Detailed information NTG0247895

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: CO686_RS09350
• Genome accession: NZ_CP023507
• Coordinates: 1899632..1901785 (+)
• Length: 717 a.a.
• NCBI ID: WP_070800199.1
• Uniprot ID: -
• Organism: Streptococcus oralis strain FDAARGOS_367
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 1894632..1906785

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CO686_RS09310 (CO686_09310)	recO	1895436..1896206 (+)	771	WP_000616143.1	DNA repair protein RecO	-
CO686_RS09315 (CO686_09315)	plsX	1896203..1897195 (+)	993	WP_000717432.1	phosphate acyltransferase PlsX	-
CO686_RS09320 (CO686_09320)	-	1897201..1897437 (+)	237	WP_000136436.1	acyl carrier protein	-
CO686_RS09325 (CO686_09325)	-	1897882..1898025 (+)	144	WP_049549867.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
CO686_RS09330 (CO686_09330)	-	1898040..1898189 (+)	150	WP_033629144.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
CO686_RS10360	-	1898202..1898378 (+)	177	WP_000793177.1	hypothetical protein	-
CO686_RS10365	-	1898528..1898683 (+)	156	WP_000661692.1	hypothetical protein	-
CO686_RS10510 (CO686_09335)	-	1898708..1898920 (+)	213	WP_049549866.1	hypothetical protein	-
CO686_RS09340 (CO686_09340)	-	1899000..1899188 (+)	189	WP_000722238.1	hypothetical protein	-
CO686_RS09345 (CO686_09345)	-	1899213..1899422 (+)	210	WP_000869801.1	hypothetical protein	-
CO686_RS09350 (CO686_09350)	comA	1899632..1901785 (+)	2154	WP_070800199.1	peptide cleavage/export ABC transporter ComA	Regulator
CO686_RS09355 (CO686_09355)	comB	1901798..1903147 (+)	1350	WP_096753745.1	competence pheromone export protein ComB	Regulator
CO686_RS09360 (CO686_09360)	purC	1903316..1904023 (+)	708	WP_007522563.1	phosphoribosylaminoimidazolesuccinocarboxamide synthase	-

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80511.79 Da
• Isoelectric Point: 6.8355

>NTDB_id=247895 CO686_RS09350 WP_070800199.1 1899632..1901785(+) (comA) [Streptococcus oralis strain FDAARGOS_367]
MKFRKRHYRPQVDQMDCGVASLAMVFGYYGSYYSLAHLRELAKTTMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDL
TFPFVAHVLKEGKLLHYYVVIGQDKKHIHIADPDPGVKLTKISRERFAQEWTGVSLFMAPSPDYKPHKEKKQGLLSFLPI
LLKQRGLITNIVLATLLVTLINIVGSYYLQSIIDSYVPDQMRSTLGIISIGLVIVYILQQILSYAQEYLLLILGQRLSID
VILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSIIDALSSTILSIFLDVSTILIISLVLFSQNMTLFFISLLALPIYTV
IIFAFMKPFEKMNRDTMEANAVLSSSIIEDINGIETIKSLTSESSRYQKIDKEFVAYLKKSFTYSRAESQQKALKKVAQL
LLNVAVLWLGAILVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQTAQVANNRLNEVYLVASEFEEQKTVEDLSMM
KGEMTFKQVHYKYGYGRDVLSDINLTIPQGSKMAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYI
NYLPQQPYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISGGQRQRIALARALLTDA
PVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAERTEKVVVLDQGKIVEEGTHADLLAQDGFYAHLVNS

Nucleotide

• Length: 2154 bp

>NTDB_id=247895 CO686_RS09350 WP_070800199.1 1899632..1901785(+) (comA) [Streptococcus oralis strain FDAARGOS_367]
ATGAAATTTAGGAAAAGGCACTATCGTCCCCAGGTGGATCAGATGGATTGTGGCGTGGCTTCTTTGGCTATGGTCTTTGG
TTACTACGGTAGTTATTACTCCTTGGCTCATCTACGAGAGTTAGCCAAGACGACCATGGATGGGACGACCGCTTTGGGAC
TTGTAAAGGTGGCAGAGGAGATTGGATTTGAGACGCGGGCTATCAAGGCGGATATGACGCTCTTTGATTTGCCAGATTTG
ACCTTTCCTTTTGTGGCTCATGTGCTCAAGGAAGGGAAGTTGCTCCACTACTATGTGGTGATAGGTCAGGATAAAAAGCA
TATTCATATCGCTGATCCGGATCCTGGTGTCAAGCTGACCAAGATTTCCCGTGAGCGATTTGCGCAAGAATGGACAGGAG
TCAGTCTCTTTATGGCTCCGTCTCCAGACTATAAACCCCATAAGGAGAAAAAACAGGGGCTCCTATCCTTCTTGCCAATT
TTGCTCAAACAGCGGGGCTTGATTACCAATATCGTCCTAGCGACACTCTTGGTGACCTTGATCAATATCGTGGGTTCCTA
CTATCTTCAGTCCATCATTGATAGTTACGTACCAGACCAGATGCGCTCGACACTGGGTATTATCTCTATTGGGCTGGTCA
TCGTCTATATCCTCCAGCAAATTTTGTCTTATGCCCAGGAATATCTCCTACTGATACTTGGGCAACGCTTATCGATTGAC
GTGATTTTGTCCTACATCAAGCATGTTTTTCACCTGCCAATGTCCTTTTTTGCGACACGCAGGACAGGAGAAATCGTGTC
TCGTTTTACAGATGCCAATAGTATCATCGATGCGCTGTCGTCGACCATTCTGTCGATTTTCCTAGATGTGTCGACGATTT
TGATTATCTCGCTGGTCTTGTTTTCACAAAATATGACGCTCTTTTTCATTAGTCTACTTGCGCTTCCCATCTATACAGTG
ATTATCTTTGCCTTTATGAAGCCTTTTGAAAAGATGAATCGGGATACCATGGAAGCCAATGCGGTTCTGTCTTCCTCTAT
CATCGAGGACATCAACGGTATTGAGACCATTAAGTCTTTGACCAGTGAAAGTTCGCGCTATCAAAAGATTGACAAGGAAT
TTGTAGCTTATCTGAAAAAATCCTTTACCTATAGTCGGGCAGAAAGCCAGCAAAAGGCTCTGAAAAAAGTTGCCCAGCTC
CTGCTCAATGTTGCCGTTCTCTGGCTAGGAGCCATTCTTGTTATGGACGGGAAAATGAGTTTGGGCCAGCTGATTACCTA
TAATACTTTGCTTGTTTACTTTACCAATCCTTTGGAAAATATCATTAACCTACAAACCAAACTTCAGACAGCGCAGGTTG
CCAATAATCGCTTAAATGAGGTTTATCTAGTAGCTTCGGAGTTTGAGGAGCAGAAAACAGTCGAAGATTTGAGCATGATG
AAGGGAGAGATGACCTTTAAACAAGTTCACTATAAGTATGGCTATGGGCGTGATGTCTTGTCGGATATCAATTTGACCAT
TCCACAAGGGTCTAAGATGGCTTTTGTGGGGATTTCAGGTTCGGGTAAGACCACCTTAGCCAAGATGATGGTTAATTTTT
ACGACCCAAGTCAGGGAGAGATTAGTCTGGGTGGTGTCAATCTTAATCAGATTGATAAAAAGGCCCTGCGCCAGTATATC
AACTACCTGCCTCAACAGCCCTATGTCTTTAACGGAACGATTTTGGAGAATCTTCTCCTTGGAGCCAAGGAGGGGACGAC
TCAGGAAGATATCTTACGAGCAGTCGAGTTGGCAGAGATTCGGGAGGATATTGAGCGCATGCCTCTGAATTATCAGACAG
AATTGACTTCGGATGGGGCTGGAATTTCTGGTGGGCAACGGCAGAGAATCGCTCTGGCGCGTGCTCTCTTGACGGATGCA
CCTGTCTTGATCTTGGACGAGGCGACTAGCAGTTTGGATATTTTGACAGAGAAGCGGATCGTGGATAATCTCATGGCTTT
AGATAAGACCTTGATTTTCATCGCCCATCGCTTGACCATCGCTGAGCGGACAGAAAAGGTTGTTGTTTTGGATCAGGGCA
AGATTGTCGAAGAGGGCACCCATGCAGATTTGCTTGCACAGGATGGCTTTTACGCCCATTTGGTGAATAGCTAG

Domains

Predicted by InterproScan.

• ABC transporter transmembrane region (ABC_membrane) (170-438)

• ABC transporter (ABC_tran) (500-650)

• Peptidase C39 family (Peptidase_C39) (7-142)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus mitis NCTC 12261	94.7	100	0.947
comA	Streptococcus mitis SK321	94.421	100	0.944
comA	Streptococcus pneumoniae Rx1	94.421	100	0.944
comA	Streptococcus pneumoniae D39	94.421	100	0.944
comA	Streptococcus pneumoniae R6	94.421	100	0.944
comA	Streptococcus pneumoniae TIGR4	94.003	100	0.94
comA	Streptococcus gordonii str. Challis substr. CH1	80.195	100	0.802
comA/nlmT	Streptococcus mutans UA159	64.296	100	0.643