Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   Sp14A_RS07895 Genome accession   NZ_CP022601
Coordinates   1548464..1549810 (-) Length   448 a.a.
NCBI ID   WP_104968254.1    Uniprot ID   A0A2L0D530
Organism   Streptococcus pluranimalium strain 14A0014     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1543464..1554810
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Sp14A_RS07885 (Sp14A_16350) rnc 1546718..1547419 (-) 702 WP_115130593.1 ribonuclease III -
  Sp14A_RS07890 (Sp14A_16360) vicX 1547653..1548462 (-) 810 WP_115130594.1 MBL fold metallo-hydrolase Regulator
  Sp14A_RS07895 (Sp14A_16370) vicK 1548464..1549810 (-) 1347 WP_104968254.1 cell wall metabolism sensor histidine kinase VicK Regulator
  Sp14A_RS07900 (Sp14A_16380) vicR 1549803..1550510 (-) 708 WP_104968255.1 response regulator YycF Regulator
  Sp14A_RS07905 (Sp14A_16390) - 1550750..1551535 (+) 786 WP_115130595.1 amino acid ABC transporter ATP-binding protein -
  Sp14A_RS07910 (Sp14A_16400) - 1551546..1552373 (+) 828 WP_115130596.1 transporter substrate-binding domain-containing protein -
  Sp14A_RS07915 (Sp14A_16410) - 1552392..1553087 (+) 696 WP_115130597.1 amino acid ABC transporter permease -
  Sp14A_RS07920 (Sp14A_16420) - 1553096..1553746 (+) 651 WP_104968259.1 amino acid ABC transporter permease -
  Sp14A_RS07925 (Sp14A_16430) - 1553832..1554431 (-) 600 WP_115130598.1 response regulator transcription factor -

Sequence

Protein


Download         Length: 448 a.a.        Molecular weight: 51137.14 Da        Isoelectric Point: 4.7338

>NTDB_id=241063 Sp14A_RS07895 WP_104968254.1 1548464..1549810(-) (vicK) [Streptococcus pluranimalium strain 14A0014]
MTDQFLFSFRDVIIAGLMSILVLIYVFLIIRDTLNSRRVQQLTEQVQALISGEYVVNQVTRGSAEVKDLAEHLNDLSEVF
RLTHENLGQEKNRLSSILSYMSDGVLATDRRGNIIMINDMARQQLNLSEEGDLAINIMTLLEDTSYTYHDLITKTPEVTL
HRVDEFGEFTVLRVNFALIKRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALKEAV
APGFIRVSLDETNRMMRMITDLLSLSRIDNNNSELEVELTNFTAFITYILNRFDRIKLQETHAGKSYDIKRNYDLTPVWI
EIDNDKMTQVFDNILNNAIKYSPDGGEIKVSMRTTDTQLIVSVSDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTGLGL
AITKEIVKQHNGFIWAKSDYGKGSTFTIVLPYEKNILEVDEEWEVTED

Nucleotide


Download         Length: 1347 bp        

>NTDB_id=241063 Sp14A_RS07895 WP_104968254.1 1548464..1549810(-) (vicK) [Streptococcus pluranimalium strain 14A0014]
ATGACTGATCAATTTCTTTTTTCATTTCGAGATGTTATTATTGCAGGGCTAATGTCAATTTTAGTCCTGATTTATGTTTT
TTTAATTATTCGAGATACTTTAAATAGTCGACGTGTGCAACAATTGACGGAGCAAGTTCAAGCCTTGATTTCAGGTGAGT
ATGTGGTCAATCAGGTAACACGAGGAAGTGCTGAAGTTAAGGACTTAGCTGAACATTTGAACGATCTATCTGAGGTTTTT
CGTCTAACACATGAAAATTTAGGACAAGAAAAAAATCGTCTTTCAAGTATTTTATCCTATATGAGCGATGGGGTTTTAGC
AACAGACCGTCGTGGTAATATCATTATGATTAATGATATGGCAAGGCAACAGTTGAACTTATCAGAAGAAGGTGACCTTG
CCATCAATATTATGACTTTGTTAGAAGATACCTCGTATACTTATCATGATTTAATAACCAAAACACCCGAAGTAACGCTT
CACCGTGTCGATGAGTTTGGTGAATTTACGGTACTGAGGGTCAATTTTGCTCTTATCAAGAGAGAGAGTGGTTTTATATC
TGGTTTGGTAGCCGTTTTACACGATACAACAGAACAAGAAAAAGAGGAACGTGAACGTCGTCTCTTTGTTTCCAATGTTA
GTCATGAATTACGGACTCCTCTAACATCGGTAAAGTCGTATCTTGAAGCCTTGGATGAAGGCGCCCTTAAGGAAGCTGTT
GCCCCTGGGTTTATCCGTGTTTCCCTAGATGAAACAAACCGGATGATGCGGATGATTACAGACTTGCTATCCCTATCACG
TATTGATAATAATAATAGTGAATTAGAAGTTGAACTGACGAACTTTACAGCTTTTATCACCTATATCCTAAATCGCTTTG
ACCGGATCAAGTTACAGGAAACACATGCAGGAAAATCTTATGATATTAAGCGCAACTACGATCTGACTCCTGTTTGGATT
GAGATTGATAATGATAAGATGACCCAAGTTTTCGATAATATTTTAAACAATGCGATCAAGTATTCACCAGATGGTGGTGA
GATTAAGGTGAGCATGCGAACGACTGATACTCAATTAATTGTATCGGTATCTGACCAAGGATTGGGAATTCCTAAAAAAG
ACTTGCCTTTAATTTTTGACCGTTTCTACCGTGTTGATAAGGCAAGAAGCCGTGCCCAAGGAGGCACTGGACTCGGTCTA
GCAATTACCAAAGAAATTGTTAAACAACACAATGGCTTTATTTGGGCTAAAAGTGATTACGGTAAGGGATCAACGTTTAC
CATCGTTTTACCGTATGAAAAGAATATTTTAGAAGTAGACGAAGAATGGGAGGTAACTGAAGACTAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(206-270)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(323-433)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2L0D530

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

71.29

91.741

0.654
  micB Streptococcus pneumoniae Cp1015

64.896

96.652

0.627

Multiple sequence alignment