Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   CVO91_RS12905 Genome accession   NZ_CP024974
Coordinates   2536671..2537867 (+) Length   398 a.a.
NCBI ID   WP_004195348.1    Uniprot ID   A0A2I5KIT8
Organism   Streptococcus suis strain CZ130302     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2531671..2542867
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CVO91_RS12855 (CVO91_12855) - 2532400..2532585 (+) 186 WP_002942274.1 hypothetical protein -
  CVO91_RS12860 (CVO91_12860) tnpB 2532566..2532916 (+) 351 WP_002941575.1 IS66 family insertion sequence element accessory protein TnpB -
  CVO91_RS12865 (CVO91_12865) - 2532968..2533174 (+) 207 WP_002941576.1 hypothetical protein -
  CVO91_RS12870 (CVO91_12870) - 2533128..2534480 (+) 1353 WP_004195537.1 IS66-like element short variant transposase -
  CVO91_RS12875 (CVO91_12875) - 2534681..2534836 (-) 156 WP_241033702.1 hypothetical protein -
  CVO91_RS12895 (CVO91_12895) - 2535310..2535993 (-) 684 WP_002941740.1 YoaK family protein -
  CVO91_RS12900 (CVO91_12900) rlmH 2536018..2536497 (-) 480 WP_002941741.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  CVO91_RS12905 (CVO91_12905) htrA 2536671..2537867 (+) 1197 WP_004195348.1 trypsin-like peptidase domain-containing protein Regulator
  CVO91_RS12910 (CVO91_12910) spo0J 2537928..2538692 (+) 765 WP_004195351.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 398 a.a.        Molecular weight: 41758.83 Da        Isoelectric Point: 4.5454

>NTDB_id=256951 CVO91_RS12905 WP_004195348.1 2536671..2537867(+) (htrA) [Streptococcus suis strain CZ130302]
MERIPYMKKYLKFAILFVIGFLGGLIGALSASFFQPQIQQANSAITSVSNVQYNNETSTTKAVEKVQNAVVSVINYQKSA
NNSLGAIFGNIESSDELAVAGEGSGVIYKKDGQYAYVVTNTHVINNAEKIDILLASGEKISGELVGSDTYSDIAVIKISA
DKVTAVAEFADSDTIKVGETAIAIGSPLGSVYANTVTQGIISSLSRTVTSQSEDGQTISTNAIQTDTAINPGNSGGPLIN
IQGQVIGITSSKITSSSVSSSGVAVEGMGFAIPANDAVAIINQLEKAGKVSRPALGVHMVNLTTLSTSQLEKAGLSNTEL
TSGVVIVSTQSGLPADGKLETFDVITEIDGEAIQNKSDLQSALYKHQIGDTITVTYYRNNQKQTVDIKLTHSTEELSE

Nucleotide


Download         Length: 1197 bp        

>NTDB_id=256951 CVO91_RS12905 WP_004195348.1 2536671..2537867(+) (htrA) [Streptococcus suis strain CZ130302]
ATGGAAAGGATTCCTTATATGAAAAAATATTTGAAATTTGCGATTTTATTTGTAATTGGATTTTTGGGTGGTCTTATCGG
GGCCTTATCAGCCTCTTTCTTCCAACCACAGATTCAACAAGCAAATTCTGCTATCACTAGTGTCAGCAATGTTCAATATA
ATAATGAAACTTCCACCACAAAAGCTGTAGAGAAAGTACAAAATGCTGTTGTGTCTGTTATTAATTACCAAAAGTCAGCC
AACAATAGTCTTGGTGCTATCTTTGGAAATATTGAATCATCTGACGAACTAGCTGTTGCTGGAGAGGGGTCTGGGGTTAT
CTATAAAAAAGATGGTCAATATGCCTATGTTGTGACAAATACGCATGTTATTAATAACGCAGAAAAGATTGATATTCTTT
TAGCATCTGGAGAAAAAATCAGCGGTGAACTCGTTGGTTCCGATACCTATTCTGATATAGCTGTTATAAAAATATCAGCA
GATAAAGTCACTGCTGTTGCTGAATTTGCTGATTCCGATACAATTAAAGTTGGAGAAACTGCTATCGCAATTGGTAGTCC
TCTAGGTAGCGTCTACGCCAATACAGTTACTCAAGGTATTATTTCTAGCCTAAGTCGGACAGTTACTTCACAATCAGAAG
ATGGTCAAACAATCTCAACCAACGCTATTCAAACCGATACAGCTATCAACCCTGGAAACTCTGGAGGACCATTGATTAAT
ATCCAAGGACAAGTTATTGGTATCACCTCTAGCAAAATCACCTCAAGTTCTGTAAGTAGCTCAGGTGTGGCTGTGGAAGG
GATGGGATTCGCTATTCCTGCAAATGATGCCGTAGCCATTATCAATCAACTTGAGAAAGCTGGAAAAGTTAGCCGACCTG
CTCTTGGAGTTCATATGGTTAACTTGACGACCTTGTCAACTAGTCAATTAGAAAAGGCTGGATTATCAAATACAGAATTA
ACATCCGGTGTCGTAATTGTCTCTACACAAAGTGGACTACCTGCAGATGGAAAATTAGAAACTTTTGATGTTATTACTGA
GATTGACGGAGAAGCTATTCAAAATAAGAGTGACCTCCAGAGCGCTCTCTACAAACATCAAATTGGAGATACAATCACTG
TAACTTATTACCGCAATAATCAGAAACAAACTGTTGACATTAAGTTGACACATTCTACAGAAGAACTTAGCGAATAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(293-389)

Trypsin-like peptidase domain (Trypsin_2)

(103-248)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2I5KIT8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

60.453

99.749

0.603
  htrA Streptococcus gordonii str. Challis substr. CH1

60.506

99.246

0.6
  htrA Streptococcus pneumoniae Rx1

56.997

98.744

0.563
  htrA Streptococcus pneumoniae D39

56.997

98.744

0.563
  htrA Streptococcus pneumoniae R6

56.997

98.744

0.563
  htrA Streptococcus pneumoniae TIGR4

56.997

98.744

0.563
  htrA Streptococcus mitis NCTC 12261

56.997

98.744

0.563

Multiple sequence alignment