Detailed information NTG0024487

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: M28_RS04470
• Genome accession: NC_007296
• Coordinates: 876634..877470 (+)
• Length: 278 a.a.
• NCBI ID: WP_002995009.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes MGAS6180
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 871634..882470

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
M28_RS04440 (M28_Spy0852)	-	872122..872556 (+)	435	WP_021340932.1	hypothetical protein	-
M28_RS04445 (M28_Spy0853)	-	872606..873517 (-)	912	WP_011284791.1	diacylglycerol/lipid kinase family protein	-
M28_RS04450 (M28_Spy0854)	-	873634..874284 (-)	651	WP_002984629.1	PAQR family membrane homeostasis protein TrhA	-
M28_RS04455 (M28_Spy0855)	-	874281..874721 (-)	441	WP_002984627.1	DUF1836 domain-containing protein	-
M28_RS04460 (M28_Spy0856)	ylqF	874940..875788 (+)	849	WP_002984625.1	ribosome biogenesis GTPase YlqF	-
M28_RS04465 (M28_Spy0857)	-	875778..876569 (+)	792	WP_011888871.1	ribonuclease HII	-
M28_RS04470 (M28_Spy0858)	dprA	876634..877470 (+)	837	WP_002995009.1	DNA-processing protein DprA	Machinery gene
M28_RS04475 (M28_Spy0859)	topA	877577..879706 (+)	2130	WP_011284793.1	type I DNA topoisomerase	-
M28_RS09775	-	879781..880638 (-)	858	Protein_818	LysR family transcriptional regulator	-
M28_RS04490 (M28_Spy0862)	-	880678..881223 (+)	546	Protein_819	PTS sugar transporter subunit IIC	-
M28_RS04495 (M28_Spy0863)	-	881238..882230 (+)	993	WP_021340798.1	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30970.91 Da
• Isoelectric Point: 8.8230

>NTDB_id=24487 M28_RS04470 WP_002995009.1 876634..877470(+) (dprA) [Streptococcus pyogenes MGAS6180]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKIEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=24487 M28_RS04470 WP_002995009.1 876634..877470(+) (dprA) [Streptococcus pyogenes MGAS6180]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATAGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACTATC
GCTATTATTGGAACAGGATTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.626	100	0.676
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis SK321	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.432	100	0.604
dprA	Lactococcus lactis subsp. cremoris KW2	57.554	100	0.576
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367