Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   SAK_RS00400 Genome accession   NC_007432
Coordinates   63833..64741 (+) Length   302 a.a.
NCBI ID   WP_000912095.1    Uniprot ID   -
Organism   Streptococcus agalactiae A909     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 58833..69741
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SAK_RS00380 (SAK_0077) purE 59350..59838 (+) 489 WP_001182531.1 5-(carboxyamino)imidazole ribonucleotide mutase -
  SAK_RS00385 (SAK_0078) purK 59825..60916 (+) 1092 WP_001084008.1 5-(carboxyamino)imidazole ribonucleotide synthase -
  SAK_RS00390 (SAK_0079) - 60969..62360 (+) 1392 WP_001079797.1 hypothetical protein -
  SAK_RS00395 (SAK_0080) purB 62382..63680 (+) 1299 WP_000572890.1 adenylosuccinate lyase -
  SAK_RS00400 (SAK_0081) comR 63833..64741 (+) 909 WP_000912095.1 helix-turn-helix domain-containing protein Regulator
  SAK_RS00405 (SAK_0082) ruvB 64942..65940 (+) 999 WP_000196633.1 Holliday junction branch migration DNA helicase RuvB Machinery gene
  SAK_RS00410 (SAK_0083) - 66092..66529 (+) 438 WP_000754818.1 low molecular weight protein-tyrosine-phosphatase -
  SAK_RS00415 (SAK_0084) - 66536..66916 (+) 381 WP_000787702.1 membrane protein -
  SAK_RS00420 (SAK_0085) - 66913..68691 (+) 1779 WP_001220907.1 acyltransferase family protein -

Sequence

Protein


Download         Length: 302 a.a.        Molecular weight: 35727.11 Da        Isoelectric Point: 5.5329

>NTDB_id=24847 SAK_RS00400 WP_000912095.1 63833..64741(+) (comR) [Streptococcus agalactiae A909]
MLKHFGSKVRKFRESQQVTREEFCGDESELSVRQLARIEAGESVPNLSKAHYIARNLGVSLDSLTAGASLELSKKYKELK
YLILRTPTYNDTDRLDLIEKYLDEIYLNFYDDLPEDEKIAIESIQSSLDIYISKSHHFGDDLIREYMNQIKRKKIYSIND
LLIIKLWQYKITASRYDPNIFKIDTFIGTIDKLLNQVKVLSIENLFLLRDVLIYSLGILFILAEYQQIENIINTLNDILI
KTQDFQKRPIIDMFEWKYQLFYKENREVAKRKYQESTLFAQLIGDQVLVTQLKEEWKADYIE

Nucleotide


Download         Length: 909 bp        

>NTDB_id=24847 SAK_RS00400 WP_000912095.1 63833..64741(+) (comR) [Streptococcus agalactiae A909]
ATGTTAAAACATTTTGGTAGTAAAGTAAGGAAGTTTAGGGAATCTCAACAGGTGACACGAGAAGAATTTTGTGGCGATGA
ATCAGAGTTATCGGTCCGACAGCTGGCTCGGATTGAAGCAGGAGAATCTGTTCCAAATTTATCTAAGGCGCATTATATCG
CTAGAAATCTAGGAGTTAGTTTAGATTCCTTAACAGCAGGAGCGAGTTTAGAACTGTCAAAAAAATATAAGGAATTAAAG
TATCTTATATTAAGGACGCCTACCTACAATGATACAGATAGACTTGATTTGATTGAAAAATATCTAGATGAGATTTATTT
AAATTTCTATGATGATTTACCTGAAGATGAAAAAATAGCAATTGAGTCCATACAAAGTTCTTTAGATATTTATATTTCTA
AAAGCCATCATTTTGGAGATGACCTGATTAGGGAATACATGAATCAAATTAAACGAAAAAAGATTTACTCTATCAATGAC
TTACTTATAATTAAACTATGGCAATATAAGATTACTGCTAGCAGGTATGATCCCAATATTTTTAAAATAGATACATTTAT
TGGTACTATAGATAAGTTGCTTAATCAAGTAAAGGTATTATCAATTGAAAACCTGTTTTTATTAAGGGATGTCCTCATTT
ATTCGTTAGGTATATTGTTTATATTAGCTGAATATCAGCAAATAGAAAATATAATAAATACTCTAAATGATATTTTAATA
AAAACTCAGGATTTTCAAAAGAGGCCAATAATAGATATGTTCGAATGGAAATATCAGTTGTTTTATAAAGAAAATAGGGA
AGTGGCTAAAAGAAAGTATCAGGAATCAACTCTTTTTGCTCAATTAATTGGCGATCAAGTTTTAGTTACACAGCTAAAAG
AGGAATGGAAAGCAGACTATATAGAATAA

Domains

Predicted by InterProScan.

ComR tetratricopeptide (ComR_TPR)

(74-296)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus mutans UA159

45.151

99.007

0.447
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

45.296

95.033

0.43
  comR Streptococcus pyogenes MGAS315

43.478

99.007

0.43
  comR Streptococcus pyogenes MGAS8232

41.914

100

0.421
  comR Streptococcus suis P1/7

42.424

98.344

0.417
  comR Streptococcus suis 05ZYH33

42.424

98.344

0.417
  comR Streptococcus suis D9

38.384

98.344

0.377

Multiple sequence alignment