Detailed information NTG0261114

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: CRH08_RS06060
• Genome accession: NZ_CP025419
• Coordinates: 1172788..1173630 (-)
• Length: 280 a.a.
• NCBI ID: WP_009909860.1
• Uniprot ID: A0A075SDJ3
• Organism: Streptococcus suis strain SH0104
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1167788..1178630

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CRH08_RS06035	-	1167846..1168670 (-)	825	WP_009909851.1	replication initiator protein A	-
CRH08_RS06040	-	1168667..1168840 (-)	174	WP_006738653.1	hypothetical protein	-
CRH08_RS06045	rplL	1169100..1169465 (-)	366	WP_002936483.1	50S ribosomal protein L7/L12	-
CRH08_RS06050	rplJ	1169531..1170025 (-)	495	WP_002936486.1	50S ribosomal protein L10	-
CRH08_RS06055	topA	1170602..1172695 (-)	2094	WP_024409355.1	type I DNA topoisomerase	-
CRH08_RS06060	dprA	1172788..1173630 (-)	843	WP_009909860.1	DNA-processing protein DprA	Machinery gene
CRH08_RS06065	-	1173689..1174246 (-)	558	WP_009909862.1	sugar O-acetyltransferase	-
CRH08_RS06070	-	1174257..1174517 (-)	261	WP_009909865.1	metal-sensitive transcriptional regulator	-
CRH08_RS06075	-	1174636..1174959 (+)	324	WP_002936495.1	rhodanese-like domain-containing protein	-
CRH08_RS06080	-	1174956..1176608 (+)	1653	WP_002936496.1	FAD-dependent oxidoreductase	-
CRH08_RS06085	-	1176716..1177267 (+)	552	WP_002936497.1	DUF1836 domain-containing protein	-
CRH08_RS06090	-	1177257..1177907 (+)	651	WP_002936498.1	hemolysin III family protein	-

Sequence

Protein

• Length: 280 a.a.
• Molecular weight: 31260.13 Da
• Isoelectric Point: 8.6529

>NTDB_id=261114 CRH08_RS06060 WP_009909860.1 1172788..1173630(-) (dprA) [Streptococcus suis strain SH0104]
MNNFELFKWKKAGLTNLNVNKVLAYQEKHGKKLTLRNVAVVSECKNPVLFMENYKNLDTKACREEFNKYPSFSILDDIYP
LALKQIYNPPVLLFYQGDLELLEKSKLAVVGTRNASKNGVQSVQKIIKELNNRFVIVSGLARGIDTAAHIASLKNGGQTI
AVIGTGLDKIYPKENRELQTYIGKHHLVLTEYGPGTDPLKYHFPERNRIIAGLVEGLVVCEAKMRSGSLITCERALEEGR
EVYAIPGSIMDGKSDGCHHLIQEGAKCVTSGLDIISEYQF

Nucleotide

• Length: 843 bp

>NTDB_id=261114 CRH08_RS06060 WP_009909860.1 1172788..1173630(-) (dprA) [Streptococcus suis strain SH0104]
ATGAATAATTTTGAATTGTTTAAATGGAAAAAAGCGGGTTTGACCAATCTTAATGTGAACAAAGTTTTGGCCTATCAAGA
AAAACACGGTAAAAAATTGACCTTGCGAAATGTCGCTGTAGTGTCTGAATGTAAAAATCCAGTTCTATTTATGGAAAATT
ATAAGAATCTAGATACAAAAGCTTGTCGCGAGGAATTTAATAAGTATCCATCATTTTCAATTTTAGATGACATCTATCCT
TTGGCGCTCAAACAGATTTACAATCCACCTGTACTTTTGTTTTATCAAGGGGATTTAGAATTGCTAGAAAAATCAAAGCT
GGCAGTTGTTGGTACACGAAATGCCAGTAAAAATGGCGTTCAGTCTGTTCAGAAGATTATCAAAGAACTCAACAATCGCT
TTGTCATTGTCAGTGGTTTGGCAAGAGGAATTGATACAGCTGCCCATATTGCTAGCCTGAAAAATGGTGGACAAACCATT
GCCGTTATTGGAACAGGTTTGGATAAGATATATCCCAAAGAAAATAGAGAATTACAGACCTACATCGGAAAACATCATTT
GGTTCTGACTGAATATGGACCAGGTACAGACCCTCTCAAGTACCATTTCCCAGAACGCAATCGCATAATAGCTGGTTTGG
TGGAAGGATTGGTAGTCTGTGAAGCTAAGATGCGGTCTGGTAGCCTCATTACCTGTGAACGTGCCTTGGAAGAAGGAAGA
GAAGTCTATGCTATTCCAGGTTCCATTATGGACGGAAAATCAGATGGTTGTCATCATCTGATTCAAGAGGGAGCAAAGTG
CGTTACATCCGGCTTGGACATCATTTCAGAGTATCAATTTTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (73-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-61)

3D structure

• AlphaFold DB: A0A075SDJ3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	69.286	100	0.693
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	63.571	100	0.636
dprA/cilB/dalA	Streptococcus pneumoniae D39	63.571	100	0.636
dprA/cilB/dalA	Streptococcus pneumoniae R6	63.571	100	0.636
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	63.571	100	0.636
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	63.571	100	0.636
dprA/cilB/dalA	Streptococcus mitis SK321	63.571	100	0.636
dprA	Lactococcus lactis subsp. cremoris KW2	60.357	100	0.604
dprA	Bacillus subtilis subsp. subtilis str. 168	51.741	71.786	0.371
dprA	Legionella pneumophila strain ERS1305867	41.7	88.214	0.368