Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   D9C18_RS10495 Genome accession   NZ_CP032865
Coordinates   1962477..1963679 (+) Length   400 a.a.
NCBI ID   WP_014481472.1    Uniprot ID   -
Organism   Bacillus subtilis subsp. subtilis strain N3-1     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1957477..1968679
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D9C18_RS10475 (D9C18_10475) walK 1957558..1959393 (+) 1836 WP_009968432.1 cell wall metabolism sensor histidine kinase WalK -
  D9C18_RS10480 (D9C18_10480) walH 1959383..1960750 (+) 1368 WP_014481474.1 WalRK two-component regulatory system regulator WalH -
  D9C18_RS10485 (D9C18_10485) walI 1960737..1961579 (+) 843 WP_014481473.1 WalRK two-component regulatory system regulator WalI -
  D9C18_RS10490 (D9C18_10490) vicX 1961601..1962395 (+) 795 WP_003226939.1 MBL fold metallo-hydrolase Regulator
  D9C18_RS10495 (D9C18_10495) htrA 1962477..1963679 (+) 1203 WP_014481472.1 serine protease HtrC Regulator
  D9C18_RS10500 (D9C18_10500) - 1963700..1963832 (+) 133 Protein_2002 hypothetical protein -
  D9C18_RS10505 (D9C18_10505) - 1963860..1964012 (+) 153 Protein_2003 ATP-binding protein -
  D9C18_RS10510 (D9C18_10510) rocR 1963994..1965379 (-) 1386 WP_003244510.1 arginine utilization regulatory protein RocR -
  D9C18_RS10515 (D9C18_10515) - 1965606..1965890 (+) 285 WP_015715052.1 autorepressor SdpR family transcription factor -
  D9C18_RS10520 (D9C18_10520) - 1965890..1966525 (+) 636 WP_014481470.1 SdpI family protein -
  D9C18_RS10525 (D9C18_10525) - 1966853..1967263 (+) 411 WP_231560755.1 SdpA family antimicrobial peptide system protein -
  D9C18_RS10530 (D9C18_10530) - 1967248..1968201 (+) 954 WP_014481469.1 sporulation-delaying protein SdpB family protein -

Sequence

Protein


Download         Length: 400 a.a.        Molecular weight: 42761.51 Da        Isoelectric Point: 5.1904

>NTDB_id=279937 D9C18_RS10495 WP_014481472.1 1962477..1963679(+) (htrA) [Bacillus subtilis subsp. subtilis strain N3-1]
MVDYEREEEHTTPEQPKRSKKGYFLSSLIGVIVGAVLMAFIMPYLSNEGLDTGALDQQQNNNGRESIRTVNVSVNNAVTK
IVSNVSPAVVGVVNIQKSDIWGESGEAGSGSGVIYKKNDNSAYVVTNHHVIEGASQIEISLKDGSRVSADLVGSDQLMDL
AVLRVKSDKIKAVADFGNSDKVKSGEPVIAIGNPLGLEFAGSVTQGVISGTERAIPVDSNGDGQPDWNAEVLQTDAAINP
GNSGGALLNMDGKVIGINSMKIAESAVEGIGLSIPSKLVIPVIEDLERYGKVKRPFLGIEMKSLSDIASYHWDETLKLPK
NVTNGVVVMGVDAFSPAGKAGLKELDVITEFDGYKVNDIVDLRKRLYQKKVGDRVKVKFYRGGKEKSVDIKLSSADQLGS

Nucleotide


Download         Length: 1203 bp        

>NTDB_id=279937 D9C18_RS10495 WP_014481472.1 1962477..1963679(+) (htrA) [Bacillus subtilis subsp. subtilis strain N3-1]
ATGGTGGATTACGAACGTGAGGAAGAACATACTACTCCTGAACAGCCAAAGAGAAGCAAAAAAGGATATTTTCTTTCGAG
TCTGATTGGCGTGATTGTCGGTGCCGTATTAATGGCGTTTATCATGCCGTACCTTTCAAATGAAGGGCTGGATACAGGCG
CCTTAGATCAGCAGCAAAACAACAATGGCCGGGAATCAATCAGGACGGTGAATGTCAGTGTCAACAATGCCGTCACCAAG
ATTGTCAGCAATGTGTCGCCCGCCGTTGTCGGTGTTGTGAACATCCAAAAATCAGATATTTGGGGAGAGAGCGGCGAGGC
TGGGAGCGGCTCTGGCGTCATCTATAAGAAAAATGACAACTCCGCTTATGTCGTGACCAACCATCATGTCATCGAAGGCG
CTTCCCAAATTGAAATCAGCTTGAAAGACGGTTCACGTGTATCAGCTGATCTTGTCGGCAGCGACCAGCTGATGGACCTT
GCCGTTTTACGGGTGAAAAGCGATAAAATTAAAGCAGTCGCCGATTTCGGAAATTCAGATAAAGTGAAGTCTGGCGAGCC
GGTTATTGCGATCGGGAACCCGTTAGGCCTTGAGTTTGCAGGCTCTGTCACACAAGGCGTCATCTCAGGTACGGAGAGGG
CGATCCCAGTGGATTCAAACGGTGATGGACAGCCTGACTGGAATGCAGAAGTCCTGCAAACAGATGCGGCCATTAACCCT
GGGAACAGCGGCGGCGCTTTGTTAAATATGGATGGGAAGGTCATTGGCATCAATTCAATGAAAATTGCCGAGTCGGCGGT
TGAAGGGATTGGCCTGTCGATTCCATCTAAGCTCGTGATCCCTGTGATAGAGGATTTAGAGAGATACGGAAAGGTCAAAC
GCCCGTTCCTTGGCATTGAGATGAAATCCCTAAGCGACATCGCAAGCTATCATTGGGATGAAACATTAAAGCTTCCTAAG
AACGTCACCAATGGAGTGGTTGTGATGGGTGTAGACGCCTTTTCACCTGCCGGAAAAGCAGGGCTGAAGGAACTGGATGT
CATCACGGAATTTGACGGATACAAAGTAAATGATATTGTTGACCTGCGAAAACGGCTTTATCAGAAAAAAGTCGGTGACC
GGGTGAAGGTGAAGTTTTACCGCGGCGGAAAAGAAAAATCTGTAGACATCAAGCTGTCCTCCGCAGACCAATTAGGCAGT
TAA

Domains

Predicted by InterProScan.

PDZ domain (PDZ_2)

(295-392)

Trypsin-like peptidase domain (Trypsin_2)

(110-257)

Peptidase family M50 (Peptidase_M50)

(231-395)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

43.829

99.25

0.435
  htrA Streptococcus gordonii str. Challis substr. CH1

41.791

100

0.42
  htrA Streptococcus mitis NCTC 12261

43.264

96.5

0.417
  htrA Streptococcus pneumoniae TIGR4

45.455

82.5

0.375
  htrA Streptococcus pneumoniae D39

45.455

82.5

0.375
  htrA Streptococcus pneumoniae Rx1

45.455

82.5

0.375
  htrA Streptococcus pneumoniae R6

45.455

82.5

0.375