Detailed information NTG0258075

Bioinformatically predicted

Overview

• Name: ciaR
• Type: Regulator
• Locus tag: DK235_RS05070
• Genome accession: NZ_CP030017
• Coordinates: 1037467..1038138 (-)
• Length: 223 a.a.
• NCBI ID: WP_009909965.1
• Uniprot ID: -
• Organism: Streptococcus suis strain ISU1606
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1032467..1043138

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DK235_RS05050 (DK235_05250)	rpsT	1033267..1033515 (+)	249	WP_012027069.1	30S ribosomal protein S20	-
DK235_RS05055 (DK235_05260)	tnpA	1033657..1034121 (-)	465	WP_012775157.1	IS200/IS605-like element ISSsu4 family transposase	-
DK235_RS05060 (DK235_05270)	-	1034535..1035764 (-)	1230	WP_012027071.1	transglutaminase domain-containing protein	-
DK235_RS05065 (DK235_05280)	ciaH	1036095..1037474 (-)	1380	WP_012027074.1	cell wall metabolism sensor histidine kinase WalK	Regulator
DK235_RS05070 (DK235_05285)	ciaR	1037467..1038138 (-)	672	WP_009909965.1	response regulator transcription factor	Regulator
DK235_RS05075 (DK235_05290)	-	1038332..1038712 (-)	381	WP_012027076.1	hypothetical protein	-
DK235_RS05080 (DK235_05295)	-	1039097..1040299 (+)	1203	WP_012775158.1	IS110 family transposase	-
DK235_RS05085 (DK235_05300)	phoU	1040501..1041157 (-)	657	WP_012028219.1	phosphate signaling complex protein PhoU	-
DK235_RS05090 (DK235_05305)	pstB	1041186..1041944 (-)	759	WP_002937614.1	phosphate ABC transporter ATP-binding protein PstB	-
DK235_RS05095 (DK235_05310)	pstB	1041956..1042759 (-)	804	WP_002940866.1	phosphate ABC transporter ATP-binding protein PstB	-

Sequence

Protein

• Length: 223 a.a.
• Molecular weight: 25290.00 Da
• Isoelectric Point: 4.2183

>NTDB_id=258075 DK235_RS05070 WP_009909965.1 1037467..1038138(-) (ciaR) [Streptococcus suis strain ISU1606]
MIKILLVEDDLSLSNSVFDFLDDFADVMQVFDGEEGVYEAETGVYDLILLDLMLPEKDGFQVLKELREKGVTTPVLITTA
KESLEDKGHGFELGADDYLTKPFYLEELKMRIQALLKRAGKFNENTLTFGDVTVDLSTNMTMVNGEEVELLGKEFDLLVY
FLQNQNVILPKTQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTTFGENLQTLRSVGYILKNA

Nucleotide

• Length: 672 bp

>NTDB_id=258075 DK235_RS05070 WP_009909965.1 1037467..1038138(-) (ciaR) [Streptococcus suis strain ISU1606]
ATGATTAAAATATTGTTAGTGGAAGATGATTTAAGTCTATCAAATTCTGTTTTCGATTTCTTAGATGATTTTGCGGATGT
TATGCAGGTTTTTGATGGTGAAGAGGGCGTTTATGAGGCGGAAACAGGCGTTTATGATTTGATTCTTTTGGATTTAATGT
TACCTGAAAAAGACGGCTTTCAAGTCTTGAAAGAGTTACGTGAAAAGGGGGTTACGACACCAGTTCTGATTACAACAGCC
AAGGAAAGTCTAGAGGATAAAGGCCATGGTTTTGAATTGGGGGCTGATGACTATTTGACAAAACCGTTTTATTTAGAAGA
ATTGAAGATGCGAATTCAAGCTCTATTAAAACGAGCGGGTAAGTTTAATGAAAACACACTAACCTTTGGAGATGTGACAG
TTGACCTATCTACAAATATGACGATGGTAAATGGCGAAGAAGTTGAACTGTTAGGAAAAGAATTTGATCTACTAGTTTAT
TTCTTGCAAAATCAAAATGTTATTTTGCCAAAAACACAAATTTTTGACCGTATTTGGGGCTTTGACAGTGATACTACAAT
TTCAGTAGTAGAGGTATATGTTTCTAAAATTAGGAAAAAGTTGAAAGGAACGACTTTTGGGGAAAATCTTCAAACCCTGC
GTAGTGTCGGGTACATTCTAAAAAATGCCTAA

Domains

Predicted by InterProScan.

• Response regulator receiver domain (Response_reg) (4-112)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (145-220)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaR	Streptococcus mutans UA159	90.135	100	0.901
ciaR	Streptococcus pneumoniae Rx1	88.341	100	0.883
ciaR	Streptococcus pneumoniae D39	88.341	100	0.883
ciaR	Streptococcus pneumoniae R6	88.341	100	0.883
ciaR	Streptococcus pneumoniae TIGR4	88.341	100	0.883
covR	Lactococcus lactis subsp. lactis strain DGCC12653	38.496	100	0.39
vicR	Streptococcus mutans UA159	35.47	100	0.372
covR	Streptococcus salivarius strain HSISS4	35.841	100	0.363