Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   DMB38_RS16500 Genome accession   NZ_CP029618
Coordinates   3823274..3823972 (-) Length   232 a.a.
NCBI ID   WP_125935836.1    Uniprot ID   -
Organism   Streptomyces sp. WAC 06738     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3818274..3828972
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DMB38_RS16490 (DMB38_16480) - 3819741..3821318 (+) 1578 WP_125935834.1 aminopeptidase P family protein -
  DMB38_RS16495 (DMB38_16485) - 3821557..3823281 (-) 1725 WP_125935835.1 HAMP domain-containing sensor histidine kinase -
  DMB38_RS16500 (DMB38_16490) ciaR 3823274..3823972 (-) 699 WP_125935836.1 response regulator transcription factor Regulator
  DMB38_RS16505 (DMB38_16495) - 3824103..3824639 (+) 537 WP_125935837.1 PepSY domain-containing protein -
  DMB38_RS16510 (DMB38_16500) - 3824842..3825357 (-) 516 WP_125935838.1 DUF1772 domain-containing protein -
  DMB38_RS16515 (DMB38_16505) - 3825350..3826180 (-) 831 WP_125935839.1 NAD(P)H-binding protein -
  DMB38_RS16520 (DMB38_16510) - 3826262..3827203 (+) 942 WP_125935840.1 AraC family transcriptional regulator -
  DMB38_RS16525 (DMB38_16515) - 3827358..3828461 (+) 1104 WP_125935841.1 ionic transporter y4hA -

Sequence

Protein


Download         Length: 232 a.a.        Molecular weight: 24995.42 Da        Isoelectric Point: 4.8891

>NTDB_id=255125 DMB38_RS16500 WP_125935836.1 3823274..3823972(-) (ciaR) [Streptomyces sp. WAC 06738]
MRLLIVEDERRLATSLARGLAAEGFAVDVVHDGVEGLHRATETDYDLIVLDIMLPGLNGYRVCAALRAAGDETPILMLTA
KDGEYDEAEGLDTGADDYLTKPFSYVVLLARVRALLRRRGRTAAPVLRVGALAVDPAARRVHVGDTEVTLTTKEFAVLEV
LAQRAGEVVAKSEILDHAWDFAYDGDPNIVEVYVSALRRKLGARTIQTVRGAGYRLADPGPDPDTAGGSARA

Nucleotide


Download         Length: 699 bp        

>NTDB_id=255125 DMB38_RS16500 WP_125935836.1 3823274..3823972(-) (ciaR) [Streptomyces sp. WAC 06738]
ATGCGACTGCTGATCGTCGAGGACGAGCGACGTCTCGCCACCTCCCTCGCCCGCGGGCTCGCCGCCGAGGGCTTCGCCGT
GGACGTCGTCCACGACGGCGTCGAGGGCCTGCACCGGGCCACCGAGACCGACTACGACCTCATCGTCCTCGACATCATGC
TCCCCGGCCTGAACGGCTACCGCGTCTGCGCCGCCCTCCGCGCCGCCGGCGACGAGACCCCCATCCTCATGCTCACCGCC
AAGGACGGCGAGTACGACGAGGCCGAGGGCCTCGACACCGGCGCCGACGACTACCTCACCAAGCCCTTCAGCTACGTCGT
CCTCCTCGCCCGCGTACGCGCCCTCCTGCGCCGCCGCGGCCGCACCGCCGCCCCCGTCCTGCGCGTCGGCGCCCTCGCCG
TCGACCCCGCCGCGCGCCGGGTCCACGTCGGCGACACCGAGGTGACGCTGACGACCAAGGAGTTCGCGGTCCTCGAAGTG
CTCGCGCAGCGCGCCGGCGAGGTCGTCGCCAAGTCCGAGATCCTCGACCACGCCTGGGACTTCGCCTACGACGGCGACCC
CAACATCGTCGAGGTCTACGTCAGCGCCCTGCGCCGCAAACTCGGCGCCCGCACCATCCAGACCGTACGCGGCGCCGGCT
ACCGGCTCGCCGACCCCGGCCCCGACCCCGACACCGCCGGCGGCAGCGCCCGTGCGTAG

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(146-216)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus mutans UA159

43.498

96.121

0.418
  ciaR Streptococcus pneumoniae Rx1

42.152

96.121

0.405
  ciaR Streptococcus pneumoniae D39

42.152

96.121

0.405
  ciaR Streptococcus pneumoniae R6

42.152

96.121

0.405
  ciaR Streptococcus pneumoniae TIGR4

42.152

96.121

0.405
  covR Lactococcus lactis subsp. lactis strain DGCC12653

42.081

95.259

0.401
  covR Streptococcus salivarius strain HSISS4

41.441

95.69

0.397
  vicR Streptococcus mutans UA159

39.13

99.138

0.388