Detailed information NTG0260953

Bioinformatically predicted

Overview

• Name: comGF
• Type: Machinery gene
• Locus tag: DSN71_RS01295
• Genome accession: NZ_CP030845
• Coordinates: 214097..214558 (+)
• Length: 153 a.a.
• NCBI ID: WP_001874812.1
• Uniprot ID: -
• Organism: Streptococcus agalactiae strain S73
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 209097..219558

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DSN71_RS01260 (DSN71_01260)	-	210712..211077 (+)	366	WP_000285373.1	DUF1033 family protein	-
DSN71_RS01270 (DSN71_01270)	comGA	211250..212221 (+)	972	WP_000250805.1	competence type IV pilus ATPase ComGA	Machinery gene
DSN71_RS01275 (DSN71_01275)	comGB	212115..213158 (+)	1044	WP_223295889.1	competence type IV pilus assembly protein ComGB	Machinery gene
DSN71_RS01280 (DSN71_01280)	comGC/cglC	213155..213484 (+)	330	WP_000793380.1	competence type IV pilus major pilin ComGC	Machinery gene
DSN71_RS01285 (DSN71_01285)	comGD	213459..213872 (+)	414	WP_000244261.1	competence type IV pilus minor pilin ComGD	Machinery gene
DSN71_RS01290 (DSN71_01290)	comGE	213844..214143 (+)	300	WP_000234804.1	competence type IV pilus minor pilin ComGE	Machinery gene
DSN71_RS01295 (DSN71_01295)	comGF	214097..214558 (+)	462	WP_001874812.1	competence type IV pilus minor pilin ComGF	Machinery gene
DSN71_RS01300 (DSN71_01300)	comGG	214536..214907 (+)	372	WP_000601104.1	competence type IV pilus minor pilin ComGG	Machinery gene
DSN71_RS01305 (DSN71_01305)	comGH	215022..215996 (+)	975	WP_001008574.1	N-6 DNA methylase	Machinery gene
DSN71_RS01310 (DSN71_01310)	-	216028..217221 (+)	1194	WP_000047534.1	acetate kinase	-
DSN71_RS01315 (DSN71_01315)	-	217373..217579 (+)	207	WP_000798241.1	helix-turn-helix transcriptional regulator	-
DSN71_RS10975 (DSN71_01320)	-	217638..217775 (+)	138	WP_001865900.1	hypothetical protein	-
DSN71_RS01325 (DSN71_01325)	-	217816..218271 (+)	456	WP_000905673.1	hypothetical protein	-
DSN71_RS01330 (DSN71_01330)	-	218340..219005 (+)	666	WP_000008113.1	type II CAAX endopeptidase family protein	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17875.89 Da
• Isoelectric Point: 9.8392

>NTDB_id=260953 DSN71_RS01295 WP_001874812.1 214097..214558(+) (comGF) [Streptococcus agalactiae strain S73]
MKIIRKFCTYQKLRVKAFTLLECLVALVTITGALLVYQGLTKLLAQQIVVMSSSSQSEWVLLTQQLNAEFEGAHLEYLRQ
NKLYLRKQDKIVTFGKSNKDDFRKTGYDGRGYQPMVYGLDNCQMSQTKSMVKLVFYFKDGLKRTFYYDFKEET

Nucleotide

• Length: 462 bp

>NTDB_id=260953 DSN71_RS01295 WP_001874812.1 214097..214558(+) (comGF) [Streptococcus agalactiae strain S73]
TTGAAGATAATAAGGAAATTTTGCACGTATCAAAAGTTAAGGGTTAAAGCATTTACGCTTTTAGAATGTTTGGTAGCATT
GGTTACAATCACAGGAGCTTTACTAGTTTATCAAGGACTGACAAAATTGTTGGCTCAACAGATAGTAGTGATGTCTTCTT
CCAGTCAGTCTGAATGGGTGTTATTAACTCAGCAACTAAATGCAGAATTTGAAGGCGCTCATCTGGAATATTTAAGACAG
AACAAACTTTATTTACGTAAGCAAGATAAGATTGTAACCTTTGGCAAATCTAATAAAGATGATTTCCGTAAGACAGGTTA
TGATGGTCGAGGTTATCAACCAATGGTTTATGGGTTAGACAATTGTCAAATGAGTCAGACCAAAAGTATGGTAAAACTTG
TTTTTTATTTTAAGGACGGGTTAAAAAGGACATTTTACTATGATTTTAAAGAAGAAACTTAA

Domains

Predicted by InterProScan.

• Putative Competence protein ComGF (ComGF) (49-142)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF	Streptococcus mutans UA159	47.887	92.81	0.444
comGF	Streptococcus mutans UA140	47.887	92.81	0.444
comGF/cglF	Streptococcus pneumoniae Rx1	43.165	90.85	0.392
comGF/cglF	Streptococcus pneumoniae D39	43.165	90.85	0.392
comGF/cglF	Streptococcus pneumoniae R6	43.165	90.85	0.392
comGF/cglF	Streptococcus pneumoniae TIGR4	43.165	90.85	0.392
comGF/cglF	Streptococcus mitis SK321	44.03	87.582	0.386
comGF/cglF	Streptococcus mitis NCTC 12261	43.284	87.582	0.379
comGF	Lactococcus lactis subsp. cremoris KW2	40.714	91.503	0.373