Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   CJZ72_RS06585 Genome accession   NZ_CP022930
Coordinates   1369074..1370357 (-) Length   427 a.a.
NCBI ID   WP_081133846.1    Uniprot ID   A0A367CHU7
Organism   Enterococcus durans strain BDGP3     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1364074..1375357
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CJZ72_RS06555 (CJZ72_06545) - 1364121..1365089 (-) 969 WP_081133841.1 glycosyltransferase family 2 protein -
  CJZ72_RS06560 (CJZ72_06550) - 1365270..1365620 (-) 351 WP_005875490.1 PepSY domain-containing protein -
  CJZ72_RS06565 (CJZ72_06555) pepA 1365818..1366897 (+) 1080 WP_081133843.1 glutamyl aminopeptidase -
  CJZ72_RS06570 (CJZ72_06560) - 1367202..1367522 (+) 321 WP_005875492.1 thioredoxin family protein -
  CJZ72_RS06575 (CJZ72_06565) - 1367544..1368011 (+) 468 WP_081133844.1 universal stress protein -
  CJZ72_RS06580 (CJZ72_06570) ytpR 1368352..1368969 (+) 618 WP_081133845.1 YtpR family tRNA-binding protein -
  CJZ72_RS06585 (CJZ72_06575) htrA 1369074..1370357 (-) 1284 WP_081133846.1 S1C family serine protease Regulator
  CJZ72_RS06590 (CJZ72_06580) rlmH 1370785..1371264 (+) 480 WP_081133847.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  CJZ72_RS06595 (CJZ72_06585) - 1371349..1371858 (+) 510 WP_002296569.1 DUF1456 family protein -
  CJZ72_RS06600 (CJZ72_06590) - 1371958..1372608 (+) 651 WP_002312640.1 hypothetical protein -
  CJZ72_RS06605 (CJZ72_06595) - 1373059..1373997 (+) 939 WP_002291914.1 2-dehydropantoate 2-reductase -
  CJZ72_RS06610 (CJZ72_06600) - 1374010..1375062 (+) 1053 WP_002291912.1 PTS sugar transporter subunit IIC -

Sequence

Protein


Download         Length: 427 a.a.        Molecular weight: 44775.75 Da        Isoelectric Point: 4.5954

>NTDB_id=243538 CJZ72_RS06585 WP_081133846.1 1369074..1370357(-) (htrA) [Enterococcus durans strain BDGP3]
MDRKDVTSKMKKKNNGLWRKLGLGLVGGVIGGLLTAGIFYAALGNGHSNTSAGGNQNSSGETVVENVKVNVDSDITSAVD
KVQDAVVSVINLQSQNQSNDFGKLFGQQQQSTEDSDLEASSEGSGVIYKKEGNTSYIVTNNHVVDGQQGLEVLLKDGTKV
KAELVGTDAYSDLAVLKIQSDKVDKVASFGDSSALKVGEPAIAIGSPLGSEYANSVTSGIVSSLNRQVTSTNESNETVNI
NAIQTDAAINPGNSGGPLINIEGQVIGINSSKIATTSESSSGVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALGITMY
DLSYVSTQQKEQVLKIPSSVTNGVIVASVQPATPAEKAGLKQYDVITKIDDTEVSSGVELQSALYKKKVGDTVKITYYQE
KDEKTATVELTIDQSALKQNQSSNSGN

Nucleotide


Download         Length: 1284 bp        

>NTDB_id=243538 CJZ72_RS06585 WP_081133846.1 1369074..1370357(-) (htrA) [Enterococcus durans strain BDGP3]
ATGGATAGAAAAGATGTGACATCAAAAATGAAAAAGAAAAATAATGGTCTTTGGCGCAAACTTGGACTAGGTTTAGTCGG
TGGTGTGATTGGAGGATTATTAACAGCGGGTATTTTTTATGCTGCATTAGGAAATGGTCACTCCAATACGAGTGCTGGGG
GTAACCAGAATTCGTCAGGTGAAACTGTTGTAGAAAATGTCAAAGTGAATGTAGATTCAGATATTACTAGTGCTGTAGAT
AAAGTACAAGATGCGGTAGTTTCCGTTATCAACTTGCAAAGTCAAAATCAATCGAACGATTTTGGCAAACTATTTGGGCA
ACAGCAGCAAAGTACTGAAGATAGTGATCTAGAAGCTTCTAGTGAAGGGAGTGGCGTGATTTACAAAAAAGAGGGCAACA
CTTCATATATCGTAACAAATAACCACGTAGTTGATGGGCAACAAGGATTAGAAGTTTTGCTCAAAGATGGGACAAAAGTC
AAAGCAGAATTAGTTGGAACTGATGCTTATTCTGATTTAGCTGTATTGAAAATCCAATCAGATAAAGTGGATAAAGTTGC
TTCATTTGGCGACTCTAGTGCTTTAAAAGTTGGTGAACCTGCAATTGCAATTGGTTCTCCTTTAGGTTCCGAATATGCCA
ATTCAGTGACGTCAGGTATAGTTTCTTCTTTGAACCGACAAGTGACAAGTACAAATGAATCCAACGAAACTGTAAATATC
AATGCGATCCAAACAGATGCTGCAATCAATCCTGGTAACTCAGGTGGTCCACTGATCAACATTGAAGGACAAGTGATTGG
GATCAACTCAAGTAAAATCGCTACTACTTCTGAATCTTCATCTGGCGTAAGTGTTGAAGGTATGGGCTTTGCAATCCCAA
GTAATGATGTAGTCAATATCATCAACCAACTTGAAAAAGATGGTAAAGTGACACGTCCTGCATTAGGAATTACGATGTAC
GATTTATCTTATGTTTCAACGCAGCAAAAAGAACAAGTCTTGAAGATTCCTTCTTCAGTCACAAATGGTGTGATCGTGGC
AAGTGTCCAACCAGCAACACCTGCTGAAAAAGCTGGTTTGAAACAATATGATGTAATTACTAAAATCGACGACACGGAAG
TTTCATCTGGTGTTGAGTTACAATCAGCTCTTTATAAGAAAAAAGTTGGTGACACAGTAAAAATCACTTATTACCAAGAA
AAAGATGAAAAAACTGCTACAGTTGAATTGACGATCGATCAATCTGCATTAAAACAAAACCAATCATCGAATTCAGGAAA
CTGA

Domains

Predicted by InterproScan.

Peptidase family M50 (Peptidase_M50)

(8-419)

PDZ domain (PDZ_2)

(313-410)

Trypsin-like peptidase domain (Trypsin_2)

(123-268)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A367CHU7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus gordonii str. Challis substr. CH1

53.333

94.848

0.506
  htrA Streptococcus mitis NCTC 12261

54.522

90.632

0.494
  htrA Streptococcus mutans UA159

58.611

84.309

0.494
  htrA Streptococcus pneumoniae TIGR4

59.763

79.157

0.473
  htrA Streptococcus pneumoniae R6

59.763

79.157

0.473
  htrA Streptococcus pneumoniae Rx1

59.763

79.157

0.473
  htrA Streptococcus pneumoniae D39

59.763

79.157

0.473

Multiple sequence alignment