Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   CR922_RS03925 Genome accession   NZ_CP025400
Coordinates   743264..744145 (+) Length   293 a.a.
NCBI ID   WP_011226089.1    Uniprot ID   Q5M441
Organism   Streptococcus thermophilus strain EPS     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 738264..749145
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CR922_RS03900 - 739764..740219 (+) 456 WP_041827047.1 DUF4832 domain-containing protein -
  CR922_RS03905 galE 740234..741247 (+) 1014 WP_011227279.1 UDP-glucose 4-epimerase GalE -
  CR922_RS03910 - 741435..741671 (+) 237 WP_002946959.1 DUF1146 family protein -
  CR922_RS03915 murA 741741..743012 (+) 1272 WP_101361270.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  CR922_RS03920 - 743014..743202 (+) 189 WP_011227277.1 DNA-directed RNA polymerase subunit beta -
  CR922_RS03925 endA 743264..744145 (+) 882 WP_011226089.1 DNA/RNA non-specific endonuclease Machinery gene
  CR922_RS03930 - 744216..744866 (-) 651 WP_011226088.1 amino acid ABC transporter permease -
  CR922_RS03935 - 744878..745576 (-) 699 WP_011226087.1 amino acid ABC transporter permease -
  CR922_RS03940 - 745594..746427 (-) 834 WP_011227276.1 transporter substrate-binding domain-containing protein -
  CR922_RS03945 - 746439..747206 (-) 768 WP_011227275.1 amino acid ABC transporter ATP-binding protein -
  CR922_RS03950 vicR 747738..748445 (+) 708 WP_101361271.1 response regulator YycF Regulator

Sequence

Protein


Download         Length: 293 a.a.        Molecular weight: 31757.50 Da        Isoelectric Point: 10.1789

>NTDB_id=260983 CR922_RS03925 WP_011226089.1 743264..744145(+) (endA) [Streptococcus thermophilus strain EPS]
MAKRKTSLTNKQKRQLVTLIIAALIAVLGYLGTSNKLSPDNPIRQVASLVAGKSNKSIKSNGSTNSQSTPQEQLAETVMT
SSVKSQLGNSLEWNGAGAYIINRNKTNLNAKVSSQPYANNQVKTVQGQTVPTVANALLSKATRQYKNRQETGNGSTSWTP
AGWHQVQNLSGEYSHAVDRGHLLGYALIGGLKGFDASTSNPENIAVQTAWANQAYSDSSTGQNYYESLVRKALDKNKRVR
YRVTLIYEGENLIPSGTHLEAKSADGSLEFNVFVPNVQEGITLDYYSGKVTVN

Nucleotide


Download         Length: 882 bp        

>NTDB_id=260983 CR922_RS03925 WP_011226089.1 743264..744145(+) (endA) [Streptococcus thermophilus strain EPS]
ATGGCAAAAAGAAAGACATCTTTGACAAATAAACAGAAACGTCAGTTAGTCACATTAATAATAGCAGCTTTGATAGCTGT
TTTAGGTTACCTAGGAACCAGTAACAAGCTCTCGCCTGATAATCCTATCAGACAAGTAGCAAGCCTAGTTGCAGGGAAAT
CTAACAAATCCATTAAATCTAATGGTTCAACAAATAGTCAGTCTACACCACAAGAGCAGCTTGCTGAGACAGTAATGACT
AGTTCAGTCAAAAGCCAACTGGGTAATTCCTTGGAATGGAATGGAGCTGGGGCCTACATTATTAATAGAAATAAGACGAA
TCTAAATGCTAAGGTATCAAGCCAACCCTATGCTAATAACCAAGTCAAAACGGTTCAAGGACAAACTGTTCCTACAGTTG
CTAATGCCTTATTAAGTAAAGCAACTAGACAGTACAAAAATCGTCAAGAAACAGGGAATGGTTCAACCTCTTGGACACCA
GCTGGATGGCACCAGGTTCAAAATTTATCAGGAGAGTATAGCCATGCCGTAGATAGAGGCCATTTGCTAGGTTATGCACT
GATAGGTGGTTTGAAAGGATTTGATGCCTCGACTTCAAATCCAGAGAATATTGCTGTTCAAACTGCTTGGGCAAATCAAG
CATATAGCGATAGTTCTACAGGCCAAAACTATTATGAAAGCCTAGTACGAAAAGCCCTGGATAAAAACAAACGTGTTCGT
TATCGTGTGACCCTGATTTATGAAGGAGAGAATCTCATTCCATCAGGAACACATCTTGAAGCTAAGTCAGCAGACGGCTC
ACTTGAGTTTAATGTCTTTGTTCCAAATGTACAAGAGGGAATTACACTAGATTACTATTCAGGAAAAGTAACGGTGAATT
GA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(101-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q5M441

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

72.803

81.57

0.594
  endA Streptococcus pneumoniae D39

72.803

81.57

0.594
  endA Streptococcus pneumoniae R6

72.803

81.57

0.594
  endA Streptococcus pneumoniae TIGR4

72.803

81.57

0.594

Multiple sequence alignment