Detailed information
Bioinformatically predicted
Overview
| Name | stkP | Type | Regulator |
| Locus tag | CRH08_RS02280 | Genome accession | NZ_CP025419 |
| Coordinates | 429253..431247 (+) | Length | 664 a.a. |
| NCBI ID | WP_009909429.1 | Uniprot ID | - |
| Organism | Streptococcus suis strain SH0104 | ||
| Function | require for competence development; phosphorylate ComE (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 409027..479621 | 429253..431247 | within | 0 |
Gene organization within MGE regions
Location: 409027..479621
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| CRH08_RS02180 | - | 409027..410700 (+) | 1674 | WP_009909409.1 | ABC transporter ATP-binding protein | - |
| CRH08_RS02185 | - | 410697..411530 (+) | 834 | WP_004194181.1 | energy-coupling factor transporter transmembrane component T | - |
| CRH08_RS02190 | - | 411690..411893 (+) | 204 | WP_004194179.1 | cold-shock protein | - |
| CRH08_RS02195 | rsmG | 412083..412796 (-) | 714 | WP_004194177.1 | 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG | - |
| CRH08_RS02200 | pbp1a | 412855..415029 (-) | 2175 | WP_004194174.1 | penicillin-binding protein PBP1A | - |
| CRH08_RS02205 | recU | 415010..415627 (-) | 618 | WP_004194173.1 | Holliday junction resolvase RecU | - |
| CRH08_RS02210 | - | 415693..416232 (+) | 540 | WP_004194171.1 | DUF1273 domain-containing protein | - |
| CRH08_RS02215 | gpsB | 416300..416635 (+) | 336 | WP_004194167.1 | cell division regulator GpsB | - |
| CRH08_RS02225 | - | 417192..418358 (+) | 1167 | WP_004194163.1 | class I SAM-dependent RNA methyltransferase | - |
| CRH08_RS02230 | - | 418368..419822 (+) | 1455 | WP_004194161.1 | cell division site-positioning protein MapZ family protein | - |
| CRH08_RS02235 | - | 420040..420522 (-) | 483 | WP_004194159.1 | S-ribosylhomocysteine lyase | - |
| CRH08_RS02240 | - | 420650..422263 (+) | 1614 | WP_009909417.1 | ribonuclease Y | - |
| CRH08_RS02245 | gmk | 422411..423037 (+) | 627 | WP_004194155.1 | guanylate kinase | - |
| CRH08_RS02250 | rpoZ | 423061..423375 (+) | 315 | WP_004194153.1 | DNA-directed RNA polymerase subunit omega | - |
| CRH08_RS02260 | - | 423719..426109 (+) | 2391 | WP_004194151.1 | primosomal protein N' | - |
| CRH08_RS02265 | fmt | 426240..427178 (+) | 939 | WP_009909423.1 | methionyl-tRNA formyltransferase | - |
| CRH08_RS02270 | rsmB | 427165..428478 (+) | 1314 | WP_074412645.1 | 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB | - |
| CRH08_RS02275 | - | 428516..429253 (+) | 738 | WP_012774983.1 | Stp1/IreP family PP2C-type Ser/Thr phosphatase | - |
| CRH08_RS02280 | stkP | 429253..431247 (+) | 1995 | WP_009909429.1 | Stk1 family PASTA domain-containing Ser/Thr kinase | Regulator |
| CRH08_RS02285 | liaF | 431704..432363 (+) | 660 | WP_226964025.1 | cell wall-active antibiotics response protein LiaF | - |
| CRH08_RS02290 | - | 432360..433376 (+) | 1017 | WP_002937028.1 | sensor histidine kinase | - |
| CRH08_RS02295 | - | 433348..433989 (+) | 642 | WP_002937025.1 | response regulator transcription factor | - |
| CRH08_RS02300 | - | 434039..435439 (+) | 1401 | WP_002937018.1 | Cof-type HAD-IIB family hydrolase | - |
| CRH08_RS02305 | - | 435441..435812 (+) | 372 | WP_002937017.1 | S1 RNA-binding domain-containing protein | - |
| CRH08_RS02310 | cysK | 435839..436765 (-) | 927 | WP_002937015.1 | cysteine synthase A | - |
| CRH08_RS02315 | - | 436995..438152 (-) | 1158 | WP_024409220.1 | site-specific integrase | - |
| CRH08_RS02320 | - | 438349..439080 (-) | 732 | WP_013730164.1 | hypothetical protein | - |
| CRH08_RS02325 | - | 439128..439511 (-) | 384 | WP_013730165.1 | ImmA/IrrE family metallo-endopeptidase | - |
| CRH08_RS02330 | - | 439518..440066 (-) | 549 | WP_226960627.1 | helix-turn-helix transcriptional regulator | - |
| CRH08_RS02335 | - | 440083..440283 (+) | 201 | WP_002937001.1 | helix-turn-helix transcriptional regulator | - |
| CRH08_RS02340 | - | 440353..440679 (+) | 327 | WP_013730166.1 | hypothetical protein | - |
| CRH08_RS02345 | - | 440753..441007 (+) | 255 | WP_013730167.1 | hypothetical protein | - |
| CRH08_RS02350 | - | 441048..441296 (+) | 249 | WP_013730168.1 | hypothetical protein | - |
| CRH08_RS11545 | - | 441286..441438 (+) | 153 | WP_022540561.1 | hypothetical protein | - |
| CRH08_RS02355 | - | 441443..441784 (+) | 342 | WP_013730169.1 | hypothetical protein | - |
| CRH08_RS02360 | - | 441784..442263 (+) | 480 | WP_013730170.1 | siphovirus Gp157 family protein | - |
| CRH08_RS02365 | - | 442260..442505 (+) | 246 | WP_013730171.1 | hypothetical protein | - |
| CRH08_RS02370 | - | 442486..442950 (+) | 465 | WP_013730172.1 | hypothetical protein | - |
| CRH08_RS02375 | - | 442919..444091 (+) | 1173 | WP_013730173.1 | DEAD/DEAH box helicase family protein | - |
| CRH08_RS02380 | - | 444165..444431 (+) | 267 | WP_226960629.1 | hypothetical protein | - |
| CRH08_RS02385 | - | 444441..445139 (+) | 699 | WP_013730175.1 | ERF family protein | - |
| CRH08_RS02390 | - | 445139..445435 (+) | 297 | WP_022540564.1 | hypothetical protein | - |
| CRH08_RS02395 | ssbA | 445432..445830 (+) | 399 | WP_022540565.1 | single-stranded DNA-binding protein | Machinery gene |
| CRH08_RS02400 | - | 445841..446668 (+) | 828 | WP_013730177.1 | bifunctional DNA primase/polymerase | - |
| CRH08_RS02405 | - | 446652..448031 (+) | 1380 | WP_079253058.1 | virulence-associated E family protein | - |
| CRH08_RS11630 | - | 448388..448543 (+) | 156 | WP_204356746.1 | hypothetical protein | - |
| CRH08_RS02410 | - | 448540..448848 (+) | 309 | WP_013730180.1 | DUF1372 family protein | - |
| CRH08_RS02415 | - | 448850..449065 (+) | 216 | WP_013730181.1 | hypothetical protein | - |
| CRH08_RS02420 | - | 449254..449571 (+) | 318 | WP_044752290.1 | hypothetical protein | - |
| CRH08_RS02425 | - | 449644..450078 (+) | 435 | WP_002937915.1 | DUF1492 domain-containing protein | - |
| CRH08_RS02430 | - | 450175..450522 (+) | 348 | WP_013730183.1 | HNH endonuclease signature motif containing protein | - |
| CRH08_RS02435 | - | 450614..450973 (+) | 360 | WP_024409219.1 | hypothetical protein | - |
| CRH08_RS02440 | - | 450970..452235 (+) | 1266 | WP_013730185.1 | phage portal protein | - |
| CRH08_RS11635 | - | 452228..453448 (+) | 1221 | WP_013730186.1 | hypothetical protein | - |
| CRH08_RS02450 | - | 453471..453686 (+) | 216 | WP_162632265.1 | hypothetical protein | - |
| CRH08_RS02455 | - | 453888..455090 (-) | 1203 | WP_112493929.1 | IS110 family transposase | - |
| CRH08_RS11755 | - | 455422..455685 (-) | 264 | Protein_439 | IS110 family transposase | - |
| CRH08_RS11760 | - | 455994..456278 (+) | 285 | Protein_440 | ISL3 family transposase | - |
| CRH08_RS02465 | - | 456805..457443 (-) | 639 | WP_009909540.1 | MBL fold metallo-hydrolase | - |
| CRH08_RS02470 | - | 457560..460019 (+) | 2460 | WP_226960630.1 | bifunctional DnaQ family exonuclease/ATP-dependent helicase | - |
| CRH08_RS02475 | proB | 460181..461257 (+) | 1077 | WP_013730270.1 | glutamate 5-kinase | - |
| CRH08_RS02480 | - | 461322..462560 (+) | 1239 | WP_009909544.1 | glutamate-5-semialdehyde dehydrogenase | - |
| CRH08_RS02485 | proC | 462570..463355 (+) | 786 | WP_009909545.1 | pyrroline-5-carboxylate reductase | - |
| CRH08_RS02490 | - | 463378..463782 (-) | 405 | WP_013730271.1 | TetR/AcrR family transcriptional regulator | - |
| CRH08_RS02495 | - | 463909..464760 (+) | 852 | WP_013730272.1 | DegV family protein | - |
| CRH08_RS02500 | - | 464859..466118 (-) | 1260 | WP_112493930.1 | PLP-dependent aminotransferase family protein | - |
| CRH08_RS02505 | yaaA | 466240..466974 (+) | 735 | WP_012775019.1 | peroxide stress protein YaaA | - |
| CRH08_RS02510 | - | 467079..468524 (+) | 1446 | WP_024409273.1 | LCP family protein | - |
| CRH08_RS02515 | - | 468542..469231 (+) | 690 | WP_024409274.1 | Wzz/FepE/Etk N-terminal domain-containing protein | - |
| CRH08_RS02520 | - | 469241..469918 (+) | 678 | WP_024409275.1 | tyrosine-protein kinase | - |
| CRH08_RS02525 | cps4B | 469957..470688 (+) | 732 | WP_002936359.1 | capsular polysaccharide biosynthesis protein Cps4B | - |
| CRH08_RS02530 | - | 470713..472092 (+) | 1380 | WP_002936357.1 | sugar transferase | - |
| CRH08_RS02535 | - | 472131..473300 (+) | 1170 | WP_002936354.1 | glycosyltransferase family 1 protein | - |
| CRH08_RS02540 | - | 473304..474461 (+) | 1158 | WP_002936352.1 | glycosyltransferase family 4 protein | - |
| CRH08_RS02545 | - | 474775..476220 (+) | 1446 | WP_009909569.1 | glycosyltransferase family 2 protein | - |
| CRH08_RS02550 | wzy | 476288..477487 (+) | 1200 | WP_009909570.1 | oligosaccharide repeat unit polymerase Wzy | - |
| CRH08_RS02555 | - | 477626..478624 (+) | 999 | WP_002936347.1 | glycosyltransferase family 2 protein | - |
| CRH08_RS02560 | - | 478617..479621 (+) | 1005 | WP_009909571.1 | glycosyltransferase family 2 protein | - |
Sequence
Protein
Download Length: 664 a.a. Molecular weight: 71226.76 Da Isoelectric Point: 6.5350
>NTDB_id=261105 CRH08_RS02280 WP_009909429.1 429253..431247(+) (stkP) [Streptococcus suis strain SH0104]
MIQIGKIFAGRYRIVRQIGRGGMADVYLARDLILDGEEVAVKVLRTNYQTDQIAIQRFQREARAMAELDHPNIVRISDIG
EEDGQQYLAMEYVNGLDLKRYIKENAPLSNDVAVRIMGQILLAMRMAHTRGIVHRDLKPQNVLLTSNGVAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIILFEMLTGRIPYDGDSAVTIALQHFQKPLPSVREENANVP
QALENVVLKATAKKLNERYKSVAEMYADLASALSMDRQNEPRVELEGNKVDTKTLPKLSQANVETKVPHTNSSAQVSATD
KGSGKKEVAKSGNKPVSKPRPGIRTRYKVLIGAILLTVIAAGLMFFNAPRTVTVPDVSGQTVEKATEMIEVAGLEVGNIT
EEATATVDEGLVIRTSPAAKTTRRQGSKIDIVVATAALASIPDVVDKESDTARQELEALGFQVTIKEEYSEKVAQGLVIK
TDPGANSSAEKGAKITLYVSKGVAPQVVPNVVGKSQENATQILQTAGFSIGTITQEYSSSVTAGQVISTDPVANTELAKG
SIINLVISKGKELIMPDLTSGNYTYSQARSQLQALGVNAESIEKQEDRSYYSTTSDIVIGQYPAAGATIDGTVTLYVSVA
STRTSSDSSAGSSTSTSTSTGSGQ
MIQIGKIFAGRYRIVRQIGRGGMADVYLARDLILDGEEVAVKVLRTNYQTDQIAIQRFQREARAMAELDHPNIVRISDIG
EEDGQQYLAMEYVNGLDLKRYIKENAPLSNDVAVRIMGQILLAMRMAHTRGIVHRDLKPQNVLLTSNGVAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIILFEMLTGRIPYDGDSAVTIALQHFQKPLPSVREENANVP
QALENVVLKATAKKLNERYKSVAEMYADLASALSMDRQNEPRVELEGNKVDTKTLPKLSQANVETKVPHTNSSAQVSATD
KGSGKKEVAKSGNKPVSKPRPGIRTRYKVLIGAILLTVIAAGLMFFNAPRTVTVPDVSGQTVEKATEMIEVAGLEVGNIT
EEATATVDEGLVIRTSPAAKTTRRQGSKIDIVVATAALASIPDVVDKESDTARQELEALGFQVTIKEEYSEKVAQGLVIK
TDPGANSSAEKGAKITLYVSKGVAPQVVPNVVGKSQENATQILQTAGFSIGTITQEYSSSVTAGQVISTDPVANTELAKG
SIINLVISKGKELIMPDLTSGNYTYSQARSQLQALGVNAESIEKQEDRSYYSTTSDIVIGQYPAAGATIDGTVTLYVSVA
STRTSSDSSAGSSTSTSTSTGSGQ
Nucleotide
Download Length: 1995 bp
>NTDB_id=261105 CRH08_RS02280 WP_009909429.1 429253..431247(+) (stkP) [Streptococcus suis strain SH0104]
ATGATTCAAATCGGTAAGATCTTTGCCGGTCGGTATCGAATCGTTCGGCAAATTGGTCGAGGCGGTATGGCAGATGTTTA
CCTAGCAAGAGATTTGATTTTAGATGGAGAAGAGGTTGCTGTTAAAGTTCTTCGGACCAACTATCAGACAGATCAAATTG
CTATCCAGCGTTTTCAACGTGAAGCGCGTGCCATGGCAGAACTTGACCATCCCAATATCGTTCGTATTTCGGACATCGGT
GAAGAAGATGGTCAACAGTATCTGGCTATGGAATATGTCAATGGCCTCGATTTAAAACGTTATATAAAAGAAAATGCACC
ACTTTCCAACGATGTTGCGGTGCGAATTATGGGACAGATTCTCCTTGCTATGCGCATGGCGCACACGAGAGGAATTGTCC
ATCGAGATTTGAAACCTCAGAACGTCCTTTTGACTTCCAATGGAGTCGCTAAAGTAACAGACTTTGGTATTGCAGTTGCC
TTTGCTGAAACGAGTTTGACACAAACCAACTCCATGTTGGGTTCTGTTCACTATCTTTCACCTGAGCAGGCGCGTGGTTC
GAAAGCGACCATTCAAAGTGATATTTATGCGATGGGAATCATCCTTTTTGAAATGTTGACGGGTCGCATTCCCTATGATG
GAGACAGTGCTGTGACGATCGCTCTTCAGCATTTCCAAAAACCTCTCCCATCTGTTAGAGAAGAGAATGCCAACGTACCT
CAGGCCTTAGAAAATGTTGTACTAAAAGCAACGGCAAAAAAATTAAACGAGCGCTATAAGTCGGTTGCAGAAATGTATGC
AGATTTAGCTTCGGCTCTATCCATGGATCGTCAGAATGAACCCAGGGTTGAACTAGAAGGGAACAAGGTTGATACAAAAA
CCTTGCCGAAACTCTCCCAAGCCAATGTTGAAACGAAAGTACCGCATACAAACAGTTCTGCTCAAGTTTCTGCGACGGAT
AAGGGGTCTGGTAAGAAAGAAGTGGCGAAGTCGGGAAATAAGCCTGTTTCAAAACCAAGGCCAGGCATACGTACACGCTA
CAAAGTCTTGATAGGAGCTATTTTGTTAACAGTCATAGCGGCTGGACTCATGTTTTTCAACGCTCCACGAACAGTTACAG
TCCCTGATGTATCTGGTCAAACCGTTGAAAAAGCTACAGAAATGATTGAAGTGGCAGGATTGGAAGTTGGAAATATCACA
GAAGAAGCGACAGCGACTGTAGATGAAGGCTTGGTAATACGGACCTCTCCGGCTGCAAAGACGACCAGACGTCAAGGGAG
TAAGATTGATATTGTAGTAGCAACGGCTGCGCTGGCATCTATTCCAGATGTGGTGGATAAGGAGTCTGATACTGCGCGGC
AGGAATTGGAGGCCCTTGGTTTCCAAGTGACAATAAAAGAAGAATATAGCGAAAAAGTTGCCCAAGGACTCGTTATCAAA
ACAGATCCAGGAGCAAATAGTTCTGCTGAGAAGGGTGCAAAAATTACCCTTTACGTTTCCAAAGGAGTGGCGCCACAAGT
TGTTCCAAACGTTGTTGGAAAAAGTCAGGAGAATGCTACTCAAATTCTTCAGACAGCAGGCTTCAGCATTGGAACCATTA
CTCAGGAATATAGCTCATCTGTTACTGCAGGTCAGGTTATCAGCACAGATCCCGTTGCCAATACAGAGTTGGCAAAAGGT
TCTATCATCAATCTAGTTATTTCAAAAGGAAAAGAATTGATTATGCCTGATTTAACATCTGGCAATTACACCTATTCACA
GGCGCGTAGTCAATTACAAGCCTTGGGTGTCAATGCGGAAAGTATTGAAAAACAAGAAGATAGAAGCTATTATTCAACGA
CAAGTGACATCGTCATTGGACAATATCCTGCTGCTGGAGCAACAATTGATGGAACAGTTACCTTGTATGTCTCTGTTGCA
TCAACCAGAACCAGTAGCGATTCTTCAGCAGGAAGTTCCACAAGTACAAGTACTTCAACAGGTAGCGGACAATAA
ATGATTCAAATCGGTAAGATCTTTGCCGGTCGGTATCGAATCGTTCGGCAAATTGGTCGAGGCGGTATGGCAGATGTTTA
CCTAGCAAGAGATTTGATTTTAGATGGAGAAGAGGTTGCTGTTAAAGTTCTTCGGACCAACTATCAGACAGATCAAATTG
CTATCCAGCGTTTTCAACGTGAAGCGCGTGCCATGGCAGAACTTGACCATCCCAATATCGTTCGTATTTCGGACATCGGT
GAAGAAGATGGTCAACAGTATCTGGCTATGGAATATGTCAATGGCCTCGATTTAAAACGTTATATAAAAGAAAATGCACC
ACTTTCCAACGATGTTGCGGTGCGAATTATGGGACAGATTCTCCTTGCTATGCGCATGGCGCACACGAGAGGAATTGTCC
ATCGAGATTTGAAACCTCAGAACGTCCTTTTGACTTCCAATGGAGTCGCTAAAGTAACAGACTTTGGTATTGCAGTTGCC
TTTGCTGAAACGAGTTTGACACAAACCAACTCCATGTTGGGTTCTGTTCACTATCTTTCACCTGAGCAGGCGCGTGGTTC
GAAAGCGACCATTCAAAGTGATATTTATGCGATGGGAATCATCCTTTTTGAAATGTTGACGGGTCGCATTCCCTATGATG
GAGACAGTGCTGTGACGATCGCTCTTCAGCATTTCCAAAAACCTCTCCCATCTGTTAGAGAAGAGAATGCCAACGTACCT
CAGGCCTTAGAAAATGTTGTACTAAAAGCAACGGCAAAAAAATTAAACGAGCGCTATAAGTCGGTTGCAGAAATGTATGC
AGATTTAGCTTCGGCTCTATCCATGGATCGTCAGAATGAACCCAGGGTTGAACTAGAAGGGAACAAGGTTGATACAAAAA
CCTTGCCGAAACTCTCCCAAGCCAATGTTGAAACGAAAGTACCGCATACAAACAGTTCTGCTCAAGTTTCTGCGACGGAT
AAGGGGTCTGGTAAGAAAGAAGTGGCGAAGTCGGGAAATAAGCCTGTTTCAAAACCAAGGCCAGGCATACGTACACGCTA
CAAAGTCTTGATAGGAGCTATTTTGTTAACAGTCATAGCGGCTGGACTCATGTTTTTCAACGCTCCACGAACAGTTACAG
TCCCTGATGTATCTGGTCAAACCGTTGAAAAAGCTACAGAAATGATTGAAGTGGCAGGATTGGAAGTTGGAAATATCACA
GAAGAAGCGACAGCGACTGTAGATGAAGGCTTGGTAATACGGACCTCTCCGGCTGCAAAGACGACCAGACGTCAAGGGAG
TAAGATTGATATTGTAGTAGCAACGGCTGCGCTGGCATCTATTCCAGATGTGGTGGATAAGGAGTCTGATACTGCGCGGC
AGGAATTGGAGGCCCTTGGTTTCCAAGTGACAATAAAAGAAGAATATAGCGAAAAAGTTGCCCAAGGACTCGTTATCAAA
ACAGATCCAGGAGCAAATAGTTCTGCTGAGAAGGGTGCAAAAATTACCCTTTACGTTTCCAAAGGAGTGGCGCCACAAGT
TGTTCCAAACGTTGTTGGAAAAAGTCAGGAGAATGCTACTCAAATTCTTCAGACAGCAGGCTTCAGCATTGGAACCATTA
CTCAGGAATATAGCTCATCTGTTACTGCAGGTCAGGTTATCAGCACAGATCCCGTTGCCAATACAGAGTTGGCAAAAGGT
TCTATCATCAATCTAGTTATTTCAAAAGGAAAAGAATTGATTATGCCTGATTTAACATCTGGCAATTACACCTATTCACA
GGCGCGTAGTCAATTACAAGCCTTGGGTGTCAATGCGGAAAGTATTGAAAAACAAGAAGATAGAAGCTATTATTCAACGA
CAAGTGACATCGTCATTGGACAATATCCTGCTGCTGGAGCAACAATTGATGGAACAGTTACCTTGTATGTCTCTGTTGCA
TCAACCAGAACCAGTAGCGATTCTTCAGCAGGAAGTTCCACAAGTACAAGTACTTCAACAGGTAGCGGACAATAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| stkP | Streptococcus pneumoniae TIGR4 |
52.03 |
100 |
0.521 |
| stkP | Streptococcus pneumoniae D39 |
52.03 |
100 |
0.521 |
| stkP | Streptococcus pneumoniae R6 |
52.03 |
100 |
0.521 |
| stkP | Streptococcus pneumoniae Rx1 |
51.88 |
100 |
0.52 |
| stkP/pknB | Streptococcus salivarius strain HSISS4 |
51.171 |
90.06 |
0.461 |
| pknB | Streptococcus mutans UA159 |
54.529 |
81.476 |
0.444 |