Detailed information NTG0249081

Bioinformatically predicted

Overview

• Name: comGF
• Type: Machinery gene
• Locus tag: C1A39_RS08795
• Genome accession: NZ_CP028896
• Coordinates: 1701877..1702314 (-)
• Length: 145 a.a.
• NCBI ID: WP_011681686.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain CS5
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1696877..1707314

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C1A39_RS08760 (C1A39_09005)	-	1696940..1697602 (-)	663	WP_011681679.1	type II CAAX endopeptidase family protein	-
C1A39_RS08765 (C1A39_09010)	-	1697699..1698142 (-)	444	WP_011681680.1	hypothetical protein	-
C1A39_RS10125 (C1A39_09015)	-	1698216..1698554 (-)	339	WP_224103197.1	CPBP family intramembrane glutamic endopeptidase	-
C1A39_RS10130 (C1A39_09020)	-	1698598..1698873 (-)	276	WP_011681681.1	hypothetical protein	-
C1A39_RS08775 (C1A39_09025)	-	1698885..1699083 (-)	199	Protein_1680	helix-turn-helix transcriptional regulator	-
C1A39_RS08780 (C1A39_09030)	-	1699332..1700525 (-)	1194	WP_014608740.1	acetate kinase	-
C1A39_RS08785 (C1A39_09035)	comGH	1700581..1701537 (-)	957	WP_011681684.1	class I SAM-dependent methyltransferase	Machinery gene
C1A39_RS08790 (C1A39_09040)	comGG	1701582..1701899 (-)	318	WP_011681685.1	competence type IV pilus minor pilin ComGG	Machinery gene
C1A39_RS08795 (C1A39_09045)	comGF	1701877..1702314 (-)	438	WP_011681686.1	competence type IV pilus minor pilin ComGF	Machinery gene
C1A39_RS08800 (C1A39_09050)	comGE	1702298..1702591 (-)	294	WP_024704238.1	competence type IV pilus minor pilin ComGE	Machinery gene
C1A39_RS08805 (C1A39_09055)	comGD	1702563..1702991 (-)	429	WP_011226626.1	competence type IV pilus minor pilin ComGD	Machinery gene
C1A39_RS08810 (C1A39_09060)	comGC	1702951..1703277 (-)	327	WP_002946126.1	competence type IV pilus major pilin ComGC	Machinery gene
C1A39_RS08815 (C1A39_09065)	comGB	1703274..1704374 (-)	1101	WP_120764773.1	competence type IV pilus assembly protein ComGB	Machinery gene
C1A39_RS08820 (C1A39_09070)	comGA/cglA/cilD	1704256..1705197 (-)	942	WP_022096896.1	competence type IV pilus ATPase ComGA	Machinery gene
C1A39_RS08825 (C1A39_09075)	-	1705278..1705640 (-)	363	WP_014622006.1	DUF1033 family protein	-

Sequence

Protein

• Length: 145 a.a.
• Molecular weight: 16375.85 Da
• Isoelectric Point: 8.4500

>NTDB_id=249081 C1A39_RS08795 WP_011681686.1 1701877..1702314(-) (comGF) [Streptococcus thermophilus strain CS5]
MYLSSKLRAFTLLECLVALLVIAGSVQVYQGLTTVLVSNVKQVRQQENQDWLLFVQQMEAELEGCQLVKVEGNKLYVKQD
NQDLAFGLSSASDFRKTNADGRGYQPMLFDVKSSKVSQKNQIVTIQVTLKNELQRSFVYAFEKTG

Nucleotide

• Length: 438 bp

>NTDB_id=249081 C1A39_RS08795 WP_011681686.1 1701877..1702314(-) (comGF) [Streptococcus thermophilus strain CS5]
ATGTATCTAAGCAGTAAGCTGCGTGCCTTTACCCTCTTGGAATGTCTAGTGGCCTTGTTGGTCATTGCTGGCTCAGTTCA
AGTTTATCAAGGGTTAACCACTGTACTTGTGAGTAATGTTAAGCAGGTAAGACAACAAGAAAACCAAGATTGGCTTCTAT
TTGTTCAACAAATGGAGGCAGAATTAGAAGGATGTCAGTTGGTCAAGGTAGAGGGGAACAAACTCTATGTCAAGCAGGAT
AATCAAGACTTGGCTTTTGGTCTTTCAAGTGCCTCTGATTTTCGAAAAACAAATGCTGATGGTCGAGGTTATCAACCAAT
GCTTTTCGATGTCAAATCTAGTAAGGTAAGTCAAAAGAACCAGATAGTTACCATCCAAGTGACTCTTAAAAATGAACTAC
AAAGGAGTTTTGTTTATGCTTTTGAAAAAACAGGTTAG

Domains

Predicted by InterProScan.

• Putative Competence protein ComGF (ComGF) (39-134)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF	Streptococcus mutans UA140	58.156	97.241	0.566
comGF	Streptococcus mutans UA159	57.447	97.241	0.559
comGF/cglF	Streptococcus pneumoniae D39	49.286	96.552	0.476
comGF/cglF	Streptococcus pneumoniae Rx1	49.286	96.552	0.476
comGF/cglF	Streptococcus pneumoniae R6	49.286	96.552	0.476
comGF/cglF	Streptococcus pneumoniae TIGR4	49.286	96.552	0.476
comGF/cglF	Streptococcus mitis NCTC 12261	47.518	97.241	0.462
comGF/cglF	Streptococcus mitis SK321	46.809	97.241	0.455
comGF	Lactococcus lactis subsp. cremoris KW2	45.324	95.862	0.434