Detailed information NTG0262349

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: C0J00_RS04920
• Genome accession: NZ_CP025536
• Coordinates: 947167..948009 (+)
• Length: 280 a.a.
• NCBI ID: WP_104967818.1
• Uniprot ID: A0A2L0D4I4
• Organism: Streptococcus pluranimalium strain TH11417
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 942167..953009

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C0J00_RS04890 (C0J00_04895)	-	942378..942611 (+)	234	WP_104967814.1	DNA-binding protein	-
C0J00_RS04895 (C0J00_04900)	-	942686..944192 (+)	1507	Protein_916	tyrosine-type recombinase/integrase	-
C0J00_RS04900 (C0J00_04905)	ylqF	944283..945134 (+)	852	WP_104967815.1	ribosome biogenesis GTPase YlqF	-
C0J00_RS04905 (C0J00_04910)	-	945121..945906 (+)	786	WP_104967816.1	ribonuclease HII	-
C0J00_RS04910 (C0J00_04915)	-	945899..946552 (+)	654	WP_407697195.1	GNAT family N-acetyltransferase	-
C0J00_RS04915 (C0J00_04920)	-	946549..947097 (+)	549	WP_104967817.1	sugar O-acetyltransferase	-
C0J00_RS04920 (C0J00_04925)	dprA	947167..948009 (+)	843	WP_104967818.1	DNA-processing protein DprA	Machinery gene
C0J00_RS04925 (C0J00_04930)	topA	948132..950267 (+)	2136	WP_104967819.1	type I DNA topoisomerase	-
C0J00_RS04930 (C0J00_04935)	-	950579..951571 (+)	993	WP_104967820.1	D-2-hydroxyacid dehydrogenase	-
C0J00_RS04935 (C0J00_04940)	-	951701..952369 (+)	669	WP_104967821.1	SatD family protein	-

Sequence

Protein

• Length: 280 a.a.
• Molecular weight: 31135.98 Da
• Isoelectric Point: 7.6337

>NTDB_id=262349 C0J00_RS04920 WP_104967818.1 947167..948009(+) (dprA) [Streptococcus pluranimalium strain TH11417]
MNNFELYKLKKAGLSNQHILNILDYEAKYQKSLSLRDRAVVSKCSNPVVFMEHYKNLDSKTLRQEFLTFPSISILDDDYP
LELKEIYNPPVLLFYKGNIDLLEKPKLAVVGARKCSEIGTKSIQKIITELENRFVIVSGLARGIDTAAHLSALKNGGASI
GIIGTGLDVYYPKENQRLQDFMMQNHLVLSEYGPGEQPLKYHFPERNRIIAGLCQGIIVAEAKLRSGSLITCERALEGGR
DVFALPGNILDGKSAGCLQLIQEGAKCITSGFDVLSDYSF

Nucleotide

• Length: 843 bp

>NTDB_id=262349 C0J00_RS04920 WP_104967818.1 947167..948009(+) (dprA) [Streptococcus pluranimalium strain TH11417]
ATGAATAATTTTGAATTGTACAAACTAAAAAAAGCAGGTTTATCTAATCAGCATATCTTAAATATCCTAGATTACGAAGC
TAAATATCAAAAATCCTTATCCCTTAGAGACCGTGCAGTAGTATCTAAATGTTCTAATCCAGTTGTTTTTATGGAGCATT
ATAAAAACTTGGATAGTAAGACCTTACGTCAAGAATTTCTAACCTTTCCTAGCATTTCCATCTTAGATGATGATTATCCT
TTGGAACTCAAGGAAATCTATAATCCACCTGTACTTTTGTTTTATAAAGGAAATATTGATCTGCTTGAAAAACCAAAACT
AGCAGTGGTTGGTGCTAGAAAATGTAGTGAGATAGGGACAAAGTCTATTCAGAAGATTATCACGGAACTGGAGAATCGTT
TTGTGATTGTTAGCGGATTGGCGCGTGGTATTGATACGGCAGCTCATTTGTCTGCACTTAAAAATGGAGGAGCTAGTATT
GGGATTATTGGAACAGGTCTTGATGTTTACTATCCCAAAGAAAATCAACGGTTACAGGATTTTATGATGCAAAACCATTT
GGTCCTTTCAGAGTATGGTCCTGGTGAACAACCACTTAAATATCACTTTCCAGAGCGAAATCGTATTATTGCAGGGCTTT
GTCAGGGAATTATTGTCGCTGAAGCTAAATTGCGCTCAGGAAGTTTAATCACTTGTGAGCGCGCATTAGAAGGAGGGAGA
GATGTTTTTGCACTTCCGGGCAATATTTTAGATGGCAAGTCCGCTGGTTGTTTACAATTGATTCAAGAGGGTGCAAAGTG
CATTACATCGGGATTTGATGTCTTGAGTGATTACTCATTTTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (72-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

3D structure

• AlphaFold DB: A0A2L0D4I4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	71.786	100	0.718
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	66.071	100	0.661
dprA/cilB/dalA	Streptococcus pneumoniae D39	66.071	100	0.661
dprA/cilB/dalA	Streptococcus pneumoniae R6	66.071	100	0.661
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	66.071	100	0.661
dprA/cilB/dalA	Streptococcus mitis SK321	66.071	100	0.661
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	65.714	100	0.657
dprA	Lactococcus lactis subsp. cremoris KW2	57.5	100	0.575
dprA	Legionella pneumophila strain ERS1305867	42.437	85	0.361