Detailed information NTG0027883

Bioinformatically predicted

Overview

• Name: radC
• Type: Machinery gene
• Locus tag: ECDH10B_RS19445
• Genome accession: NC_010473
• Coordinates: 3907491..3908159 (-)
• Length: 222 a.a.
• NCBI ID: WP_001350561.1
• Uniprot ID: B1X972
• Organism: Escherichia coli str. K-12 substr. DH10B
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 3902491..3913159

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ECDH10B_RS19415 (ECDH10B_3814)	rfaQ	3902664..3903734 (-)	1071	WP_001350560.1	lipopolysaccharide core heptosyltransferase RfaQ	-
ECDH10B_RS19420 (ECDH10B_3815)	waaA	3904140..3905417 (+)	1278	WP_000891564.1	lipid IV(A) 3-deoxy-D-manno-octulosonic acid transferase	-
ECDH10B_RS19425 (ECDH10B_3816)	coaD	3905425..3905904 (+)	480	WP_001171866.1	pantetheine-phosphate adenylyltransferase	-
ECDH10B_RS19430 (ECDH10B_3817)	mutM	3905943..3906752 (-)	810	WP_001114543.1	bifunctional DNA-formamidopyrimidine glycosylase/DNA-(apurinic or apyrimidinic site) lyase	-
ECDH10B_RS19435 (ECDH10B_3818)	rpmG	3906850..3907017 (-)	168	WP_001051798.1	50S ribosomal protein L33	-
ECDH10B_RS19440 (ECDH10B_3819)	rpmB	3907038..3907274 (-)	237	WP_000091955.1	50S ribosomal protein L28	-
ECDH10B_RS19445 (ECDH10B_3820)	radC	3907491..3908159 (-)	669	WP_001350561.1	DNA repair protein RadC	Machinery gene
ECDH10B_RS19450 (ECDH10B_3821)	coaBC	3908331..3909551 (+)	1221	WP_000050139.1	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC	-
ECDH10B_RS19455 (ECDH10B_3822)	dut	3909529..3909987 (+)	459	WP_000976073.1	dUTP diphosphatase	-
ECDH10B_RS19460 (ECDH10B_3823)	slmA	3910094..3910690 (+)	597	WP_000818601.1	nucleoid occlusion factor SlmA	-
ECDH10B_RS19465 (ECDH10B_3824)	pyrE	3910727..3911368 (-)	642	WP_000806177.1	orotate phosphoribosyltransferase	-
ECDH10B_RS19470	rph	3911434..3912150 (-)	717	WP_001247096.1	ribonuclease PH	-
ECDH10B_RS19475 (ECDH10B_3826)	yicC	3912277..3913140 (+)	864	WP_000621340.1	YicC/YloC family endoribonuclease	-

Sequence

Protein

• Length: 222 a.a.
• Molecular weight: 25343.46 Da
• Isoelectric Point: 8.4958

>NTDB_id=27883 ECDH10B_RS19445 WP_001350561.1 3907491..3908159(-) (radC) [Escherichia coli str. K-12 substr. DH10B]
MKNNSQLLMPREKMLKFGISALTDVELLALFLRTGTRGKDVLTLAKEMLENFGSLYGLLTSEYEQFSGVHGIGVAKFAQL
KGIAELARRYYNVRMREESPLLSPEMTREFLQSQLTGEEREIFMVIFLDSQHRVITHRRLFSGTLNHVEVHPREIIREAI
KINASALILAHNHPSGCAEPSKADKLITERIIKSCQFMDLRVLDHIVIGRGEYVSFAERGWI

Nucleotide

• Length: 669 bp

>NTDB_id=27883 ECDH10B_RS19445 WP_001350561.1 3907491..3908159(-) (radC) [Escherichia coli str. K-12 substr. DH10B]
GTGAAAAACAATTCACAGCTGTTGATGCCGCGCGAAAAAATGCTGAAGTTTGGTATTAGCGCCTTAACGGATGTCGAGCT
GCTGGCGCTATTTCTGCGTACCGGAACGCGCGGTAAAGATGTATTAACCCTGGCAAAAGAGATGCTGGAGAATTTCGGCT
CTCTTTATGGCTTGTTAACCTCTGAATATGAACAATTTAGTGGCGTTCATGGAATTGGCGTGGCGAAATTTGCCCAGTTA
AAGGGGATTGCTGAACTGGCGCGGCGTTACTACAACGTGCGGATGCGTGAAGAAAGCCCTTTACTCAGCCCGGAGATGAC
GAGGGAATTTTTACAAAGCCAGCTCACGGGTGAGGAGCGGGAGATCTTTATGGTGATCTTTCTCGACTCCCAACACCGGG
TTATAACGCATAGGCGTCTTTTTTCCGGCACGCTAAACCATGTTGAAGTCCATCCTCGGGAAATTATCCGCGAAGCGATA
AAAATAAACGCCTCGGCGCTGATCCTTGCACATAATCACCCTTCGGGTTGTGCTGAACCCAGTAAAGCGGATAAACTCAT
TACTGAACGGATAATAAAGAGTTGTCAGTTCATGGATTTACGCGTGCTCGACCATATCGTGATTGGGCGTGGAGAGTATG
TTTCTTTTGCCGAACGCGGCTGGATTTAA

Domains

Predicted by InterProScan.

• UPF0758 N-terminal (UPF0758_N) (9-77)

• RadC-like JAB domain (RadC) (103-220)

3D structure

• AlphaFold DB: B1X972

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
radC	Haemophilus influenzae Rd KW20	49.55	100	0.496