Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   CO686_RS09355 Genome accession   NZ_CP023507
Coordinates   1901798..1903147 (+) Length   449 a.a.
NCBI ID   WP_096753745.1    Uniprot ID   -
Organism   Streptococcus oralis strain FDAARGOS_367     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1896798..1908147
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CO686_RS09320 (CO686_09320) - 1897201..1897437 (+) 237 WP_000136436.1 acyl carrier protein -
  CO686_RS09325 (CO686_09325) - 1897882..1898025 (+) 144 WP_049549867.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  CO686_RS09330 (CO686_09330) - 1898040..1898189 (+) 150 WP_033629144.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  CO686_RS10360 - 1898202..1898378 (+) 177 WP_000793177.1 hypothetical protein -
  CO686_RS10365 - 1898528..1898683 (+) 156 WP_000661692.1 hypothetical protein -
  CO686_RS10510 (CO686_09335) - 1898708..1898920 (+) 213 WP_049549866.1 hypothetical protein -
  CO686_RS09340 (CO686_09340) - 1899000..1899188 (+) 189 WP_000722238.1 hypothetical protein -
  CO686_RS09345 (CO686_09345) - 1899213..1899422 (+) 210 WP_000869801.1 hypothetical protein -
  CO686_RS09350 (CO686_09350) comA 1899632..1901785 (+) 2154 WP_070800199.1 peptide cleavage/export ABC transporter ComA Regulator
  CO686_RS09355 (CO686_09355) comB 1901798..1903147 (+) 1350 WP_096753745.1 competence pheromone export protein ComB Regulator
  CO686_RS09360 (CO686_09360) purC 1903316..1904023 (+) 708 WP_007522563.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
  CO686_RS09365 (CO686_09365) - 1904079..1907804 (+) 3726 WP_096753747.1 phosphoribosylformylglycinamidine synthase -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 49952.95 Da        Isoelectric Point: 5.5801

>NTDB_id=247896 CO686_RS09355 WP_096753745.1 1901798..1903147(+) (comB) [Streptococcus oralis strain FDAARGOS_367]
MKPEFLESAEFYNRRYHNFSSRVILPMSLLLVFLLGFAVFAEKEMSLSTRATVEPSRIIANIQSTSNQRIVGNYLEENKL
VKQGDLLVQYQQGAEAVQVEAYASQLEMLKDQKKQLGYLQSSLKEGSDQFPEADKFGYQEMFRDYLSQVSSLRSNVSQQN
ASISSQNAAASQSQAEIGNLISQTEDKIRDYKTAKSAIEKGDQLDSQNPAYSFYQTYKNQGEEDPQAKSQVIAQVDAQIA
QLESSLATYRVQYAGSGAQQAHATGLDSQLESLKSQHLVKVGQELTLLDQKILEAESGKKVQGGLLDKGKITASEDGVLH
LNPETSDSTMAAEGTLLAQLYPSLEKEGKTKLTAYLSSKDVARVKIGDSVRYTTTNDAKNQIFLDSTITSIDATATKTEK
GNFFKIEAETHLTSEQATKLRYGLEGRLQMITGKKSYLRYFWDQFLNKG

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=247896 CO686_RS09355 WP_096753745.1 1901798..1903147(+) (comB) [Streptococcus oralis strain FDAARGOS_367]
ATGAAACCAGAATTTTTAGAAAGTGCGGAGTTTTATAATCGTCGTTACCATAATTTTTCCAGTCGGGTGATTTTACCTAT
GTCACTTCTGCTCGTATTTCTGTTAGGATTTGCAGTTTTTGCAGAGAAGGAGATGAGTTTGTCTACCAGAGCGACAGTCG
AACCTAGTCGGATCATTGCCAACATCCAGTCGACTAGCAATCAACGCATTGTGGGCAACTATCTGGAAGAAAACAAGTTG
GTTAAGCAAGGAGATCTGCTCGTTCAGTACCAGCAAGGGGCGGAGGCTGTCCAGGTTGAGGCATATGCCAGTCAATTGGA
GATGTTAAAGGATCAAAAAAAGCAGTTGGGGTATTTGCAATCCAGTTTGAAAGAGGGGAGTGATCAATTTCCAGAGGCGG
ATAAGTTTGGTTATCAGGAGATGTTTCGAGACTATCTCAGCCAAGTTAGTAGTCTTAGGAGTAATGTTTCTCAGCAAAAT
GCCAGCATCTCCTCTCAAAATGCGGCAGCAAGTCAGAGCCAGGCCGAGATTGGCAATCTTATCAGTCAAACAGAGGATAA
AATTCGAGACTATAAAACAGCAAAGTCAGCGATTGAAAAGGGAGATCAACTGGATAGTCAGAATCCAGCCTACTCTTTTT
ACCAGACCTATAAAAATCAAGGTGAAGAAGATCCGCAAGCTAAATCGCAAGTTATTGCGCAAGTGGATGCACAAATTGCC
CAGCTAGAGTCTAGCCTAGCTACGTATCGTGTGCAATATGCAGGTTCTGGAGCTCAACAGGCCCACGCAACGGGACTGGA
TAGTCAACTGGAATCACTCAAGTCTCAGCACTTAGTTAAAGTCGGTCAGGAATTAACTCTTTTGGATCAGAAAATTTTAG
AAGCAGAGTCGGGTAAGAAAGTCCAAGGAGGTCTCCTCGATAAGGGGAAGATTACAGCAAGTGAGGATGGGGTGCTTCAC
CTTAATCCTGAGACTAGCGATTCTACCATGGCCGCAGAAGGAACCCTGCTAGCCCAGCTCTACCCATCCTTGGAAAAAGA
AGGAAAAACCAAACTCACAGCCTATCTCAGTTCAAAAGATGTTGCTAGAGTCAAGATTGGGGATTCTGTCCGTTATACTA
CGACTAATGATGCCAAGAATCAAATTTTCCTGGATTCCACGATTACAAGTATTGATGCGACAGCTACAAAAACTGAAAAA
GGGAATTTCTTTAAAATTGAGGCGGAGACCCATCTGACTTCTGAGCAGGCTACAAAACTTCGCTATGGTTTAGAAGGTCG
TCTACAGATGATTACAGGGAAGAAAAGCTATCTCCGTTATTTTTGGGATCAATTTTTGAATAAAGGGTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus mitis SK321

84.152

99.777

0.84
  comB Streptococcus pneumoniae Rx1

83.259

99.777

0.831
  comB Streptococcus pneumoniae D39

83.259

99.777

0.831
  comB Streptococcus pneumoniae R6

83.259

99.777

0.831
  comB Streptococcus pneumoniae TIGR4

82.812

99.777

0.826
  comB Streptococcus mitis NCTC 12261

82.366

99.777

0.822
  comB Streptococcus gordonii str. Challis substr. CH1

54.867

100

0.552

Multiple sequence alignment