Detailed information NTG0256901

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: CVO91_RS00425
• Genome accession: NZ_CP024974
• Coordinates: 69168..70067 (+)
• Length: 299 a.a.
• NCBI ID: WP_004195451.1
• Uniprot ID: A0AA87K4R4
• Organism: Streptococcus suis strain CZ130302
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 64168..75067

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CVO91_RS00385 (CVO91_00385)	tnpA	64525..64989 (+)	465	WP_002939996.1	IS200/IS605-like element ISSsu4 family transposase	-
CVO91_RS00400 (CVO91_00400)	lacA	65299..65721 (+)	423	WP_002941127.1	galactose-6-phosphate isomerase subunit LacA	-
CVO91_RS00405 (CVO91_00405)	-	65956..66138 (+)	183	WP_033875507.1	MerR family transcriptional regulator	-
CVO91_RS00410 (CVO91_00410)	-	66177..67226 (+)	1050	WP_050810541.1	hypothetical protein	-
CVO91_RS00415 (CVO91_00415)	ruvB	67371..68372 (+)	1002	WP_004195448.1	Holliday junction branch migration DNA helicase RuvB	-
CVO91_RS00420 (CVO91_00420)	-	68440..69063 (+)	624	WP_004195449.1	HAD-IA family hydrolase	-
CVO91_RS00425 (CVO91_00425)	comR	69168..70067 (+)	900	WP_004195451.1	helix-turn-helix domain-containing protein	Regulator
CVO91_RS00430 (CVO91_00430)	-	70284..71504 (+)	1221	WP_004195453.1	folylpolyglutamate synthase/dihydrofolate synthase family protein	-
CVO91_RS00440 (CVO91_00440)	-	71695..73218 (+)	1524	WP_004195456.1	hypothetical protein	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35314.19 Da
• Isoelectric Point: 4.3390

>NTDB_id=256901 CVO91_RS00425 WP_004195451.1 69168..70067(+) (comR) [Streptococcus suis strain CZ130302]
MNDKEFGQRVRQLRETASLTREQFCGDELELSVRQLTRIEAGTSKPTFSKIQYIATRLGMGLYELMPDYVSLPERYSKLK
FDVLRTPTYENEELMEKRADMMTEIYDDYYDDLPEEEKIAIDAIQSIIDVFETKTAEFGQDILEDYFEQIQRKTQFSAND
LLIIRLYLINLRIEIKQSSDFQHFLELVEKLPSQVELIESGELFILRDVMLTSIGILGEHEEYGKIPPLFDALDRIMVST
QDFQKKPILNLLKWKYELYVNNDSEEARRFYEEAVMFAKLIGDSHLVEKLESSWREEEK

Nucleotide

• Length: 900 bp

>NTDB_id=256901 CVO91_RS00425 WP_004195451.1 69168..70067(+) (comR) [Streptococcus suis strain CZ130302]
ATGAACGATAAGGAATTTGGACAACGTGTACGTCAACTTCGAGAAACCGCTAGTCTGACACGTGAACAGTTTTGCGGTGA
CGAACTTGAGCTCTCCGTCCGCCAATTAACCCGTATCGAAGCAGGTACTTCTAAGCCAACTTTTTCAAAAATCCAATATA
TCGCAACCCGCTTAGGCATGGGGCTCTATGAGCTTATGCCAGATTATGTGTCGCTACCTGAACGATATTCCAAACTGAAG
TTTGATGTCCTCCGTACACCGACTTATGAAAATGAGGAATTGATGGAAAAACGGGCAGATATGATGACAGAAATCTATGA
TGACTATTATGATGACTTGCCTGAAGAAGAGAAAATAGCGATTGATGCCATTCAATCCATTATTGATGTATTTGAAACGA
AGACAGCAGAATTTGGTCAAGATATTCTAGAAGATTATTTTGAACAAATCCAAAGAAAAACCCAATTTTCAGCCAACGAT
TTGTTGATAATTCGACTCTATTTAATCAATTTGAGAATAGAAATTAAACAGAGCAGTGATTTTCAGCACTTTTTAGAGTT
GGTGGAAAAGTTACCCAGCCAAGTAGAATTGATTGAATCTGGAGAATTATTTATTTTAAGAGATGTGATGCTGACGTCGA
TAGGGATTCTTGGCGAACATGAAGAATATGGCAAGATACCTCCACTTTTTGATGCTCTAGATAGAATCATGGTTTCAACT
CAAGATTTTCAAAAGAAACCCATTCTCAATCTGCTTAAGTGGAAATATGAGTTGTATGTGAACAATGATAGCGAGGAGGC
TAGACGGTTTTATGAAGAAGCAGTTATGTTCGCAAAATTAATTGGAGACTCCCATTTAGTAGAAAAATTAGAATCATCAT
GGAGAGAAGAGGAAAAGTGA

Domains

Predicted by InterproScan.

• ComR tetratricopeptide (ComR_TPR) (73-294)

• Helix-turn-helix domain (HTH_31) (5-60)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus suis P1/7	68.136	98.662	0.672
comR	Streptococcus suis 05ZYH33	68.136	98.662	0.672
comR	Streptococcus suis D9	61.538	100	0.615
comR	Streptococcus mutans UA159	42.475	100	0.425
comR	Streptococcus pyogenes MGAS8232	38.384	99.331	0.381
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	38.889	96.321	0.375
comR	Streptococcus pyogenes MGAS315	36.824	98.997	0.365