Detailed information NTG0241080

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: Sp14A_RS11445
• Genome accession: NZ_CP022601
• Coordinates: 2244018..2245166 (+)
• Length: 382 a.a.
• NCBI ID: WP_115131126.1
• Uniprot ID: -
• Organism: Streptococcus pluranimalium strain 14A0014
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2239018..2250166

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Sp14A_RS11420 (Sp14A_23590)	-	2240149..2241351 (+)	1203	WP_115129493.1	IS110 family transposase	-
Sp14A_RS11425 (Sp14A_23600)	-	2241587..2242843 (+)	1257	WP_115130315.1	ISL3 family transposase	-
Sp14A_RS11440 (Sp14A_23630)	rlmH	2243238..2243717 (-)	480	WP_115131125.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
Sp14A_RS11445 (Sp14A_23640)	htrA	2244018..2245166 (+)	1149	WP_115131126.1	trypsin-like peptidase domain-containing protein	Regulator
Sp14A_RS11450 (Sp14A_23650)	spo0J	2245220..2245987 (+)	768	WP_115131127.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 382 a.a.
• Molecular weight: 40491.01 Da
• Isoelectric Point: 4.3484

>NTDB_id=241080 Sp14A_RS11445 WP_115131126.1 2244018..2245166(+) (htrA) [Streptococcus pluranimalium strain 14A0014]
MAGAYLMLYFSNNLSTPLNNSQSKAKTSNVVYNNTTNTTKAAKKVQDAVVSVINYQKNTDSSLNDLYSQMFGGGDDKRSE
DDLSVYSEGSGVIYRKEGGSAYIVTNNHVIDGAENIEIMLADGTKVVGELVGSDTYSDLAVVKISDEKVSTVAEFADSDK
LNVGEVAIAMGSPLGSEYANSVTQGIVSSLSRTVTLKNEEGETISTNAIQTDAAINPGNSGGALINIEGQVIGINSSKIS
STSTAREAVEGMGFAIPSNDVIKIINQLEKNGQVTRPALGISMANLSDLSTSAISELNIPNKLTGGIVVATVQDKMPASG
KLKQYDVITEIDGEEITSTSDLQSILYGHEIGDTIKITYYRGKDKQTTDIKLSKSTQDLENS

Nucleotide

• Length: 1149 bp

>NTDB_id=241080 Sp14A_RS11445 WP_115131126.1 2244018..2245166(+) (htrA) [Streptococcus pluranimalium strain 14A0014]
ATGGCAGGAGCTTATCTCATGCTCTATTTTTCCAATAACCTGTCAACTCCTTTGAATAATTCGCAATCCAAAGCCAAAAC
AAGCAATGTGGTTTACAATAATACTACCAACACGACTAAAGCAGCCAAAAAAGTCCAAGATGCTGTTGTATCAGTTATTA
ACTACCAAAAGAATACCGATTCTTCTTTAAATGATCTTTATAGTCAAATGTTTGGTGGAGGCGATGATAAGCGTTCTGAA
GATGATTTGAGTGTCTACAGCGAAGGCTCTGGCGTTATTTATCGAAAAGAAGGTGGATCAGCTTATATCGTCACTAACAA
TCACGTTATTGATGGAGCTGAAAATATCGAAATTATGCTTGCTGATGGAACAAAAGTCGTCGGAGAACTTGTTGGATCTG
ATACTTACTCCGATTTAGCTGTTGTCAAAATTTCTGATGAAAAAGTATCTACAGTTGCGGAGTTCGCAGACTCTGATAAA
TTAAACGTTGGAGAAGTAGCGATTGCAATGGGTAGCCCTCTAGGAAGTGAATATGCTAACTCTGTTACACAAGGAATTGT
GTCAAGTCTAAGCCGTACAGTAACGCTTAAAAATGAGGAGGGGGAAACCATTTCAACCAATGCTATCCAAACAGATGCTG
CCATCAACCCTGGTAACTCTGGTGGTGCTTTGATTAATATTGAAGGACAAGTTATTGGTATCAATTCAAGTAAAATCTCA
TCTACCTCAACTGCTCGCGAAGCCGTAGAAGGCATGGGATTTGCTATCCCATCTAATGATGTCATCAAAATTATCAATCA
GTTAGAAAAAAATGGACAAGTAACTCGCCCAGCACTAGGCATCTCTATGGCGAATCTTAGCGATCTCTCAACAAGTGCTA
TCTCAGAACTGAATATCCCAAATAAGCTTACTGGAGGTATTGTTGTTGCCACTGTGCAAGATAAAATGCCTGCCTCAGGT
AAACTGAAACAATATGATGTCATCACTGAAATTGATGGTGAAGAAATAACATCAACCAGTGATCTACAAAGTATTCTTTA
TGGTCACGAAATTGGTGATACGATAAAAATCACCTACTACCGTGGTAAAGATAAGCAGACCACTGACATTAAGTTAAGCA
AGTCAACACAAGATTTAGAAAACAGCTAA

Domains

Predicted by InterproScan.

• Trypsin-like peptidase domain (Trypsin_2) (89-234)

• PDZ domain (PDZ_2) (277-372)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	67.112	97.906	0.657
htrA	Streptococcus mitis NCTC 12261	63.897	91.361	0.584
htrA	Streptococcus gordonii str. Challis substr. CH1	58.575	99.215	0.581
htrA	Streptococcus pneumoniae TIGR4	63.61	91.361	0.581
htrA	Streptococcus pneumoniae R6	63.61	91.361	0.581
htrA	Streptococcus pneumoniae Rx1	63.61	91.361	0.581
htrA	Streptococcus pneumoniae D39	63.61	91.361	0.581