Detailed information NTG0261001

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: CR922_RS07950
• Genome accession: NZ_CP025400
• Coordinates: 1495712..1496611 (-)
• Length: 299 a.a.
• NCBI ID: WP_011226854.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain EPS
• Function: activate transcription of comX; activate transcription of comS (predicted from homology) Competence regulation

Genomic Context

Location: 1490712..1501611

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CR922_RS07915	-	1490713..1491228 (-)	516	WP_011226861.1	AmiS/UreI family transporter	-
CR922_RS10440	-	1491633..1492004 (+)	372	WP_231108754.1	hypothetical protein	-
CR922_RS10445	-	1492770..1493054 (+)	285	WP_231108755.1	hypothetical protein	-
CR922_RS07925	-	1493022..1493333 (-)	312	WP_011226857.1	DUF805 domain-containing protein	-
CR922_RS07930	-	1493441..1494009 (-)	569	Protein_1481	ATP-binding cassette domain-containing protein	-
CR922_RS07945	-	1494295..1495536 (-)	1242	Protein_1482	ABC transporter transmembrane domain-containing protein	-
CR922_RS07950	comR	1495712..1496611 (-)	900	WP_011226854.1	helix-turn-helix domain-containing protein	Regulator
CR922_RS07955	-	1496806..1497456 (-)	651	WP_011226853.1	phosphatase PAP2 family protein	-
CR922_RS07960	-	1497459..1498016 (-)	558	WP_002949523.1	ECF transporter S component	-
CR922_RS07965	-	1498329..1498868 (-)	540	WP_372585740.1	tRNA (cytidine(34)-2'-O)-methyltransferase	-
CR922_RS07970	trkA	1499127..1500476 (+)	1350	WP_011225444.1	Trk system potassium transporter TrkA	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35317.79 Da
• Isoelectric Point: 5.1073

>NTDB_id=261001 CR922_RS07950 WP_011226854.1 1495712..1496611(-) (comR) [Streptococcus thermophilus strain EPS]
MNIKDSIGLRIKTERERQQMSREVLCLDGAELTVRQLIRIEKGESLPSLDRLSYIAKRLGKSMTELLDQDNITIPDEYYE
MKNRLIKFPTYRNPDRIKSKLTLIEEVYEKFFDILPEEELLTLDILENILSFTSWEESPKVEEIYEDLFEQVKRKRKFST
NDLLIIDYYFFHLYGRKQYDKKLFERIIKRVLNQEIWTDDVYNIVLFNDLMAIAALKIFHNSFSDFLTVVDKALAVIEKS
QLYSYKPSVFVLKAKYELLHKENKKEAAENYDKAIMFASVLEDSVLEESIKAGKLADGL

Nucleotide

• Length: 900 bp

>NTDB_id=261001 CR922_RS07950 WP_011226854.1 1495712..1496611(-) (comR) [Streptococcus thermophilus strain EPS]
TTGAACATAAAAGACAGCATTGGACTAAGAATCAAAACTGAGCGTGAACGCCAACAGATGTCACGTGAAGTGCTATGTTT
AGATGGTGCGGAATTGACTGTTCGCCAGTTAATTCGTATTGAAAAGGGGGAGTCTCTCCCGTCTTTAGATAGATTATCGT
ATATTGCTAAACGTTTAGGAAAAAGTATGACAGAGTTATTGGATCAAGACAATATTACCATTCCTGACGAATATTATGAA
ATGAAGAATCGTTTGATTAAGTTTCCAACGTACAGAAACCCTGACAGAATAAAGTCTAAACTTACTTTGATTGAGGAAGT
CTATGAGAAATTTTTTGATATTCTTCCAGAAGAAGAATTATTAACTCTAGACATTCTCGAAAATATATTGAGTTTTACTA
GCTGGGAGGAGAGTCCAAAAGTTGAGGAGATATATGAAGACTTGTTTGAACAAGTCAAAAGGAAGAGGAAATTCTCAACT
AACGATTTATTAATCATTGACTATTATTTCTTTCATCTTTATGGGAGAAAACAGTATGACAAAAAACTATTTGAAAGAAT
TATAAAGAGAGTATTAAATCAGGAAATTTGGACAGATGATGTTTACAATATTGTTTTATTTAATGATTTGATGGCTATTG
CTGCTTTAAAGATTTTTCACAATTCCTTCTCAGACTTCTTAACAGTTGTGGATAAAGCCTTAGCTGTCATAGAAAAATCA
CAATTATATAGCTACAAGCCTAGTGTTTTTGTACTTAAGGCTAAATATGAACTTCTGCATAAAGAAAACAAGAAAGAGGC
TGCAGAGAATTATGATAAGGCCATAATGTTTGCTTCCGTTTTGGAAGACTCGGTTTTAGAGGAAAGTATAAAGGCAGGAA
AATTGGCAGATGGTTTATAG

Domains

Predicted by InterproScan.

• Helix-turn-helix (HTH_3) (11-66)

• ComR tetratricopeptide (ComR_TPR) (75-292)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus thermophilus LMG 18311	99.666	100	0.997
comR	Streptococcus thermophilus LMD-9	98.997	100	0.99
comR	Streptococcus salivarius strain HSISS4	94.983	100	0.95
comR	Streptococcus salivarius SK126	94.314	100	0.943
comR/comR1	Streptococcus sobrinus strain NIDR 6715-7	42.14	100	0.421
comR/comR2	Streptococcus sobrinus strain NIDR 6715-7	42.14	100	0.421