Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   SPYM_RS07190 Genome accession   NC_009332
Coordinates   1412514..1413224 (-) Length   236 a.a.
NCBI ID   WP_002985645.1    Uniprot ID   -
Organism   Streptococcus pyogenes str. Manfredo     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1407514..1418224
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPYM_RS07175 (SpyM51426) rnc 1409221..1409913 (-) 693 WP_002985639.1 ribonuclease III -
  SPYM_RS07180 (SpyM51427) vicX 1410356..1411165 (-) 810 WP_002985641.1 MBL fold metallo-hydrolase Regulator
  SPYM_RS07185 (SpyM51428) vicK 1411169..1412521 (-) 1353 WP_002990673.1 cell wall metabolism sensor histidine kinase VicK Regulator
  SPYM_RS07190 (SpyM51429) vicR 1412514..1413224 (-) 711 WP_002985645.1 response regulator YycF Regulator
  SPYM_RS07195 (SpyM51430) - 1413386..1414420 (-) 1035 WP_011184290.1 DUF3114 domain-containing protein -
  SPYM_RS07200 (SpyM51431) - 1414476..1415723 (-) 1248 WP_011284594.1 AMP-binding protein -
  SPYM_RS07205 (SpyM51432) - 1415680..1416828 (-) 1149 WP_011889082.1 acetyl-CoA C-acyltransferase -
  SPYM_RS07210 (SpyM51433) - 1416797..1417366 (-) 570 WP_011889083.1 hypothetical protein -
  SPYM_RS07215 (SpyM51434) - 1417501..1418214 (-) 714 WP_307777291.1 MIP/aquaporin family protein -

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 27083.99 Da        Isoelectric Point: 4.9038

>NTDB_id=27871 SPYM_RS07190 WP_002985645.1 1412514..1413224(-) (vicR) [Streptococcus pyogenes str. Manfredo]
MKKILIVDDEKPISDIIKFNLTKEGYDIVTAFDGREAVTIFEEEKPDLIILDLMLPELDGLEVAKEIRKTSHVPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTETIETAVAEENASSGTQELTIGNLQILPDAFVAKKHGQEVE
LTHREFELLHHLANHMGQVMTREHLLEIVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYYMKSYD

Nucleotide


Download         Length: 711 bp        

>NTDB_id=27871 SPYM_RS07190 WP_002985645.1 1412514..1413224(-) (vicR) [Streptococcus pyogenes str. Manfredo]
ATGAAAAAAATACTTATTGTGGATGATGAAAAACCGATTTCTGACATTATTAAGTTTAATTTGACAAAAGAAGGTTATGA
CATTGTTACAGCTTTTGATGGACGCGAAGCGGTAACAATTTTTGAAGAAGAAAAGCCAGATTTAATTATTCTTGATTTGA
TGCTCCCTGAGTTGGACGGTCTTGAAGTAGCCAAGGAAATTCGTAAAACCAGTCATGTCCCGATTATTATGTTGTCGGCT
AAAGATAGTGAGTTTGACAAGGTTATTGGACTTGAAATTGGGGCTGATGATTACGTGACCAAGCCCTTTTCTAATCGGGA
ATTGCTGGCGCGTGTCAAGGCTCATCTGCGTCGTACCGAAACTATTGAAACGGCTGTTGCAGAAGAAAATGCTTCTTCAG
GTACACAGGAACTAACCATTGGCAATTTACAGATTTTACCAGATGCGTTTGTTGCTAAAAAACATGGTCAAGAGGTAGAG
TTGACTCATCGTGAATTTGAACTATTGCATCATCTAGCTAACCATATGGGTCAGGTGATGACACGAGAACACTTATTGGA
AATTGTTTGGGGATATGATTATTTTGGCGATGTGCGCACGGTTGATGTGACTGTTCGTCGTCTCCGTGAAAAAATTGAAG
ACACACCAAGTCGTCCTGAGTATATTTTAACAAGACGTGGTGTTGGGTACTACATGAAATCTTATGACTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-113)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-231)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

90.254

100

0.903
  micA Streptococcus pneumoniae Cp1015

79.06

99.153

0.784
  covR Streptococcus salivarius strain HSISS4

44.828

98.305

0.441
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.397

98.305

0.436
  scnR Streptococcus mutans UA159

36.91

98.729

0.364

Multiple sequence alignment