Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   CR922_RS03950 Genome accession   NZ_CP025400
Coordinates   747738..748445 (+) Length   235 a.a.
NCBI ID   WP_101361271.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain EPS     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 742738..753445
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CR922_RS03920 - 743014..743202 (+) 189 WP_011227277.1 DNA-directed RNA polymerase subunit beta -
  CR922_RS03925 endA 743264..744145 (+) 882 WP_011226089.1 DNA/RNA non-specific endonuclease Machinery gene
  CR922_RS03930 - 744216..744866 (-) 651 WP_011226088.1 amino acid ABC transporter permease -
  CR922_RS03935 - 744878..745576 (-) 699 WP_011226087.1 amino acid ABC transporter permease -
  CR922_RS03940 - 745594..746427 (-) 834 WP_011227276.1 transporter substrate-binding domain-containing protein -
  CR922_RS03945 - 746439..747206 (-) 768 WP_011227275.1 amino acid ABC transporter ATP-binding protein -
  CR922_RS03950 vicR 747738..748445 (+) 708 WP_101361271.1 response regulator YycF Regulator
  CR922_RS03955 vicK 748438..749778 (+) 1341 WP_101361272.1 cell wall metabolism sensor histidine kinase VicK Regulator
  CR922_RS03960 vicX 749784..750596 (+) 813 WP_011681204.1 MBL fold metallo-hydrolase Regulator
  CR922_RS03965 - 750656..751017 (+) 362 Protein_716 YbaN family protein -
  CR922_RS03970 - 751069..752283 (-) 1215 WP_011227270.1 aminoacyltransferase -
  CR922_RS03975 yidA 752285..753094 (-) 810 WP_011226081.1 sugar-phosphatase -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 27119.08 Da        Isoelectric Point: 5.0130

>NTDB_id=260984 CR922_RS03950 WP_101361271.1 747738..748445(+) (vicR) [Streptococcus thermophilus strain EPS]
MKKILVVDDERTISDIIKFNLTKEGYEVVTAFDGREALEQFEAKKPDLVILDLMLPELDGLEIVKEIRKTSHTPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTETIETAVEESSNSGKQEISIGELIIVPDAFVAKKRGNEVEL
THREFELLFHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKNYD

Nucleotide


Download         Length: 708 bp        

>NTDB_id=260984 CR922_RS03950 WP_101361271.1 747738..748445(+) (vicR) [Streptococcus thermophilus strain EPS]
ATGAAAAAAATTCTAGTTGTTGATGATGAAAGAACAATCTCCGATATCATCAAGTTTAACCTTACTAAGGAGGGTTATGA
AGTGGTTACGGCCTTTGATGGGCGAGAAGCTTTGGAACAATTTGAAGCTAAAAAACCAGACTTGGTTATTCTGGACTTGA
TGTTGCCTGAACTGGATGGTTTGGAAATTGTCAAGGAAATCCGTAAAACGAGCCACACACCGATTATCATGCTTTCAGCT
AAAGATAGTGAGTTTGATAAGGTTATCGGATTAGAAATTGGGGCAGACGACTATGTGACTAAGCCATTTTCTAACCGTGA
ATTGTTGGCACGTATTAAAGCCCACTTGCGTCGTACAGAAACGATTGAAACTGCAGTAGAAGAGAGCTCTAACTCTGGCA
AACAAGAAATTTCAATTGGTGAGTTGATTATTGTTCCGGATGCCTTTGTTGCTAAAAAACGTGGAAACGAAGTTGAGTTG
ACCCACCGTGAATTTGAGTTACTCTTCCATTTGGCAACTCATATGGGACAAGTTATGACGCGTGAACATTTGCTTGAAAC
CGTTTGGGGCTATGACTATTTTGGGGATGTTCGTACTGTGGACGTAACGATTCGTCGTCTGCGTGAAAAAATTGAAGATA
CACCTAGCCGTCCTGAATATATCTTGACGCGTCGTGGTGTCGGTTATTACATGAAGAATTATGACTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-113)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-230)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

84.255

100

0.843
  micA Streptococcus pneumoniae Cp1015

78.97

99.149

0.783
  covR Streptococcus salivarius strain HSISS4

44.872

99.574

0.447
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.022

98.298

0.443
  scnR Streptococcus mutans UA159

38.136

100

0.383

Multiple sequence alignment