Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/blpH   Type   Regulator
Locus tag   STR_RS11400 Genome accession   NC_006449
Coordinates   1496627..1497430 (+) Length   267 a.a.
NCBI ID   WP_224103634.1    Uniprot ID   -
Organism   Streptococcus thermophilus CNRZ1066     
Function   phosphorylation of ComE; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1491627..1502430
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STR_RS10255 - 1493331..1494721 (+) 1391 Protein_1491 IS3-like element ISSth1b family transposase -
  STR_RS07895 (str1685) - 1494867..1495109 (-) 243 WP_011227518.1 Blp family class II bacteriocin -
  STR_RS07900 (str1686) comE/blpR 1495359..1496090 (+) 732 WP_002948869.1 LytR/AlgR family response regulator transcription factor Regulator
  STR_RS11400 comD/blpH 1496627..1497430 (+) 804 WP_224103634.1 ATP-binding protein Regulator
  STR_RS07910 (str1688) - 1497448..1497609 (-) 162 WP_011226496.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  STR_RS07915 (str1689) - 1497624..1498992 (-) 1369 Protein_1496 bacteriocin secretion accessory protein -
  STR_RS07920 (str1691) comA/nlmT 1499008..1501161 (-) 2154 WP_041827095.1 peptide cleavage/export ABC transporter Regulator

Sequence

Protein


Download         Length: 267 a.a.        Molecular weight: 30835.17 Da        Isoelectric Point: 4.8309

>NTDB_id=24416 STR_RS11400 WP_224103634.1 1496627..1497430(+) (comD/blpH) [Streptococcus thermophilus CNRZ1066]
MYLENTTHSSTLELRKLCVVISLVLFFIMIVFLERNIREMIQGQLDFQKNLQLENLYTYNKHIECLYNSVRSFRHDYSNL
LVTLRLGIDKDDMDIVKEVYDSVLQESDKRLNTRNFDLARLVNIQDNTLKSLLSAKVLQAEEEGIEAQISIPEPIHLIGM
EILDFIIVTSIFLDNAIEGAIQTQNHKITISFWEDHRSQLLSISNTISEEQTETKTIFERGVSNKGRERGIGLANVTEIL
DNYINVNLETQSNNFSFTQQLTITKKA

Nucleotide


Download         Length: 804 bp        

>NTDB_id=24416 STR_RS11400 WP_224103634.1 1496627..1497430(+) (comD/blpH) [Streptococcus thermophilus CNRZ1066]
ATGTATCTTGAAAACACTACTCACTCTTCAACTTTGGAGCTTCGAAAACTCTGTGTTGTTATTTCACTTGTCCTCTTCTT
CATTATGATTGTCTTTTTAGAAAGAAACATTCGTGAAATGATTCAAGGACAATTGGACTTCCAGAAAAATCTCCAGCTAG
AGAATCTCTACACCTACAATAAACATATTGAATGTCTCTACAATTCTGTTCGTAGTTTTAGACACGATTATAGTAATCTC
TTAGTCACATTACGATTGGGGATAGATAAAGACGATATGGATATTGTCAAAGAAGTCTATGATAGTGTGCTTCAAGAATC
CGATAAACGATTAAATACAAGAAACTTTGACTTAGCTAGACTCGTTAATATTCAGGATAATACTTTGAAAAGCCTTCTGT
CCGCAAAAGTTTTACAAGCAGAAGAAGAAGGTATTGAAGCTCAGATTAGCATCCCAGAACCCATCCACTTGATTGGGATG
GAGATTCTGGACTTCATTATCGTCACTTCTATTTTTTTAGATAACGCTATTGAAGGTGCCATTCAAACTCAAAACCATAA
AATTACTATTAGCTTTTGGGAAGATCATCGTTCACAGCTATTATCTATTAGCAATACCATAAGTGAAGAACAAACAGAAA
CTAAAACCATATTTGAAAGAGGTGTCTCCAACAAGGGACGAGAGCGAGGCATTGGCCTTGCTAATGTCACAGAAATCTTA
GATAACTATATCAATGTAAACTTAGAAACACAGAGTAACAATTTCTCATTCACACAACAATTAACAATAACTAAAAAGGC
CTAA

Domains

Predicted by InterProScan.

GHKL domain (HATPase_c_5)

(160-263)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/blpH Streptococcus mutans UA159

38.189

95.131

0.363

Multiple sequence alignment