Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   CWI26_RS00380 Genome accession   NZ_CP025043
Coordinates   67167..68066 (+) Length   299 a.a.
NCBI ID   WP_029184821.1    Uniprot ID   A0A2I5KL62
Organism   Streptococcus suis strain AH681     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 62167..73066
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CWI26_RS00355 (CWI26_00355) - 63153..64421 (+) 1269 WP_029184820.1 MerR family transcriptional regulator -
  CWI26_RS00360 (CWI26_00360) tnpA 64745..65209 (+) 465 WP_061746536.1 IS200/IS605-like element ISSsu4 family transposase -
  CWI26_RS00370 (CWI26_00370) ruvB 65371..66372 (+) 1002 WP_024377052.1 Holliday junction branch migration DNA helicase RuvB -
  CWI26_RS00375 (CWI26_00375) - 66440..67063 (+) 624 WP_100881027.1 HAD-IA family hydrolase -
  CWI26_RS00380 (CWI26_00380) comR 67167..68066 (+) 900 WP_029184821.1 helix-turn-helix domain-containing protein Regulator
  CWI26_RS00385 (CWI26_00385) - 68283..69503 (+) 1221 WP_099871686.1 bifunctional folylpolyglutamate synthase/dihydrofolate synthase -
  CWI26_RS00395 (CWI26_00395) - 69694..71217 (+) 1524 WP_024377059.1 quinol oxidase -

Sequence

Protein


Download         Length: 299 a.a.        Molecular weight: 35314.20 Da        Isoelectric Point: 4.3358

>NTDB_id=257582 CWI26_RS00380 WP_029184821.1 67167..68066(+) (comR) [Streptococcus suis strain AH681]
MNDKEFGQRVRQLRETASLTREQFCDDELELSVRQLTRIEAGTSKPTFSKIQYIATRLGMGLYELMPDYVSLPERYSKLK
FDVLRTPTYENEELMGKRADMMTEIYDDYYDDLPEEEKIAIDAIQSIIDVFETKTAEFGQDILEDYFEQIQRKPQFSAND
LLIIRLYLINLRMEIKQSSDFQHFLELVEKLPSQVELIESGELFILRDVMLTSIGILGEHEEYGKIPPLFDALDRIMVST
QDFQKKPILNLLKWKYELYVNNDSEEARRFYEEAVMFAKLIGDSHLVEKLESSWREEEK

Nucleotide


Download         Length: 900 bp        

>NTDB_id=257582 CWI26_RS00380 WP_029184821.1 67167..68066(+) (comR) [Streptococcus suis strain AH681]
ATGAACGATAAGGAATTTGGACAACGTGTACGTCAACTTCGAGAAACCGCTAGTCTGACACGTGAACAGTTTTGCGATGA
CGAACTTGAACTCTCCGTCCGCCAATTAACCCGTATCGAAGCAGGTACTTCTAAGCCGACTTTTTCAAAAATCCAATATA
TCGCAACCCGCTTAGGCATGGGGCTCTACGAGCTTATGCCAGATTATGTGTCGCTACCTGAACGATATTCCAAACTGAAG
TTTGATGTACTTCGTACACCGACTTATGAAAATGAGGAATTGATGGGAAAACGGGCAGATATGATGACAGAAATCTATGA
TGATTATTACGACGACTTGCCTGAGGAGGAGAAAATAGCGATTGATGCCATTCAATCCATTATTGATGTATTTGAAACGA
AGACAGCAGAATTTGGTCAAGATATTCTAGAAGATTATTTTGAACAAATCCAAAGAAAACCCCAATTTTCAGCCAACGAT
TTGTTGATAATTCGACTCTATTTAATCAATTTGAGAATGGAAATTAAACAGAGCAGTGATTTTCAGCACTTTTTAGAGTT
GGTGGAAAAGTTACCAAGCCAAGTAGAATTGATTGAATCTGGAGAATTATTTATTTTAAGAGATGTGATGCTGACGTCGA
TAGGGATTCTTGGTGAACATGAAGAATATGGCAAGATACCTCCACTTTTTGATGCTCTAGATAGAATCATGGTTTCAACT
CAAGATTTTCAAAAGAAACCCATTCTCAATCTGCTTAAGTGGAAATATGAGTTGTATGTGAACAATGATAGCGAGGAGGC
TAGACGGTTTTATGAAGAAGCAGTTATGTTCGCAAAATTAATTGGAGACTCCCATTTAGTAGAAAAGCTAGAATCATCAT
GGAGAGAAGAGGAAAAGTGA

Domains

Predicted by InterproScan.

ComR tetratricopeptide (ComR_TPR)

(73-294)

Helix-turn-helix domain (HTH_31)

(5-60)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2I5KL62

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus suis P1/7

68.136

98.662

0.672
  comR Streptococcus suis 05ZYH33

68.136

98.662

0.672
  comR Streptococcus suis D9

61.538

100

0.615
  comR Streptococcus mutans UA159

42.14

100

0.421
  comR Streptococcus pyogenes MGAS8232

37.71

99.331

0.375
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

38.542

96.321

0.371
  comR Streptococcus pyogenes MGAS315

36.486

98.997

0.361

Multiple sequence alignment