Detailed information NTG0025851

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: MGAS9429_RS04905
• Genome accession: NC_008021
• Coordinates: 958167..959003 (+)
• Length: 278 a.a.
• NCBI ID: WP_002989770.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes MGAS9429
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 953167..964003

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MGAS9429_RS04875 (MGAS9429_Spy0996)	-	953649..954089 (+)	441	WP_024623381.1	hypothetical protein	-
MGAS9429_RS04880 (MGAS9429_Spy0997)	-	954139..955050 (-)	912	WP_002989777.1	diacylglycerol/lipid kinase family protein	-
MGAS9429_RS04885 (MGAS9429_Spy0998)	trhA	955167..955817 (-)	651	WP_002984629.1	PAQR family membrane homeostasis protein TrhA	-
MGAS9429_RS04890 (MGAS9429_Spy0999)	-	955814..956254 (-)	441	WP_002989774.1	DUF1836 domain-containing protein	-
MGAS9429_RS04895 (MGAS9429_Spy1000)	ylqF	956473..957321 (+)	849	WP_002984625.1	ribosome biogenesis GTPase YlqF	-
MGAS9429_RS04900 (MGAS9429_Spy1001)	-	957311..958102 (+)	792	WP_002989771.1	ribonuclease HII	-
MGAS9429_RS04905 (MGAS9429_Spy1002)	dprA	958167..959003 (+)	837	WP_002989770.1	DNA-processing protein DprA	Machinery gene
MGAS9429_RS04910 (MGAS9429_Spy1003)	topA	959110..961239 (+)	2130	WP_002989768.1	type I DNA topoisomerase	-
MGAS9429_RS09755	-	961314..962171 (-)	858	Protein_939	LysR family transcriptional regulator	-
MGAS9429_RS04920 (MGAS9429_Spy1006)	-	962211..962777 (+)	567	Protein_940	PTS sugar transporter subunit IIC	-
MGAS9429_RS04925 (MGAS9429_Spy1007)	-	962792..963784 (+)	993	WP_002989762.1	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30956.84 Da
• Isoelectric Point: 8.5841

>NTDB_id=25851 MGAS9429_RS04905 WP_002989770.1 958167..959003(+) (dprA) [Streptococcus pyogenes MGAS9429]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQNLKIEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=25851 MGAS9429_RS04905 WP_002989770.1 958167..959003(+) (dprA) [Streptococcus pyogenes MGAS9429]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAATTTAAAAATAGAATTTAAACAGTTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACGTCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.626	100	0.676
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis SK321	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.432	100	0.604
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367