Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   CK496_RS01160 Genome accession   NZ_CP023074
Coordinates   222280..223560 (-) Length   426 a.a.
NCBI ID   WP_086270550.1    Uniprot ID   A0AA91PR58
Organism   Enterococcus thailandicus strain a523     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 217280..228560
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CK496_RS01130 (CK496_01130) - 217674..218627 (-) 954 WP_095803367.1 glycosyltransferase family 2 protein -
  CK496_RS01135 (CK496_01135) - 218816..219178 (-) 363 WP_071868550.1 PepSY domain-containing protein -
  CK496_RS01140 (CK496_01140) pepA 219374..220453 (+) 1080 WP_067483260.1 glutamyl aminopeptidase -
  CK496_RS01145 (CK496_01145) - 220606..220926 (+) 321 WP_067483258.1 thioredoxin family protein -
  CK496_RS01150 (CK496_01150) - 220948..221409 (+) 462 WP_067483256.1 universal stress protein -
  CK496_RS01155 (CK496_01155) ytpR 221604..222209 (+) 606 WP_095803368.1 YtpR family tRNA-binding protein -
  CK496_RS01160 (CK496_01160) htrA 222280..223560 (-) 1281 WP_086270550.1 trypsin-like peptidase domain-containing protein Regulator
  CK496_RS01165 (CK496_01165) rlmH 223994..224473 (+) 480 WP_071868554.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  CK496_RS01170 (CK496_01170) - 224558..225067 (+) 510 WP_095803369.1 DUF1456 family protein -
  CK496_RS01175 (CK496_01175) - 225167..225817 (+) 651 WP_071868555.1 hypothetical protein -
  CK496_RS01180 (CK496_01180) - 226270..227208 (+) 939 WP_071868556.1 2-dehydropantoate 2-reductase -
  CK496_RS01185 (CK496_01185) - 227221..228273 (+) 1053 WP_071868557.1 PTS sugar transporter subunit IIC -

Sequence

Protein


Download         Length: 426 a.a.        Molecular weight: 44541.50 Da        Isoelectric Point: 4.3821

>NTDB_id=244701 CK496_RS01160 WP_086270550.1 222280..223560(-) (htrA) [Enterococcus thailandicus strain a523]
MDKKDVTPKMKKNKYGFWKKLGLGLVGGVLGGLITAGIFYVAMGSSFTTSSTSASGNQNSAGETVVENVKVNVESDITSA
VDKVQGAVVSVINLQNQNQSSEFGQLFGQQEQSSSDEALEAYSEGSGVIYKKDGDSAYIVTNNHVVDGQQGLEVLLKDGS
KVKAELVGTDAYSDLAVLKISADKVDTVASFGDSESLKVGEPAIAIGSPLGSAYANSVTSGIVSSLNRQVTSTNESNETV
NINAIQTDAAINPGNSGGPLVNIEGQVIGINSSKIASTSESSSDVNVEGMGFAIPSNDVVNVINQLEKDGKVTRPALGIT
MVDLSAVSTQQQEQVLKIPTSVTNGVIVTNVQAATPAEKAGLKQYDVITKIDDTEVSSGVELQTALYKKKVGDSVKVTYY
RGSEEKTATVELTIDQSSLKQNNSNE

Nucleotide


Download         Length: 1281 bp        

>NTDB_id=244701 CK496_RS01160 WP_086270550.1 222280..223560(-) (htrA) [Enterococcus thailandicus strain a523]
ATGGATAAAAAAGATGTGACACCTAAAATGAAAAAAAATAAGTATGGATTTTGGAAGAAGTTAGGCCTCGGACTTGTTGG
TGGCGTCCTTGGTGGATTGATTACTGCAGGAATTTTTTACGTCGCTATGGGATCGTCTTTTACAACTTCTTCGACAAGCG
CAAGTGGAAATCAAAATTCTGCTGGTGAGACAGTCGTTGAGAATGTCAAAGTAAACGTTGAATCAGATATTACTAGCGCT
GTTGATAAAGTACAAGGCGCTGTTGTTTCAGTAATCAATTTACAAAATCAAAATCAATCAAGTGAATTCGGTCAGCTCTT
TGGACAACAGGAACAAAGCAGCTCTGATGAAGCTTTAGAAGCTTATAGTGAAGGCAGTGGTGTCATTTATAAGAAAGATG
GCGACTCTGCCTACATCGTTACAAATAATCACGTGGTTGATGGGCAACAAGGCTTGGAAGTTTTACTGAAAGATGGCAGT
AAAGTGAAGGCTGAACTAGTTGGAACAGACGCCTACTCTGACTTAGCTGTATTAAAAATCAGTGCTGACAAAGTCGACAC
AGTCGCTTCATTTGGCGACTCTGAATCCTTAAAAGTTGGTGAACCTGCTATTGCGATTGGCTCACCATTAGGCTCAGCTT
ATGCTAACTCAGTAACTTCAGGTATCGTGTCTTCTTTAAATCGTCAAGTAACTAGTACGAATGAATCAAACGAAACAGTC
AACATCAACGCAATCCAAACAGATGCTGCAATCAATCCTGGTAATTCAGGTGGCCCATTAGTAAACATTGAAGGACAAGT
AATCGGAATCAATTCAAGTAAGATTGCTAGTACCTCAGAATCTTCCTCTGATGTGAATGTGGAAGGAATGGGTTTTGCAA
TTCCAAGTAATGATGTAGTAAATGTAATCAATCAATTAGAAAAAGACGGAAAAGTAACCCGTCCAGCTCTTGGAATTACG
ATGGTCGATTTATCTGCTGTTTCTACACAACAACAAGAACAAGTCTTGAAGATTCCAACTTCTGTAACAAATGGTGTCAT
TGTAACCAATGTTCAAGCAGCTACTCCTGCTGAAAAGGCGGGATTGAAACAATACGATGTTATCACTAAGATTGATGATA
CCGAAGTTTCTTCTGGTGTTGAGTTACAAACTGCACTTTACAAGAAAAAAGTCGGCGACAGTGTCAAAGTGACTTATTAC
CGAGGATCTGAAGAAAAAACTGCTACGGTAGAGTTGACAATCGATCAATCTTCATTGAAACAAAATAATTCGAATGAGTA
A

Domains

Predicted by InterproScan.

Trypsin-like peptidase domain (Trypsin_2)

(125-270)

PDZ domain (PDZ_2)

(315-412)

Peptidase family M50 (Peptidase_M50)

(13-416)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus gordonii str. Challis substr. CH1

54.034

96.009

0.519
  htrA Streptococcus mutans UA159

56.533

88.028

0.498
  htrA Streptococcus mitis NCTC 12261

51.724

95.305

0.493
  htrA Streptococcus pneumoniae TIGR4

52.273

92.958

0.486
  htrA Streptococcus pneumoniae Rx1

52.273

92.958

0.486
  htrA Streptococcus pneumoniae D39

52.273

92.958

0.486
  htrA Streptococcus pneumoniae R6

52.273

92.958

0.486

Multiple sequence alignment