Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   CO680_RS06800 Genome accession   NZ_CP023501
Coordinates   1363058..1364275 (-) Length   405 a.a.
NCBI ID   WP_002828715.1    Uniprot ID   C5RAW5
Organism   Weissella paramesenteroides strain FDAARGOS_414     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1358058..1369275
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CO680_RS06780 (CO680_06780) rpoE 1359211..1359804 (-) 594 WP_002828710.1 DNA-directed RNA polymerase subunit delta -
  CO680_RS06785 (CO680_06785) yidA 1359884..1360720 (-) 837 WP_002828711.1 sugar-phosphatase -
  CO680_RS06790 (CO680_06790) - 1360736..1362112 (-) 1377 WP_002828713.1 HD domain-containing protein -
  CO680_RS06795 (CO680_06795) - 1362216..1362653 (+) 438 WP_002828714.1 DUF1934 domain-containing protein -
  CO680_RS06800 (CO680_06800) htrA 1363058..1364275 (-) 1218 WP_002828715.1 trypsin-like peptidase domain-containing protein Regulator
  CO680_RS06805 (CO680_06805) - 1364384..1365184 (-) 801 WP_002828716.1 MBL fold metallo-hydrolase -
  CO680_RS06810 (CO680_06810) yycI 1365397..1366218 (-) 822 WP_002828717.1 two-component system regulatory protein YycI -
  CO680_RS06815 (CO680_06815) yycH 1366219..1367571 (-) 1353 WP_040760986.1 two-component system activity regulator YycH -

Sequence

Protein


Download         Length: 405 a.a.        Molecular weight: 41552.16 Da        Isoelectric Point: 5.2273

>NTDB_id=247788 CO680_RS06800 WP_002828715.1 1363058..1364275(-) (htrA) [Weissella paramesenteroides strain FDAARGOS_414]
MKLSSESKIVVIGVVAGLIGGGVAAGGVTYFSQDDQSSVTTSKTTAVKVKNNNVKGTSSATKAFKKVSGAVVSVINLQKQ
QSLQSGIYGSTTDSSSSSDSSDLQTASEGSGVIYKKDNDTAYIVTNNHVVADSNAIQVLLSDGTKLTAKLVGTDEQTDLA
VLKVSSSKINEVADFADSSKTEAGQSVLAIGSPLGSDYATSVTEGIISATKRQVDATDESGNSLGKATVLQTDAAINPGN
SGGPLVNLAGQVVGINSMKLASSEDGTSVEGMGFAIPSNTVVSIINELEKNGKIERPALGVSMVDLSNVSTSDQSNVLHL
PSSVSGGVVVVDTEDNSPAANAGLTQYDVITKIDGKRVSNSGDLRDALYKHKIGDSVQLTYYHKGKEKTVTVKLNKSTSS
LSSAQ

Nucleotide


Download         Length: 1218 bp        

>NTDB_id=247788 CO680_RS06800 WP_002828715.1 1363058..1364275(-) (htrA) [Weissella paramesenteroides strain FDAARGOS_414]
ATGAAATTATCATCTGAATCAAAAATTGTGGTAATTGGTGTTGTCGCTGGACTAATCGGTGGGGGTGTTGCTGCTGGTGG
TGTGACATATTTTTCACAGGATGATCAGTCATCTGTGACTACTAGTAAAACAACAGCGGTTAAAGTAAAAAATAATAATG
TTAAGGGAACTTCCAGTGCAACAAAAGCCTTTAAGAAGGTTTCAGGGGCGGTTGTTTCGGTTATTAATTTGCAAAAACAA
CAATCTTTACAGTCGGGGATTTATGGTAGCACAACAGACAGCTCTTCAAGTAGTGATTCATCAGATCTTCAAACGGCATC
AGAAGGTTCGGGTGTCATTTATAAAAAAGACAATGATACGGCCTATATTGTGACTAATAATCATGTTGTTGCGGATTCAA
ATGCCATTCAAGTTTTGTTGAGCGACGGAACAAAATTAACAGCGAAACTAGTAGGAACTGATGAACAAACTGATTTGGCT
GTCTTGAAAGTGTCATCAAGTAAAATTAATGAAGTTGCTGATTTTGCGGACTCTTCTAAGACAGAAGCTGGCCAATCAGT
ATTAGCGATTGGATCACCTTTAGGATCTGACTATGCAACGTCAGTAACGGAGGGAATCATTTCTGCTACAAAGCGACAAG
TTGATGCGACCGATGAAAGCGGCAACTCTTTGGGAAAGGCCACTGTTCTACAGACTGATGCAGCGATAAATCCTGGTAAT
TCGGGTGGCCCATTGGTTAATTTAGCTGGACAGGTAGTGGGAATCAACTCAATGAAATTAGCATCTTCTGAAGATGGTAC
CTCTGTTGAAGGTATGGGTTTTGCTATCCCTTCAAATACAGTTGTAAGTATTATTAACGAACTTGAGAAGAACGGAAAGA
TCGAGCGTCCTGCATTAGGTGTTTCAATGGTCGATTTGAGTAATGTTTCTACAAGTGACCAAAGTAATGTTTTGCACTTA
CCATCTAGTGTATCAGGAGGTGTCGTAGTTGTTGATACTGAGGATAACTCGCCAGCAGCTAATGCTGGATTGACTCAGTA
TGACGTGATTACCAAAATTGATGGTAAGAGGGTATCAAACTCAGGTGATCTACGTGATGCACTATATAAACATAAAATTG
GCGATTCTGTACAGTTAACTTACTATCACAAAGGCAAAGAAAAAACTGTAACAGTCAAGTTAAATAAGTCGACCAGTTCG
TTAAGTAGTGCGCAATAA

Domains

Predicted by InterproScan.

Peptidase family M50 (Peptidase_M50)

(9-398)

Trypsin-like peptidase domain (Trypsin_2)

(109-255)

PDZ domain (PDZ_2)

(297-394)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB C5RAW5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus gordonii str. Challis substr. CH1

49.367

97.531

0.481
  htrA Streptococcus pneumoniae D39

46.701

97.284

0.454
  htrA Streptococcus pneumoniae R6

46.701

97.284

0.454
  htrA Streptococcus pneumoniae Rx1

46.701

97.284

0.454
  htrA Streptococcus pneumoniae TIGR4

46.701

97.284

0.454
  htrA Streptococcus mitis NCTC 12261

46.447

97.284

0.452
  htrA Streptococcus mutans UA159

51.862

86.173

0.447

Multiple sequence alignment