Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC/celB   Type   Machinery gene
Locus tag   CHF41_RS05065 Genome accession   NZ_CP022680
Coordinates   997323..999665 (+) Length   780 a.a.
NCBI ID   WP_119876270.1    Uniprot ID   -
Organism   Streptococcus respiraculi strain HTS25     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 981568..999665 997323..999665 within 0


Gene organization within MGE regions


Location: 981568..999665
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CHF41_RS04995 - 981568..981870 (+) 303 WP_119876259.1 hypothetical protein -
  CHF41_RS05000 - 982038..986360 (+) 4323 WP_119876260.1 SpaA isopeptide-forming pilin-related protein -
  CHF41_RS05005 - 986587..986796 (+) 210 WP_240622969.1 PC4/YdbC family ssDNA-binding protein -
  CHF41_RS05010 - 986786..987007 (+) 222 WP_228065155.1 hypothetical protein -
  CHF41_RS05015 - 987023..987772 (+) 750 WP_119876262.1 hypothetical protein -
  CHF41_RS05020 - 987774..988136 (+) 363 WP_119876263.1 PrgI family protein -
  CHF41_RS05025 - 988090..990462 (+) 2373 WP_119876264.1 VirB4-like conjugal transfer ATPase, CD1110 family -
  CHF41_RS05030 - 990482..993076 (+) 2595 WP_119876265.1 phage tail tip lysozyme -
  CHF41_RS05035 - 993099..993713 (+) 615 WP_119876266.1 hypothetical protein -
  CHF41_RS05040 - 993989..994954 (-) 966 WP_119876267.1 DDE-type integrase/transposase/recombinase -
  CHF41_RS05050 - 995385..996254 (+) 870 WP_240622970.1 minor capsid protein -
  CHF41_RS05055 - 996217..996426 (+) 210 WP_119876268.1 CPCC family cysteine-rich protein -
  CHF41_RS05060 comEA 996701..997339 (+) 639 WP_119876269.1 helix-hairpin-helix domain-containing protein Machinery gene
  CHF41_RS05065 comEC/celB 997323..999665 (+) 2343 WP_119876270.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene

Sequence

Protein


Download         Length: 780 a.a.        Molecular weight: 89127.40 Da        Isoelectric Point: 8.4040

>NTDB_id=241577 CHF41_RS05065 WP_119876270.1 997323..999665(+) (comEC/celB) [Streptococcus respiraculi strain HTS25]
MSQLIKKLPLAPIHLIVLLLALYFVMYRLSVLSGLILVGLLILLWVRQGKKVCYQILPILACFFLFFGFQCVKSTLDESA
TPTEVSSLTVKPDSIQVNGDSLSFRATSSGHLYTVFYQLKSQEEQRYFKSLSSLARLEVEATVSEPEGQRNFNGFDYRDY
LRTHGIYKTIKISKIEKIEKRVAWNPLDWLFLVRRKALVYIKEHFPSPMRHYMTGLLFGDLDKEFDQMSDLYSSLGIIHL
FALSGMQVGFFVDKFRSLFLRLGIRKEVVDWLQVPFSFIYAGLTGFSVSVTRSLVQKIFANMGITKLDNIACTMMISFLL
MPHFLLTADGVLSFSYAFLLTVFDFEDFVSYKRVVVESVAISLGIFPLLIYYFYSFQPLSILLTFLFSFLFDMVLLPGLS
LIFLLSPLVKITPVNFLFVWLESSIQWVAGLGLKPWIFGKPTAVCLLVLLGVLLLVYDLYQNPKCCIALLSLAALLFFIT
KHPLENEVTVVDVGQGDSIFLRDMRGRTVLIDVGGKVSVGSKEPWQEQSSQVNAERTLIPYLHSRGVSKIDYLVLTHAHA
DHMGDLMEMAREMDIGSIYISEGSTTSKELIKMLQTIKTPPHLVKVGDAIPICDGFLRVLYPYQKGNGGNNDSVVLYGEL
LQTRFLFTGDLEDGELELIKRYPRLSVDVLKAGHHGSRGSSYPEFLDAISPRIALISAGKHNRYQHPHQEALQRFQERQM
QVFRTDEQGAIRFRGWKMWQIETVKSVERDMLFSFVEEFSKWYNGRSYVWFFTNLERLGM

Nucleotide


Download         Length: 2343 bp        

>NTDB_id=241577 CHF41_RS05065 WP_119876270.1 997323..999665(+) (comEC/celB) [Streptococcus respiraculi strain HTS25]
ATGTCACAGTTGATTAAAAAGCTTCCTCTTGCTCCTATTCATCTAATCGTTTTACTACTAGCCCTCTATTTTGTCATGTA
CCGCCTATCTGTCTTATCAGGTCTGATTTTGGTGGGCTTATTGATTCTGCTCTGGGTTCGTCAAGGGAAAAAAGTTTGCT
ATCAAATTTTACCGATTTTAGCTTGCTTTTTCCTTTTCTTTGGCTTCCAATGTGTAAAGTCTACTCTGGACGAGTCTGCT
ACTCCGACGGAGGTCAGTTCGTTGACTGTTAAGCCAGACAGCATTCAAGTCAATGGTGATAGTCTTTCTTTTCGGGCGAC
ATCATCAGGGCATCTGTACACTGTTTTTTACCAATTGAAAAGTCAAGAAGAGCAGCGTTATTTTAAAAGTTTATCCAGTC
TAGCCAGATTGGAGGTGGAAGCAACGGTGTCTGAGCCAGAGGGACAACGGAATTTCAATGGCTTTGATTATCGGGATTAT
TTGAGAACTCATGGGATTTATAAGACGATCAAGATTAGCAAGATTGAGAAGATAGAAAAGCGGGTAGCTTGGAATCCTTT
GGACTGGCTTTTTCTCGTTCGACGCAAGGCTTTGGTCTACATCAAGGAGCATTTTCCAAGTCCGATGCGGCATTATATGA
CAGGACTCTTGTTTGGTGACTTGGACAAGGAATTTGACCAGATGAGCGACCTTTACTCTAGCTTAGGGATTATCCATTTA
TTTGCGCTTTCGGGGATGCAGGTCGGTTTTTTTGTAGATAAGTTCCGTTCTCTTTTCTTGCGCCTTGGGATTCGAAAGGA
AGTTGTCGATTGGCTCCAAGTTCCCTTTTCTTTTATTTATGCGGGTTTGACAGGTTTTTCCGTCTCAGTCACTCGTTCTC
TCGTACAAAAGATCTTTGCTAATATGGGCATCACTAAGCTGGATAATATAGCTTGTACGATGATGATTTCTTTTCTACTC
ATGCCTCATTTTTTATTAACAGCAGATGGTGTGTTGAGCTTTTCCTATGCCTTTTTACTGACTGTTTTTGATTTCGAAGA
TTTTGTATCGTATAAACGGGTAGTTGTAGAAAGTGTAGCGATTTCACTCGGGATTTTCCCCCTCTTAATTTACTATTTTT
ATAGTTTTCAACCCTTGTCGATTCTCTTGACCTTCCTCTTTTCCTTTCTTTTTGATATGGTCTTGTTACCGGGGTTAAGT
CTTATCTTTCTTCTTTCTCCACTCGTCAAAATCACGCCGGTCAATTTTCTTTTTGTCTGGCTAGAATCCTCTATTCAGTG
GGTAGCAGGTCTGGGCTTGAAACCATGGATTTTTGGCAAGCCAACAGCTGTTTGCCTCTTGGTCTTGTTGGGCGTTTTGC
TCTTAGTGTACGATCTGTATCAGAATCCTAAATGCTGCATAGCCCTCCTTAGCCTAGCTGCTCTGCTATTTTTTATCACC
AAACACCCTTTGGAAAACGAGGTGACAGTAGTGGATGTTGGTCAGGGAGATAGCATCTTTTTGCGAGATATGCGAGGGCG
GACGGTGCTGATTGATGTGGGTGGCAAAGTGAGTGTTGGATCAAAAGAGCCTTGGCAAGAACAATCTAGTCAGGTGAATG
CGGAGCGAACCTTGATTCCCTATCTTCATAGTCGTGGTGTGAGTAAGATTGATTATTTGGTCTTGACTCATGCACATGCG
GACCATATGGGGGATTTAATGGAGATGGCTAGAGAAATGGATATTGGCAGTATCTACATTTCTGAGGGGAGCACAACTAG
CAAAGAGCTGATAAAGATGTTACAGACAATAAAGACACCGCCTCACCTAGTAAAAGTAGGAGACGCTATTCCGATATGCG
ACGGCTTTTTACGTGTGCTCTATCCTTATCAAAAGGGGAATGGTGGCAATAATGACTCGGTGGTGTTATACGGTGAGCTA
TTGCAGACCCGTTTTCTATTTACAGGGGATTTGGAAGACGGTGAATTGGAGTTGATTAAGCGATATCCTCGCTTGTCTGT
TGATGTTTTAAAGGCAGGACATCATGGTTCAAGAGGCTCTTCTTATCCAGAATTTTTGGATGCTATTTCTCCAAGGATAG
CCCTGATTTCAGCGGGAAAACACAATCGTTACCAGCATCCGCATCAGGAAGCTCTTCAACGATTTCAAGAGCGGCAGATG
CAGGTATTTCGGACGGATGAACAAGGTGCTATTCGTTTCCGAGGCTGGAAGATGTGGCAGATTGAGACGGTGAAATCGGT
GGAAAGGGATATGCTATTCTCATTTGTGGAAGAGTTTTCGAAGTGGTATAATGGTAGAAGTTATGTTTGGTTTTTCACAA
ACTTAGAAAGGTTAGGAATGTAA

Domains

Predicted by InterproScan.

Competence protein (Competence)

(216-458)

Metallo-beta-lactamase superfamily (Lactamase_B)

(492-699)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC/celB Streptococcus mitis SK321

51.272

95.769

0.491
  comEC/celB Streptococcus mitis NCTC 12261

50.536

95.641

0.483
  comEC/celB Streptococcus pneumoniae TIGR4

50.067

95.769

0.479
  comEC/celB Streptococcus pneumoniae Rx1

49.398

95.769

0.473
  comEC/celB Streptococcus pneumoniae D39

49.398

95.769

0.473
  comEC/celB Streptococcus pneumoniae R6

49.398

95.769

0.473
  comEC Lactococcus lactis subsp. cremoris KW2

44.933

96.154

0.432

Multiple sequence alignment