Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   Sp14A_RS07900 Genome accession   NZ_CP022601
Coordinates   1549803..1550510 (-) Length   235 a.a.
NCBI ID   WP_104968255.1    Uniprot ID   A0A2L0D523
Organism   Streptococcus pluranimalium strain 14A0014     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1544803..1555510
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Sp14A_RS07885 (Sp14A_16350) rnc 1546718..1547419 (-) 702 WP_115130593.1 ribonuclease III -
  Sp14A_RS07890 (Sp14A_16360) vicX 1547653..1548462 (-) 810 WP_115130594.1 MBL fold metallo-hydrolase Regulator
  Sp14A_RS07895 (Sp14A_16370) vicK 1548464..1549810 (-) 1347 WP_104968254.1 cell wall metabolism sensor histidine kinase VicK Regulator
  Sp14A_RS07900 (Sp14A_16380) vicR 1549803..1550510 (-) 708 WP_104968255.1 response regulator YycF Regulator
  Sp14A_RS07905 (Sp14A_16390) - 1550750..1551535 (+) 786 WP_115130595.1 amino acid ABC transporter ATP-binding protein -
  Sp14A_RS07910 (Sp14A_16400) - 1551546..1552373 (+) 828 WP_115130596.1 transporter substrate-binding domain-containing protein -
  Sp14A_RS07915 (Sp14A_16410) - 1552392..1553087 (+) 696 WP_115130597.1 amino acid ABC transporter permease -
  Sp14A_RS07920 (Sp14A_16420) - 1553096..1553746 (+) 651 WP_104968259.1 amino acid ABC transporter permease -
  Sp14A_RS07925 (Sp14A_16430) - 1553832..1554431 (-) 600 WP_115130598.1 response regulator transcription factor -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 26945.82 Da        Isoelectric Point: 4.7489

>NTDB_id=241064 Sp14A_RS07900 WP_104968255.1 1549803..1550510(-) (vicR) [Streptococcus pluranimalium strain 14A0014]
MKTILVVDDERPISDIIKFNLSKEGYTIETAFDGHDAVEKFEDIKPDLVILDLMLPGMDGLEVAKEIRKTSHTPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAQLRRVETIETVAEESLQSSPTEIEIGNLQILPEAFIAKKNGEEVEL
THREFELLYHLAQHIGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIETTPSRPEYILTRRGVGYFMKAHD

Nucleotide


Download         Length: 708 bp        

>NTDB_id=241064 Sp14A_RS07900 WP_104968255.1 1549803..1550510(-) (vicR) [Streptococcus pluranimalium strain 14A0014]
ATGAAAACAATTCTCGTTGTAGATGATGAAAGACCCATCTCAGACATTATAAAATTTAATCTGAGTAAGGAAGGCTATAC
TATTGAAACAGCCTTTGATGGTCATGACGCGGTTGAAAAATTTGAAGATATTAAGCCTGACTTGGTTATTTTGGACTTGA
TGTTGCCAGGAATGGATGGTCTTGAGGTAGCTAAAGAAATCCGTAAAACAAGTCACACGCCAATTATTATGTTATCGGCT
AAGGATTCTGAGTTCGATAAGGTGATTGGCTTGGAAATCGGTGCAGATGATTATGTCACAAAACCCTTCTCTAATCGAGA
GTTATTGGCGCGTGTGAAAGCTCAACTACGTCGTGTTGAGACCATTGAAACTGTGGCAGAAGAATCTCTTCAATCCTCTC
CGACAGAAATCGAGATTGGGAACCTTCAAATCTTACCAGAGGCGTTTATTGCTAAAAAGAACGGAGAGGAAGTCGAGCTG
ACGCATCGTGAGTTTGAATTGCTCTATCATTTGGCGCAACATATTGGTCAAGTGATGACACGCGAGCATCTCCTTGAAAC
GGTTTGGGGATATGACTATTTTGGTGATGTTCGGACAGTTGATGTGACTATTCGTCGCCTCCGTGAAAAAATCGAGACAA
CTCCAAGTCGTCCGGAATACATTCTCACTCGTCGTGGAGTGGGATACTTTATGAAAGCTCATGACTGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-230)

Response regulator receiver domain (Response_reg)

(4-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

79.574

100

0.796
  micA Streptococcus pneumoniae Cp1015

73.932

99.574

0.736
  covR Lactococcus lactis subsp. lactis strain DGCC12653

43.29

98.298

0.426
  covR Streptococcus salivarius strain HSISS4

41.126

98.298

0.404
  scnR Streptococcus mutans UA159

36.864

100

0.37

Multiple sequence alignment