Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   CFK76_RS08835 Genome accession   NZ_CP032652
Coordinates   1747437..1748696 (-) Length   419 a.a.
NCBI ID   WP_025016471.1    Uniprot ID   -
Organism   Latilactobacillus sakei strain LZ217     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1742437..1753696
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CFK76_RS08815 (CFK76_08815) - 1743019..1744362 (-) 1344 WP_151388575.1 NCS2 family permease -
  CFK76_RS08820 (CFK76_08820) add 1744532..1745557 (+) 1026 WP_035147601.1 adenosine deaminase -
  CFK76_RS08825 (CFK76_08825) - 1745614..1746273 (-) 660 WP_025016470.1 hypothetical protein -
  CFK76_RS08830 (CFK76_08830) rlmH 1746413..1746892 (-) 480 WP_011373797.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  CFK76_RS08835 (CFK76_08835) htrA 1747437..1748696 (-) 1260 WP_025016471.1 S1C family serine protease Regulator
  CFK76_RS08840 (CFK76_08840) vicX 1748830..1749636 (-) 807 WP_016264363.1 MBL fold metallo-hydrolase Regulator
  CFK76_RS08845 (CFK76_08845) - 1749671..1750492 (-) 822 WP_035147596.1 two-component system regulatory protein YycI -
  CFK76_RS08850 (CFK76_08850) - 1750497..1751828 (-) 1332 WP_035147594.1 YycH family regulatory protein -

Sequence

Protein


Download         Length: 419 a.a.        Molecular weight: 42698.80 Da        Isoelectric Point: 9.4566

>NTDB_id=277226 CFK76_RS08835 WP_025016471.1 1747437..1748696(-) (htrA) [Latilactobacillus sakei strain LZ217]
MNQNSGLMKTAVVAVISALIGGGAAYAGFSRLGSSANDVTTATQTPTKAGATKISNIKVNSSSQTTTAFQKVNTSVVSVV
NLQKQQQSTGDLSSLFGSGSTNSNSSSSKSSSSDLEESSEGSGLIYEKKDGKAYIVTNNHVVAGSDKIEVILSDGTKLEA
SLVGTDAVSDLAVLKINGTKVKKTATFGDSDSIKAGESVLAIGSPLGSEYATSVTQGIISAKKRTIDVTDETTGQTTGQA
TVIQTDTAINPGNSGGPLVNMAGQVVGINSMKLASNGDTTVEGMGFAIPSNEVVKIINQLVANGKVVRPALGISVIDLTN
ISSTQQSSVLKLPSTVNSGVVVASVTSNSVAKKAGISKYDVIVGLGGKTVSSVADLHTILYSYAMNSTTEIQYYHNGSLK
KANVKLTQAASSDSTTTTK

Nucleotide


Download         Length: 1260 bp        

>NTDB_id=277226 CFK76_RS08835 WP_025016471.1 1747437..1748696(-) (htrA) [Latilactobacillus sakei strain LZ217]
ATGAATCAAAATTCAGGATTAATGAAAACAGCGGTTGTTGCAGTTATTTCAGCATTGATTGGTGGGGGCGCAGCCTATGC
CGGTTTTTCTCGACTCGGCAGTTCGGCCAATGATGTCACGACTGCAACGCAGACGCCTACTAAAGCGGGGGCAACTAAGA
TTAGTAATATCAAAGTGAACTCATCATCACAGACGACAACAGCCTTCCAAAAGGTTAATACATCAGTTGTATCCGTTGTG
AACTTACAAAAACAACAACAATCAACCGGTGACCTGAGTTCATTATTTGGTTCAGGCAGCACCAACAGCAATAGTAGTTC
TTCTAAGAGCAGTAGCAGTGATTTAGAAGAATCCAGTGAAGGTTCAGGTTTAATCTACGAGAAAAAAGACGGCAAAGCTT
ACATCGTGACGAATAATCACGTGGTTGCTGGTTCTGATAAAATCGAAGTCATTTTGAGTGATGGCACAAAATTGGAAGCT
AGTTTAGTTGGGACAGATGCTGTTTCTGATTTGGCTGTCTTAAAAATTAACGGGACTAAAGTGAAGAAGACGGCAACGTT
TGGTGATTCAGATAGTATCAAAGCTGGTGAATCAGTTCTTGCGATCGGCTCACCATTGGGTTCAGAATACGCAACTTCTG
TCACACAAGGGATCATTTCTGCTAAGAAACGGACAATTGATGTGACGGACGAAACAACTGGCCAAACAACTGGTCAAGCG
ACTGTTATTCAAACTGATACAGCGATTAACCCTGGGAACTCAGGTGGCCCATTAGTTAATATGGCCGGTCAAGTTGTTGG
GATTAATTCAATGAAGTTAGCCTCAAATGGTGATACGACAGTTGAAGGGATGGGCTTTGCTATTCCAAGTAACGAAGTTG
TTAAAATTATTAATCAATTAGTGGCTAACGGGAAAGTCGTTAGACCAGCACTTGGGATTAGTGTGATAGATTTAACCAAT
ATTTCATCAACACAACAATCTTCAGTATTAAAACTACCATCAACCGTCAATAGCGGGGTAGTGGTTGCCTCAGTAACAAG
CAATTCAGTTGCTAAGAAAGCTGGGATTAGTAAATACGATGTGATTGTCGGTTTAGGCGGCAAGACGGTTTCAAGCGTTG
CAGACTTACACACAATCCTATACAGTTACGCGATGAATAGTACAACTGAAATTCAGTACTACCATAATGGCAGCTTGAAA
AAAGCGAATGTTAAACTTACACAAGCAGCTTCATCAGATAGTACGACAACAACTAAATAA

Domains

Predicted by InterProScan.

Peptidase family M50 (Peptidase_M50)

(284-413)

PDZ domain (PDZ_2)

(309-406)

Trypsin-like peptidase domain (Trypsin_2)

(121-268)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mitis NCTC 12261

45.209

97.136

0.439
  htrA Streptococcus gordonii str. Challis substr. CH1

42.512

98.807

0.42
  htrA Streptococcus mutans UA159

45.968

88.783

0.408
  htrA Streptococcus pneumoniae TIGR4

48.424

83.294

0.403
  htrA Streptococcus pneumoniae R6

48.424

83.294

0.403
  htrA Streptococcus pneumoniae Rx1

48.424

83.294

0.403
  htrA Streptococcus pneumoniae D39

48.424

83.294

0.403