Detailed information NTG0277956

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: SPV_RS09870
• Genome accession: NZ_CP027540
• Coordinates: 1840169..1840630 (-)
• Length: 153 a.a.
• NCBI ID: WP_000250534.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain D39V
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1835169..1845630

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPV_RS09840 (SPV_1850)	-	1835473..1836297 (-)	825	WP_000727904.1	membrane protein insertase YidC	-
SPV_RS09845 (SPV_1851)	rnpA	1836272..1836643 (-)	372	WP_000739246.1	ribonuclease P protein component	-
SPV_RS11980 (SPV_1852)	-	1836660..1836791 (-)	132	WP_000768904.1	hypothetical protein	-
SPV_RS09850 (SPV_1853)	-	1836792..1837982 (-)	1191	WP_000167757.1	acetate kinase	-
SPV_RS09855 (SPV_1854)	comYH	1838033..1838986 (-)	954	WP_000345135.1	class I SAM-dependent methyltransferase	Machinery gene
SPV_RS09860 (SPV_2427)	-	1839047..1839641 (-)	595	Protein_1837	class I SAM-dependent methyltransferase	-
SPV_RS09865 (SPV_1857)	comGG/cglG	1839778..1840191 (-)	414	WP_000265622.1	competence type IV pilus minor pilin ComGG	Machinery gene
SPV_RS09870 (SPV_1858)	comGF/cglF	1840169..1840630 (-)	462	WP_000250534.1	competence type IV pilus minor pilin ComGF	Machinery gene
SPV_RS09875 (SPV_1859)	comGE/cglE	1840593..1840895 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
SPV_RS09880 (SPV_1860)	comGD/cglD	1840858..1841262 (-)	405	WP_000588026.1	competence type IV pilus minor pilin ComGD	Machinery gene
SPV_RS09885 (SPV_1861)	comGC/cglC	1841255..1841581 (-)	327	WP_000738626.1	comG operon protein ComGC	Machinery gene
SPV_RS09890 (SPV_1862)	comGB/cglB	1841583..1842599 (-)	1017	WP_074196785.1	competence type IV pilus assembly protein ComGB	Machinery gene
SPV_RS09895 (SPV_1863)	comGA/cglA/cilD	1842547..1843488 (-)	942	WP_000249564.1	competence type IV pilus ATPase ComGA	Machinery gene
SPV_RS09900 (SPV_1864)	-	1843564..1843929 (-)	366	WP_000286412.1	DUF1033 family protein	-
SPV_RS09905 (SPV_1865)	-	1844080..1845138 (-)	1059	WP_000649468.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17972.67 Da
• Isoelectric Point: 9.6092

>NTDB_id=277956 SPV_RS09870 WP_000250534.1 1840169..1840630(-) (comGF/cglF) [Streptococcus pneumoniae strain D39V]
MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQAMSQLLISEVRYQQQSEQKEWLLFVDQLEVELDRSQFEKVEGN
RLYMKQDGKDIAIGKSKSDDFRKTNARGRGYQPMVYGLKSVRITEDNQLVRFHFQFQKGLEREFIYRVEKEKS

Nucleotide

• Length: 462 bp

>NTDB_id=277956 SPV_RS09870 WP_000250534.1 1840169..1840630(-) (comGF/cglF) [Streptococcus pneumoniae strain D39V]
ATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAAGGTCAAGGCTTTTACCTTGTTAGAATCCCTGCTTGCCCTCAT
TGTCATCAGTGGGGGATTACTCCTTTTTCAAGCTATGAGTCAGCTCCTCATTTCAGAAGTTCGCTACCAGCAACAAAGCG
AGCAAAAGGAGTGGCTCTTGTTTGTGGACCAACTTGAGGTAGAATTAGACCGTTCGCAGTTCGAAAAAGTAGAAGGCAAT
CGCCTATACATGAAGCAAGATGGCAAGGACATCGCCATCGGTAAGTCAAAGTCAGATGATTTCCGTAAAACGAATGCTCG
TGGTCGAGGTTATCAGCCTATGGTTTATGGACTCAAATCTGTACGGATTACAGAGGACAATCAACTGGTTCGCTTTCATT
TCCAGTTCCAAAAAGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAGAAAAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (45-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	100	100	1
comGF/cglF	Streptococcus pneumoniae D39	100	100	1
comGF/cglF	Streptococcus pneumoniae R6	100	100	1
comGF/cglF	Streptococcus pneumoniae TIGR4	100	100	1
comGF/cglF	Streptococcus mitis SK321	90.85	100	0.909
comGF/cglF	Streptococcus mitis NCTC 12261	89.542	100	0.895