Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   SPYM_RS09245 Genome accession   NC_009332
Coordinates   1839182..1840405 (+) Length   407 a.a.
NCBI ID   WP_002981947.1    Uniprot ID   -
Organism   Streptococcus pyogenes str. Manfredo     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1834182..1845405
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPYM_RS09230 (SpyM51835) - 1836977..1838075 (-) 1099 Protein_1792 IS30 family transposase -
  SPYM_RS09240 (SpyM51836) rlmH 1838491..1838970 (-) 480 WP_011889262.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  SPYM_RS09245 (SpyM51837) htrA 1839182..1840405 (+) 1224 WP_002981947.1 S1C family serine protease Regulator
  SPYM_RS09250 (SpyM51838) spo0J 1840494..1841270 (+) 777 WP_002981939.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 407 a.a.        Molecular weight: 42758.40 Da        Isoelectric Point: 7.3920

>NTDB_id=27882 SPYM_RS09245 WP_002981947.1 1839182..1840405(+) (htrA) [Streptococcus pyogenes str. Manfredo]
MPSMKHILKSLSVLLIGFLGGLIAIITFNNLYPHSPSKINSGKATTSNMVFNNTTNTTKAVKAVQNAVVSVINYQDNPSS
SLSNPYTKLFGEGRSKENKDAELSIFSEGSGVIYRKDGNSAYVVTNNHVIDGAKRIEILMADGSKVVGELVGADTYSDLA
VVKISSDKIKTVAEFADSTKLNVGEVAIAIGSPLGTQYANSVTQGIVSSLSRTVTLKNENGETVSTNAIQTDAAINPGNS
GGPLINIEGQVIGINSSKISSTPTGSNGNSGAVEGIGFAIPSTDVIKIIKQLETNGEVIRPALGISMVNLNDLSTNALSQ
INIPTSVTGGIVVAEVKEGMPASGKLAQYDVITEIDGKIVNSISDLQSSLYGHDINDTIKVTFYRGTTKKKADIKLTKTT
QDLTKTQ

Nucleotide


Download         Length: 1224 bp        

>NTDB_id=27882 SPYM_RS09245 WP_002981947.1 1839182..1840405(+) (htrA) [Streptococcus pyogenes str. Manfredo]
ATGCCAAGTATGAAACATATCTTAAAATCCTTAAGTGTTTTACTAATTGGATTTTTAGGAGGATTAATAGCAATTATTAC
ATTTAATAATCTCTACCCACATTCTCCTTCAAAAATAAATTCAGGTAAGGCAACAACTAGTAATATGGTTTTTAACAACA
CAACCAATACTACTAAAGCTGTCAAAGCTGTTCAAAATGCAGTTGTATCAGTTATTAATTATCAAGATAACCCTTCTTCA
TCCCTTTCTAACCCTTATACAAAACTCTTTGGAGAAGGGCGTTCAAAAGAGAATAAGGATGCTGAATTATCTATTTTTAG
TGAAGGATCTGGGGTCATTTATCGAAAAGATGGCAACTCCGCTTACGTTGTTACTAATAACCATGTTATCGACGGAGCTA
AACGGATTGAAATTCTTATGGCAGACGGATCTAAAGTTGTTGGTGAATTAGTTGGAGCTGATACTTATTCGGATTTAGCT
GTTGTTAAGATCTCTTCAGATAAGATAAAAACAGTAGCTGAATTTGCAGATTCTACAAAACTAAATGTTGGAGAAGTTGC
TATTGCTATCGGCAGCCCACTAGGAACACAATACGCTAATTCTGTTACTCAAGGAATCGTCTCTAGTTTAAGTCGTACTG
TAACTTTAAAAAACGAGAATGGTGAGACTGTCTCAACAAATGCTATTCAGACAGATGCTGCTATCAACCCTGGAAACTCT
GGTGGACCACTAATTAATATTGAGGGGCAAGTAATCGGAATTAATTCAAGTAAAATTTCTTCTACCCCAACTGGTAGCAA
CGGTAATAGTGGTGCTGTTGAAGGAATTGGTTTTGCTATCCCATCTACTGATGTTATTAAAATTATTAAACAACTAGAAA
CTAATGGTGAAGTTATCAGACCTGCTCTTGGAATATCCATGGTCAATTTAAATGACTTATCCACAAATGCTCTTAGCCAA
ATTAATATTCCAACTAGTGTAACTGGTGGTATTGTAGTAGCAGAAGTTAAGGAAGGAATGCCGGCATCTGGCAAACTTGC
TCAGTACGATGTGATTACAGAAATTGATGGCAAAATAGTTAATTCAATTAGTGATTTACAAAGTAGTCTATACGGACACG
ATATTAATGATACTATTAAAGTAACTTTTTATAGAGGAACTACAAAGAAAAAAGCAGATATCAAATTAACAAAAACTACT
CAAGATTTGACTAAAACGCAGTAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(301-396)

Trypsin-like peptidase domain (Trypsin_2)

(109-254)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

61.634

99.263

0.612
  htrA Streptococcus gordonii str. Challis substr. CH1

55.473

98.771

0.548
  htrA Streptococcus mitis NCTC 12261

53.317

100

0.533
  htrA Streptococcus pneumoniae Rx1

53.071

100

0.531
  htrA Streptococcus pneumoniae D39

53.071

100

0.531
  htrA Streptococcus pneumoniae R6

53.071

100

0.531
  htrA Streptococcus pneumoniae TIGR4

53.071

100

0.531

Multiple sequence alignment