Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/comE1   Type   Machinery gene
Locus tag   C7A17_RS21605 Genome accession   NZ_CP027657
Coordinates   4674622..4674945 (+) Length   107 a.a.
NCBI ID   WP_106740346.1    Uniprot ID   A0A2R3QTX5
Organism   Ectopseudomonas mendocina strain NEB698     
Function   dsDNA binding (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 4655043..4674532 4674622..4674945 flank 90


Gene organization within MGE regions


Location: 4655043..4674945
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C7A17_RS21510 (C7A17_21510) - 4655043..4656212 (+) 1170 WP_106740300.1 nucleotide sugar dehydrogenase -
  C7A17_RS21515 (C7A17_21515) - 4656209..4657504 (+) 1296 WP_106740303.1 flippase -
  C7A17_RS21520 (C7A17_21520) - 4657501..4658289 (+) 789 WP_158704694.1 FkbM family methyltransferase -
  C7A17_RS21525 (C7A17_21525) - 4658286..4659125 (+) 840 WP_106740307.1 glycosyltransferase -
  C7A17_RS21530 (C7A17_21530) - 4659243..4659896 (+) 654 WP_106740310.1 CatB-related O-acetyltransferase -
  C7A17_RS21535 (C7A17_21535) - 4659961..4660764 (+) 804 WP_158704695.1 bifunctional 2-polyprenyl-6-hydroxyphenol methylase/3-demethylubiquinol 3-O-methyltransferase UbiG -
  C7A17_RS21540 (C7A17_21540) - 4660754..4662001 (+) 1248 WP_158704696.1 glycosyltransferase family A protein -
  C7A17_RS21545 (C7A17_21545) - 4662105..4663034 (+) 930 WP_234035827.1 UDP-glucuronic acid decarboxylase family protein -
  C7A17_RS21550 (C7A17_21550) - 4663060..4664034 (+) 975 WP_106740320.1 glycosyltransferase -
  C7A17_RS21555 (C7A17_21555) - 4664024..4664836 (+) 813 WP_199796353.1 class I SAM-dependent methyltransferase -
  C7A17_RS21560 (C7A17_21560) - 4664833..4665933 (+) 1101 WP_106740325.1 glycosyltransferase family 1 protein -
  C7A17_RS21565 (C7A17_21565) gmd 4666043..4667161 (+) 1119 WP_106740327.1 GDP-mannose 4,6-dehydratase -
  C7A17_RS21570 (C7A17_21570) - 4667164..4668132 (+) 969 WP_106740330.1 GDP-L-fucose synthase -
  C7A17_RS21575 (C7A17_21575) - 4668125..4668877 (+) 753 WP_106740333.1 glycosyltransferase -
  C7A17_RS21580 (C7A17_21580) - 4668907..4669803 (+) 897 WP_106740335.1 glycosyltransferase -
  C7A17_RS21585 (C7A17_21585) - 4669796..4670938 (+) 1143 WP_234035828.1 glycosyltransferase family 4 protein -
  C7A17_RS21590 (C7A17_21590) - 4670941..4671876 (+) 936 WP_106740340.1 SDR family oxidoreductase -
  C7A17_RS21595 (C7A17_21595) - 4671899..4672450 (+) 552 WP_106740343.1 sugar transferase -
  C7A17_RS21600 (C7A17_21600) - 4672547..4674532 (+) 1986 WP_106743095.1 nucleoside-diphosphate sugar epimerase/dehydratase -
  C7A17_RS21605 (C7A17_21605) comEA/comE1 4674622..4674945 (+) 324 WP_106740346.1 helix-hairpin-helix domain-containing protein Machinery gene

Sequence

Protein


Download         Length: 107 a.a.        Molecular weight: 11295.99 Da        Isoelectric Point: 5.8395

>NTDB_id=278692 C7A17_RS21605 WP_106740346.1 4674622..4674945(+) (comEA/comE1) [Ectopseudomonas mendocina strain NEB698]
MLKVRLSSLLFAVLAFFSLAATAAETPKTESAKPAAVQVAQVAVVNLNTADAATLQRELLGIGATKAQAIVAYREEHGNF
ASVDELLEVKGIGEATLEKNRDKLSVN

Nucleotide


Download         Length: 324 bp        

>NTDB_id=278692 C7A17_RS21605 WP_106740346.1 4674622..4674945(+) (comEA/comE1) [Ectopseudomonas mendocina strain NEB698]
ATGCTGAAAGTCCGTCTTTCCTCTCTGCTGTTCGCTGTTCTTGCTTTCTTCTCTCTGGCTGCAACCGCAGCTGAAACTCC
GAAAACCGAAAGTGCCAAACCGGCTGCTGTTCAGGTGGCGCAGGTTGCTGTGGTCAATCTGAATACCGCTGATGCTGCAA
CCTTGCAGCGCGAGCTTTTGGGTATTGGAGCGACAAAGGCGCAAGCGATTGTGGCTTACCGGGAAGAGCACGGTAACTTT
GCCTCGGTCGATGAGTTGCTTGAGGTCAAGGGTATCGGTGAGGCGACGCTAGAGAAAAATCGCGATAAGTTGAGTGTTAA
CTGA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(44-104)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2R3QTX5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/comE1 Glaesserella parasuis strain SC1401

50

99.065

0.495
  comEA Legionella pneumophila str. Paris

44.762

98.131

0.439
  comEA Legionella pneumophila strain ERS1305867

44.762

98.131

0.439
  comEA Vibrio cholerae C6706

45

93.458

0.421
  comEA Vibrio cholerae strain A1552

45

93.458

0.421
  comEA Vibrio parahaemolyticus RIMD 2210633

43.299

90.654

0.393
  comEA Vibrio campbellii strain DS40M4

42.268

90.654

0.383

Multiple sequence alignment