Detailed information NTG0262376

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: C0J00_RS10410
• Genome accession: NZ_CP025536
• Coordinates: 2063462..2064610 (+)
• Length: 382 a.a.
• NCBI ID: WP_104968785.1
• Uniprot ID: A0A2L0D730
• Organism: Streptococcus pluranimalium strain TH11417
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2058462..2069610

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C0J00_RS10390 (C0J00_10395)	-	2059666..2062260 (+)	2595	WP_104968783.1	YfhO family protein	-
C0J00_RS10405 (C0J00_10410)	rlmH	2062682..2063161 (-)	480	WP_104968784.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
C0J00_RS10410 (C0J00_10415)	htrA	2063462..2064610 (+)	1149	WP_104968785.1	S1C family serine protease	Regulator
C0J00_RS10415 (C0J00_10420)	spo0J	2064664..2065431 (+)	768	WP_104968786.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 382 a.a.
• Molecular weight: 40559.09 Da
• Isoelectric Point: 4.3484

>NTDB_id=262376 C0J00_RS10410 WP_104968785.1 2063462..2064610(+) (htrA) [Streptococcus pluranimalium strain TH11417]
MAGAYLMLYFSNNLSTPLNNSQAKAKTSNVVYNNTTNTTKAAKKVQDAVVSVINYQKNTDSSLNDLYSQMFGGDNDKRSE
DDLSVYSEGSGVIYRKEGGSAYIVTNNHVIDGAENIEIMLADGTKVVGELVGSDTYSDLAVVKISDEKVSTVAEFADSDK
LNVGEVAIAMGSPLGSEYANSVTQGIVSSLSRTVTLKNEEGETISTNAIQTDAAINPGNSGGALINIEGQVIGINSSKIS
STSTAREAVEGMGFAIPSNDVIKIINQLEKNGQVTRPALGISMANLSDLSTSAISELNIPNKLTGGIVVATVQDKMPASG
KLKQYDVITEIDGEEITSTSDLQSILYGHEIGDTIKITYYRGKDKQTTDIKLSKSTQDLENN

Nucleotide

• Length: 1149 bp

>NTDB_id=262376 C0J00_RS10410 WP_104968785.1 2063462..2064610(+) (htrA) [Streptococcus pluranimalium strain TH11417]
ATGGCAGGAGCTTATCTCATGCTCTATTTTTCCAATAACCTGTCAACTCCTTTGAATAATTCGCAAGCCAAAGCCAAAAC
AAGCAATGTGGTTTACAATAATACTACCAACACGACTAAAGCAGCCAAAAAAGTCCAAGATGCTGTTGTATCAGTTATTA
ACTACCAAAAGAATACCGATTCTTCTTTAAATGATCTTTATAGTCAAATGTTTGGTGGAGACAATGATAAGCGTTCTGAA
GATGATTTGAGTGTCTACAGCGAAGGCTCTGGCGTTATTTATCGAAAAGAAGGTGGATCAGCTTACATCGTCACTAACAA
TCACGTTATTGATGGAGCTGAAAATATTGAAATTATGCTTGCTGATGGAACAAAAGTCGTCGGAGAACTTGTTGGATCTG
ATACTTACTCCGATTTAGCTGTTGTCAAAATTTCTGATGAAAAAGTATCTACAGTTGCGGAGTTCGCAGACTCTGATAAA
TTAAACGTTGGAGAAGTAGCGATTGCAATGGGTAGCCCTCTAGGAAGTGAATATGCTAACTCTGTTACACAAGGAATTGT
GTCAAGTCTAAGCCGCACAGTAACGCTTAAAAATGAGGAGGGTGAAACCATTTCAACCAATGCTATCCAAACAGATGCTG
CCATCAACCCTGGCAACTCTGGTGGTGCTTTGATTAATATTGAAGGACAAGTTATTGGTATCAATTCAAGTAAAATCTCA
TCTACCTCAACTGCTCGCGAAGCCGTAGAAGGCATGGGATTTGCTATCCCATCTAATGATGTCATCAAAATTATCAATCA
GTTAGAAAAAAATGGACAAGTAACTCGCCCAGCACTAGGCATCTCTATGGCGAATCTTAGCGATCTCTCAACAAGTGCTA
TCTCAGAGCTTAATATTCCAAATAAGCTCACTGGAGGTATTGTTGTTGCCACTGTTCAAGATAAAATGCCTGCCTCAGGT
AAACTGAAACAATATGACGTCATCACTGAAATTGATGGTGAAGAAATAACATCAACCAGTGATTTACAAAGTATTCTTTA
TGGTCACGAAATTGGCGATACGATTAAAATCACCTATTATCGTGGTAAAGATAAACAAACCACTGACATTAAATTAAGCA
AGTCAACACAAGATTTAGAAAACAACTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (277-372)

• Trypsin-like peptidase domain (Trypsin_2) (89-234)

3D structure

• AlphaFold DB: A0A2L0D730

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	67.112	97.906	0.657
htrA	Streptococcus pneumoniae Rx1	64.183	91.361	0.586
htrA	Streptococcus pneumoniae D39	64.183	91.361	0.586
htrA	Streptococcus pneumoniae R6	64.183	91.361	0.586
htrA	Streptococcus pneumoniae TIGR4	64.183	91.361	0.586
htrA	Streptococcus mitis NCTC 12261	64.183	91.361	0.586
htrA	Streptococcus gordonii str. Challis substr. CH1	58.839	99.215	0.584