NTDB

Overview

Name	ciaR	Type	Regulator
Locus tag	DK876_RS05070	Genome accession	NZ_CP030022
Coordinates	1039265..1039936 (-)	Length	223 a.a.
NCBI ID	WP_009909965.1	Uniprot ID	-
Organism	Streptococcus suis strain ISU2714
Function	repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1034265..1044936

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DK876_RS05050 (DK876_05245)	rpsT	1035065..1035313 (+)	249	WP_012027069.1	30S ribosomal protein S20	-
DK876_RS05055 (DK876_05255)	tnpA	1035455..1035919 (-)	465	WP_012775157.1	IS200/IS605-like element ISSsu4 family transposase	-
DK876_RS05060 (DK876_05265)	-	1036333..1037562 (-)	1230	WP_012027071.1	transglutaminase domain-containing protein	-
DK876_RS05065 (DK876_05275)	ciaH	1037893..1039272 (-)	1380	WP_012027074.1	cell wall metabolism sensor histidine kinase WalK	Regulator
DK876_RS05070 (DK876_05280)	ciaR	1039265..1039936 (-)	672	WP_009909965.1	response regulator transcription factor	Regulator
DK876_RS05075 (DK876_05285)	-	1040130..1040510 (-)	381	WP_012027076.1	hypothetical protein	-
DK876_RS05080 (DK876_05290)	-	1040895..1042097 (+)	1203	WP_012775158.1	IS110 family transposase	-
DK876_RS05085 (DK876_05295)	phoU	1042299..1042955 (-)	657	WP_012028219.1	phosphate signaling complex protein PhoU	-
DK876_RS05090 (DK876_05300)	pstB	1042984..1043742 (-)	759	WP_002937614.1	phosphate ABC transporter ATP-binding protein PstB	-
DK876_RS05095 (DK876_05305)	pstB	1043754..1044557 (-)	804	WP_002940866.1	phosphate ABC transporter ATP-binding protein PstB	-

Sequence

Protein

Download Length: 223 a.a. Molecular weight: 25290.00 Da Isoelectric Point: 4.2183

                                >NTDB_id=258273 DK876_RS05070 WP_009909965.1 1039265..1039936(-) (ciaR) [Streptococcus suis strain ISU2714]

MIKILLVEDDLSLSNSVFDFLDDFADVMQVFDGEEGVYEAETGVYDLILLDLMLPEKDGFQVLKELREKGVTTPVLITTA

KESLEDKGHGFELGADDYLTKPFYLEELKMRIQALLKRAGKFNENTLTFGDVTVDLSTNMTMVNGEEVELLGKEFDLLVY

FLQNQNVILPKTQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTTFGENLQTLRSVGYILKNA

Nucleotide

Download Length: 672 bp

                                >NTDB_id=258273 DK876_RS05070 WP_009909965.1 1039265..1039936(-) (ciaR) [Streptococcus suis strain ISU2714]

ATGATTAAAATATTGTTAGTGGAAGATGATTTAAGTCTATCAAATTCTGTTTTCGATTTCTTAGATGATTTTGCGGATGT

TATGCAGGTTTTTGATGGTGAAGAGGGCGTTTATGAGGCGGAAACAGGCGTTTATGATTTGATTCTTTTGGATTTAATGT

TACCTGAAAAAGACGGCTTTCAAGTCTTGAAAGAGTTACGTGAAAAGGGGGTTACGACACCAGTTCTGATTACAACAGCC

AAGGAAAGTCTAGAGGATAAAGGCCATGGTTTTGAATTGGGGGCTGATGACTATTTGACAAAACCGTTTTATTTAGAAGA

ATTGAAGATGCGAATTCAAGCTCTATTAAAACGAGCGGGTAAGTTTAATGAAAACACACTAACCTTTGGAGATGTGACAG

TTGACCTATCTACAAATATGACGATGGTAAATGGCGAAGAAGTTGAACTGTTAGGAAAAGAATTTGATCTACTAGTTTAT

TTCTTGCAAAATCAAAATGTTATTTTGCCAAAAACACAAATTTTTGACCGTATTTGGGGCTTTGACAGTGATACTACAAT

TTCAGTAGTAGAGGTATATGTTTCTAAAATTAGGAAAAAGTTGAAAGGAACGACTTTTGGGGAAAATCTTCAAACCCTGC

GTAGTGTCGGGTACATTCTAAAAAATGCCTAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
ciaR	Streptococcus mutans UA159	90.135	100	0.901
ciaR	Streptococcus pneumoniae Rx1	88.341	100	0.883
ciaR	Streptococcus pneumoniae D39	88.341	100	0.883
ciaR	Streptococcus pneumoniae R6	88.341	100	0.883
ciaR	Streptococcus pneumoniae TIGR4	88.341	100	0.883
covR	Lactococcus lactis subsp. lactis strain DGCC12653	38.496	100	0.39
vicR	Streptococcus mutans UA159	35.47	100	0.372
covR	Streptococcus salivarius strain HSISS4	35.841	100	0.363

Detailed information NTG0258273