Detailed information NTG0024543

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: M5005_RS04420
• Genome accession: NC_007297
• Coordinates: 874211..875047 (+)
• Length: 278 a.a.
• NCBI ID: WP_010922314.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes MGAS5005
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 869211..880047

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
M5005_RS04390 (M5005_Spy0878)	-	869765..870133 (+)	369	WP_010922310.1	hypothetical protein	-
M5005_RS04395 (M5005_Spy0879)	-	870183..871094 (-)	912	WP_010922311.1	diacylglycerol/lipid kinase family protein	-
M5005_RS04400 (M5005_Spy0880)	trhA	871211..871861 (-)	651	WP_002984629.1	PAQR family membrane homeostasis protein TrhA	-
M5005_RS04405 (M5005_Spy0881)	-	871858..872298 (-)	441	WP_002989774.1	DUF1836 domain-containing protein	-
M5005_RS04410 (M5005_Spy0882)	ylqF	872517..873365 (+)	849	WP_010922312.1	ribosome biogenesis GTPase YlqF	-
M5005_RS04415 (M5005_Spy0883)	-	873355..874146 (+)	792	WP_011285534.1	ribonuclease HII	-
M5005_RS04420 (M5005_Spy0884)	dprA	874211..875047 (+)	837	WP_010922314.1	DNA-processing protein DprA	Machinery gene
M5005_RS04425 (M5005_Spy0885)	topA	875154..877283 (+)	2130	WP_010922315.1	type I DNA topoisomerase	-
M5005_RS09835	-	877358..878240 (-)	883	Protein_824	LysR family transcriptional regulator	-
M5005_RS04435 (M5005_Spy0889)	-	878253..878798 (+)	546	Protein_825	PTS sugar transporter subunit IIC	-
M5005_RS04440 (M5005_Spy0890)	-	878813..879805 (+)	993	WP_010922317.1	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30973.93 Da
• Isoelectric Point: 9.0514

>NTDB_id=24543 M5005_RS04420 WP_010922314.1 874211..875047(+) (dprA) [Streptococcus pyogenes MGAS5005]
MNHFELYKLKKAGLTNKNILNILDYQKHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQNLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=24543 M5005_RS04420 WP_010922314.1 874211..875047(+) (dprA) [Streptococcus pyogenes MGAS5005]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAATTTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACTATC
GCTATTATTGGAACAGGATTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.266	100	0.673
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis SK321	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.072	100	0.601
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367