_063629505.1	ribonuclease HII	-
C7K40_RS04705 (C7K40_04705)	dprA	910454..911290 (+)	837	WP_023079425.1	DNA-processing protein DprA	Machinery gene
C7K40_RS04710 (C7K40_04710)	topA	911398..913527 (+)	2130	WP_011017773.1	type I DNA topoisomerase	-
C7K40_RS09480	-	913602..914459 (-)	858	Protein_856	LysR family transcriptional regulator	-
C7K40_RS04725 (C7K40_04725)	-	914499..915044 (+)	546	Protein_857	PTS sugar transporter subunit IIC	-
C7K40_RS04730 (C7K40_04730)	-	915059..916051 (+)	993	WP_047235809.1	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 31046.98 Da
• Isoelectric Point: 8.5827

>NTDB_id=280448 C7K40_RS04705 WP_023079425.1 910454..911290(+) (dprA) [Streptococcus pyogenes strain DMG1800716]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEDR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=280448 C7K40_RS04705 WP_023079425.1 910454..911290(+) (dprA) [Streptococcus pyogenes strain DMG1800716]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCTGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATGGAATTCAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACTGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACTATC
GCTATTATTGGAACAGGATTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGACCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.266	100	0.673
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis SK321	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.072	100	0.601
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367