Detailed information NTG0258075

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: CWI64_RS04805
• Genome accession: NZ_CP025076
• Coordinates: 907026..908093 (-)
• Length: 355 a.a.
• NCBI ID: WP_000159556.1
• Uniprot ID: A0A0B7LLF7
• Organism: Streptococcus pneumoniae strain BHN97x
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 902026..913093

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CWI64_RS04780 (CWI64_04780)	treR	902197..902907 (+)	711	WP_000760673.1	trehalose operon repressor	Regulator
CWI64_RS04785 (CWI64_04785)	-	902940..903743 (-)	804	WP_000157664.1	ATP-binding cassette domain-containing protein	-
CWI64_RS04790 (CWI64_04790)	-	903756..904649 (-)	894	WP_001012090.1	ABC transporter permease	-
CWI64_RS04795 (CWI64_04795)	-	904661..905598 (-)	938	Protein_909	ABC transporter substrate-binding protein	-
CWI64_RS04800 (CWI64_04800)	amiF	906089..907015 (-)	927	WP_001291293.1	ATP-binding cassette domain-containing protein	Regulator
CWI64_RS04805 (CWI64_04805)	amiE	907026..908093 (-)	1068	WP_000159556.1	ABC transporter ATP-binding protein	Regulator
CWI64_RS04810 (CWI64_04810)	amiD	908102..909028 (-)	927	WP_000103700.1	oligopeptide ABC transporter permease OppC	Regulator
CWI64_RS04815 (CWI64_04815)	amiC	909028..910524 (-)	1497	WP_000759905.1	ABC transporter permease	Regulator
CWI64_RS04820 (CWI64_04820)	amiA3	910591..912570 (-)	1980	WP_000742234.1	peptide ABC transporter substrate-binding protein	Regulator

Sequence

Protein

• Length: 355 a.a.
• Molecular weight: 39504.11 Da
• Isoelectric Point: 4.8764

>NTDB_id=258075 CWI64_RS04805 WP_000159556.1 907026..908093(-) (amiE) [Streptococcus pneumoniae strain BHN97x]
MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALVGESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDL
TALSSHKDWEQIRGAKIATIFQDPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITHDLGVVASIADKVAVMYAGEIVE
YGTVEEVFYDPRHPYTWSLLSSLPQLADDKGELYSIPGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAK
TWLLHEDAPKVEKPAVIANLHDKIREKMGFAHLAD

Nucleotide

• Length: 1068 bp

>NTDB_id=258075 CWI64_RS04805 WP_000159556.1 907026..908093(-) (amiE) [Streptococcus pneumoniae strain BHN97x]
ATGACAAAAGAAAAAAATGTAATTTTGACTGCTCGCGATATTGTCGTGGAATTTGACGTTCGTGACAAAGTATTGACAGC
CATTCGCGGCGTTTCCCTTGAACTAGTCGAAGGAGAAGTATTAGCCTTGGTAGGTGAGTCAGGATCAGGTAAATCTGTTT
TGACAAAGACCTTCACAGGTATGCTCGAAGAAAATGGTCGTATTGCCCAAGGTAGTATTGACTACCGTGGTCAGGACTTG
ACAGCTTTATCTTCTCACAAGGATTGGGAACAAATTCGTGGTGCTAAGATTGCGACTATCTTCCAGGACCCAATGACTAG
TTTGGACCCCATTAAAACAATTGGTAGTCAGATTACAGAAGTTATTGTAAAACACCAAGGAAAAACAGCTAAAGAAGCGA
AAGAATTGGCCATTGACTACATGAATAAGGTTGGCATTCCAGACGCAGATAGACGTTTTAATGAATACCCATTCCAATAT
TCTGGAGGAATGCGTCAACGTATCGTTATTGCGATTGCCCTTGCCTGCCGACCTGATGTCTTGATCTGTGATGAGCCAAC
AACTGCCTTGGATGTAACTATTCAAGCTCAGATTATTGATTTGCTAAAATCTTTACAAAACGAGTATCATTTCACAACAA
TCTTTATTACCCACGACCTTGGTGTGGTGGCAAGTATTGCGGATAAGGTAGCGGTTATGTATGCAGGAGAAATCGTTGAG
TATGGAACGGTTGAGGAAGTCTTCTATGACCCTCGCCATCCATATACATGGAGTCTATTGTCTAGCTTGCCTCAGCTTGC
TGATGATAAAGGGGAACTTTACTCAATCCCAGGAACACCTCCGTCACTTTATACTGACCTGAAAGGGGATGCTTTTGCCT
TGCGTTCTGACTACGCAATGCAGATTGACTTCGAACAAAAAGCTCCTCAATTCTCAGTATCAGAGACACATTGGGCTAAA
ACTTGGCTTCTTCATGAGGATGCTCCGAAAGTAGAAAAACCAGCTGTGATTGCAAATCTCCATGATAAGATCCGTGAAAA
AATGGGATTTGCCCATCTGGCTGACTAG

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (29-187)

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-301)

3D structure

• AlphaFold DB: A0A0B7LLF7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	88.451	100	0.885
amiE	Streptococcus thermophilus LMG 18311	86.479	100	0.865
amiE	Streptococcus thermophilus LMD-9	86.479	100	0.865
oppD	Streptococcus mutans UA159	54.545	99.155	0.541