Detailed information NTG0247389

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: CO204_RS00350
• Genome accession: NZ_CP023477
• Coordinates: 54481..55395 (+)
• Length: 304 a.a.
• NCBI ID: WP_024784317.1
• Uniprot ID: -
• Organism: Streptococcus mutans strain LAR01
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 49481..60395

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CO204_RS00320 (CO204_00320)	-	49834..50053 (+)	220	Protein_39	phosphoribosylaminoimidazole carboxylase	-
CO204_RS00325 (CO204_00325)	-	50056..50745 (+)	690	WP_106006635.1	aspartate/glutamate racemase family protein	-
CO204_RS00330 (CO204_00330)	-	50756..51172 (+)	417	WP_106006636.1	SRPBCC family protein	-
CO204_RS00335 (CO204_00335)	-	51200..52075 (+)	876	WP_002264675.1	hypothetical protein	-
CO204_RS00340 (CO204_00340)	purB	52092..53390 (+)	1299	WP_106006637.1	adenylosuccinate lyase	-
CO204_RS00345 (CO204_00345)	-	53410..54096 (+)	687	WP_106006638.1	DNA alkylation repair protein	-
CO204_RS00350 (CO204_00350)	comR	54481..55395 (+)	915	WP_024784317.1	helix-turn-helix domain-containing protein	Regulator
CO204_RS00355 (CO204_00355)	-	55931..57772 (-)	1842	WP_106006639.1	carbohydrate-binding domain-containing protein	-
CO204_RS00360 (CO204_00360)	ruvB	58107..59102 (+)	996	WP_002269367.1	Holliday junction branch migration DNA helicase RuvB	-
CO204_RS00365 (CO204_00365)	-	59140..59565 (+)	426	WP_002264681.1	low molecular weight protein-tyrosine-phosphatase	-
CO204_RS00370 (CO204_00370)	-	59630..60013 (+)	384	WP_011074470.1	membrane protein	-

Sequence

Protein

• Length: 304 a.a.
• Molecular weight: 35202.28 Da
• Isoelectric Point: 5.0071

>NTDB_id=247389 CO204_RS00350 WP_024784317.1 54481..55395(+) (comR) [Streptococcus mutans strain LAR01]
MLKDFGKKIKSLRLEKGLTKEAVCLDESQLSTRQLTRIESGQSTPTLNKAVYIAGRLGVTLGYLTDGENVELPSRYKELK
YLLLRTPTYGDQQRLAEKETYFDEIFSQFYDDLPEEEQLIIDGLQSKLDIHFSDNIDFGVGILNDYFDQILRKTNYQVND
LILIDLYFSCLTVSGLDSAIFDSRKYNQLLETLLKQVDCLPLEDLFVLNNVLLNNFGLLLELKKYDFVKQLIAVSNKIMA
RTHDFQKKPIVNLLTWKHHLFVEKNYAEAKKSYDAAILFAQLTENINLRENLEKEWQKDSQNGT

Nucleotide

• Length: 915 bp

>NTDB_id=247389 CO204_RS00350 WP_024784317.1 54481..55395(+) (comR) [Streptococcus mutans strain LAR01]
ATGTTAAAAGATTTTGGGAAGAAAATTAAGAGCCTGAGGTTAGAAAAGGGGCTGACCAAAGAAGCTGTCTGCCTTGATGA
ATCTCAATTGTCAACACGGCAGTTGACCAGAATTGAATCAGGACAGTCTACGCCAACTCTTAATAAAGCTGTTTATATTG
CAGGACGTTTAGGAGTGACGCTTGGCTATTTAACGGACGGAGAAAATGTTGAGTTACCCAGTCGTTATAAAGAACTAAAG
TATTTATTATTACGAACGCCAACCTATGGCGACCAACAAAGATTAGCTGAAAAAGAAACCTATTTTGACGAGATTTTTAG
TCAGTTTTATGATGATTTGCCTGAAGAAGAACAATTGATTATTGATGGCTTACAATCGAAACTAGATATTCATTTTAGTG
ACAATATCGATTTTGGCGTTGGTATTTTAAATGACTATTTTGATCAGATTTTAAGAAAAACCAATTATCAGGTCAATGAT
TTGATTCTGATTGATCTCTATTTTTCCTGCTTAACTGTTAGTGGTTTGGATTCAGCTATTTTTGATTCAAGAAAATATAA
TCAATTATTGGAGACATTGCTTAAGCAGGTAGACTGCCTTCCATTGGAAGATCTTTTCGTTTTAAATAATGTTTTATTGA
ATAATTTTGGACTCCTCTTAGAATTGAAAAAATATGATTTTGTTAAGCAGCTTATTGCTGTCAGCAATAAAATCATGGCT
AGAACTCATGATTTTCAAAAAAAGCCTATTGTTAATCTTCTGACATGGAAGCATCATTTATTTGTTGAAAAAAATTATGC
GGAAGCTAAAAAGAGCTATGATGCTGCTATCTTATTTGCCCAGTTAACAGAAAACATTAATTTAAGAGAAAATTTGGAGA
AAGAATGGCAAAAAGATTCTCAGAACGGGACATAA

Domains

Predicted by InterproScan.

• ComR tetratricopeptide (ComR_TPR) (73-296)

• Helix-turn-helix (HTH_3) (9-64)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus mutans UA159	99.342	100	0.993
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	52.431	94.737	0.497
comR	Streptococcus pyogenes MGAS8232	46.358	99.342	0.461
comR	Streptococcus pyogenes MGAS315	46.823	98.355	0.461
comR	Streptococcus suis P1/7	43.478	98.355	0.428
comR	Streptococcus suis 05ZYH33	43.478	98.355	0.428
comR	Streptococcus suis D9	37.333	98.684	0.368