Detailed information NTG0255805

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: CTW00_RS02685
• Genome accession: NZ_CP024843
• Coordinates: 575916..577118 (+)
• Length: 400 a.a.
• NCBI ID: WP_003100537.1
• Uniprot ID: A0A1S1XXM8
• Organism: Streptococcus iniae strain FP5228
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 570916..582118

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CTW00_RS02660 (CTW00_00539)	-	571910..574504 (+)	2595	WP_003100534.1	YfhO family protein	-
CTW00_RS10355	-	574831..574947 (-)	117	Protein_520	IS30 family transposase	-
CTW00_RS02680 (CTW00_00543)	rlmH	575291..575770 (-)	480	WP_003100536.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
CTW00_RS02685 (CTW00_00544)	htrA	575916..577118 (+)	1203	WP_003100537.1	S1C family serine protease	Regulator
CTW00_RS02690 (CTW00_00545)	spo0J	577197..577970 (+)	774	WP_016356271.1	ParB/RepB/Spo0J family partition protein	Regulator
CTW00_RS02695 (CTW00_00546)	dnaA	578205..579560 (+)	1356	WP_003100539.1	chromosomal replication initiator protein DnaA	-
CTW00_RS02700 (CTW00_00547)	dnaN	579716..580852 (+)	1137	WP_003100540.1	DNA polymerase III subunit beta	-
CTW00_RS02705 (CTW00_00548)	-	580914..581111 (+)	198	WP_003100542.1	DUF951 family protein	-

Sequence

Protein

• Length: 400 a.a.
• Molecular weight: 42463.20 Da
• Isoelectric Point: 6.7483

>NTDB_id=255805 CTW00_RS02685 WP_003100537.1 575916..577118(+) (htrA) [Streptococcus iniae strain FP5228]
MSHFKNIYKLIWVLLAGFLGGFFAFIVINTFNQKTSTQETIISNPTKTSKVTYKNTTNTTKAVKVIQNAVVSVLNYQAVD
TNTSNPASQLFGQENDLKKDDGLALFSEGSGVIYKKDDKSAYLVTNNHVIDGAKRIEILLADGSKVVGKLVGSDTYSDLA
VVKISADKIKSIGEFADSTKINVGEVAIAIGSPLGSEYANSVTEGIVSSLSRTVTLKNEEGQTVSTNALQTDAAINPGNS
GGPLINIEGQIIGINSSKISSGSNGGAVEGMGFAIPSNDVLKIINQLEGKGEVIRPALGISMVNLGDLSTNAISQLKIPK
DLTGGIVVASVKEGMPASGKLEQYDIITEINGKAVTTTSDLQSELYGHNIDDSIKITFYRGKDKKTDTIKLTKTTKDLEK

Nucleotide

• Length: 1203 bp

>NTDB_id=255805 CTW00_RS02685 WP_003100537.1 575916..577118(+) (htrA) [Streptococcus iniae strain FP5228]
ATGTCACATTTTAAAAATATATACAAATTAATTTGGGTTCTTTTGGCAGGCTTTTTAGGTGGTTTTTTTGCATTTATAGT
TATTAATACCTTTAATCAAAAAACTTCTACACAAGAGACAATTATTTCAAATCCTACTAAAACAAGTAAAGTAACTTATA
AAAACACAACTAATACAACTAAAGCGGTAAAGGTTATCCAAAATGCTGTTGTATCTGTGCTCAATTATCAAGCAGTTGAT
ACAAATACGTCAAATCCTGCAAGTCAACTTTTTGGACAAGAAAATGATTTAAAAAAAGATGACGGGCTAGCTCTTTTTAG
TGAAGGATCTGGTGTCATTTATAAAAAAGATGATAAATCTGCTTATTTAGTAACAAATAATCATGTTATTGATGGTGCTA
AACGAATTGAAATTCTACTAGCTGATGGTTCTAAAGTTGTTGGAAAATTAGTTGGTTCTGATACTTATTCAGATTTAGCT
GTTGTTAAAATTTCAGCTGATAAAATTAAATCTATTGGAGAATTTGCTGACTCTACAAAAATAAATGTTGGTGAAGTTGC
AATTGCTATTGGTAGCCCACTGGGATCTGAATATGCTAATTCCGTAACAGAAGGTATTGTTTCAAGTCTTAGCAGAACAG
TTACTCTAAAAAATGAAGAAGGACAGACCGTTTCAACAAATGCTCTACAAACAGATGCAGCAATTAATCCTGGTAATTCA
GGTGGTCCATTAATCAATATTGAAGGGCAAATTATTGGGATTAATTCAAGTAAAATTTCTTCAGGTTCAAATGGAGGAGC
TGTCGAAGGAATGGGATTTGCAATTCCTTCCAATGACGTTCTTAAAATTATTAATCAACTTGAAGGAAAAGGAGAAGTGA
TTCGTCCTGCCTTAGGCATTTCAATGGTTAATCTTGGTGATCTGTCAACAAATGCAATTAGCCAATTAAAGATTCCAAAG
GACTTAACAGGTGGTATTGTTGTCGCATCTGTCAAAGAAGGGATGCCTGCTTCAGGAAAACTTGAGCAATACGATATTAT
TACAGAAATTAATGGCAAAGCTGTCACTACAACAAGTGATCTTCAAAGTGAATTATATGGACATAATATTGACGACTCAA
TCAAAATAACTTTCTATAGAGGAAAAGATAAGAAAACAGATACCATCAAACTAACAAAGACAACTAAAGATTTAGAAAAA
TAA

Domains

Predicted by InterproScan.

• Peptidase family M50 (Peptidase_M50) (11-396)

• Trypsin-like peptidase domain (Trypsin_2) (109-254)

• PDZ domain (PDZ_2) (296-391)

3D structure

• AlphaFold DB: A0A1S1XXM8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	62.025	98.75	0.612
htrA	Streptococcus mitis NCTC 12261	54.208	100	0.548
htrA	Streptococcus gordonii str. Challis substr. CH1	54.637	99.75	0.545
htrA	Streptococcus pneumoniae TIGR4	53.96	100	0.545
htrA	Streptococcus pneumoniae D39	53.96	100	0.545
htrA	Streptococcus pneumoniae Rx1	53.96	100	0.545
htrA	Streptococcus pneumoniae R6	53.96	100	0.545