Detailed information NTG0241061

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: Sp14A_RS07790
• Genome accession: NZ_CP022601
• Coordinates: 1525198..1527348 (+)
• Length: 716 a.a.
• NCBI ID: WP_115130577.1
• Uniprot ID: A0A345VLC5
• Organism: Streptococcus pluranimalium strain 14A0014
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 1520198..1532348

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Sp14A_RS07765 (Sp14A_16120)	-	1520482..1521606 (-)	1125	WP_115130575.1	glycosyltransferase family 2 protein	-
Sp14A_RS07770	-	1521949..1522195 (+)	247	Protein_1494	IS110 family transposase	-
Sp14A_RS07775 (Sp14A_16140)	traF	1522486..1523673 (-)	1188	WP_115130576.1	conjugal transfer protein TraF	-
Sp14A_RS11495	-	1523691..1523858 (-)	168	WP_162797778.1	hypothetical protein	-
Sp14A_RS07780 (Sp14A_16150)	-	1524229..1524540 (-)	312	WP_240314746.1	bacteriocin immunity protein	-
Sp14A_RS07785	-	1524674..1524904 (-)	231	Protein_1498	leucocin A/sakacin P family class II bacteriocin	-
Sp14A_RS07790 (Sp14A_16170)	comA/nlmT	1525198..1527348 (+)	2151	WP_115130577.1	peptide cleavage/export ABC transporter	Regulator
Sp14A_RS07795 (Sp14A_16180)	-	1527358..1528683 (+)	1326	WP_115130578.1	bacteriocin secretion accessory protein	-
Sp14A_RS07800 (Sp14A_16190)	-	1528832..1528969 (+)	138	WP_115130579.1	bacteriocin	-
Sp14A_RS07805 (Sp14A_16200)	-	1529050..1530369 (-)	1320	WP_115130580.1	GHKL domain-containing protein	-
Sp14A_RS07810 (Sp14A_16210)	-	1530366..1531109 (-)	744	WP_115130581.1	LytTR family DNA-binding domain-containing protein	-
Sp14A_RS11500	-	1531564..1531788 (+)	225	WP_162797779.1	hypothetical protein	-

Sequence

Protein

• Length: 716 a.a.
• Molecular weight: 79920.84 Da
• Isoelectric Point: 7.1132

>NTDB_id=241061 Sp14A_RS07790 WP_115130577.1 1525198..1527348(+) (comA/nlmT) [Streptococcus pluranimalium strain 14A0014]
MSRYKRTFIPQVDARDCGVAALASIAAFYGSRYSLAHLRELAKTNKEGTTALGLVKAAQEIDFETRAIQADASLFEMDDV
PYPFIAHVNKEGKLQHYYVVYQAGKKGLVIGDPDPSVKVTKMSYDTFLSEWTGVALFMGPKPSYKPHKDKKNGLTSFLPL
IFKQKAVISQIVIASLLVTIINIVGSYYLQSILDDYIPNHMLSTLGIISVGLIVTYVIQQVMTFARDYLLTVLSQRLTID
VILSYIKHIFDLPMSFFATRRTGEITSRFTDATAIIDALASTILSLFLDVSIVVIVGGVLLLQNPHLFFLSLVSIPVYLV
IIFAFMKPFERMNNDVMQSNAMVSSAIIEDINGIETIKSLTSEEVRYQKIDREFVDYLDKSFILSKLSILQSALKQGAQL
ILNVLILWLGSRLVIQGKISVGQLITFNTLLSYFTDPLENIINLQTKLQSAKVANTRLNEVYLVDSEFKDNTFETDATML
NGDIIFDHVSYKFGFGRDTLSDISLTINEKTKVALVGISGSGKTTLAKMIVNFYEPYQGTIRVNGNDLKTLNKKVLRRHI
NYLPQQAYIFDGSILDNLTLGVQEGISQEDIIRACEIAEIRQDIEQMPMGYQTELSDGAGLSGGQKQRIALARALLTKAP
VLILDEATSGLDVLTEKKVIDNLLALDKTIIFVAHRLSIAQRAEKILVLDQGKLVEEGSHSDLVRRQGFYYHLFSK

Nucleotide

• Length: 2151 bp

>NTDB_id=241061 Sp14A_RS07790 WP_115130577.1 1525198..1527348(+) (comA/nlmT) [Streptococcus pluranimalium strain 14A0014]
ATGTCAAGATACAAACGAACCTTTATCCCTCAGGTTGATGCTAGGGATTGTGGGGTGGCAGCTTTGGCTTCTATTGCTGC
TTTTTATGGGTCTAGGTACTCACTCGCTCACTTAAGAGAACTCGCTAAAACCAATAAGGAGGGCACCACCGCTCTTGGAT
TAGTCAAGGCTGCTCAAGAAATCGACTTTGAAACAAGAGCCATCCAAGCGGATGCTAGTCTCTTTGAAATGGATGATGTT
CCCTATCCTTTCATCGCCCATGTCAATAAGGAAGGAAAACTACAACACTACTATGTTGTCTATCAGGCTGGCAAGAAAGG
GCTAGTCATTGGTGATCCTGATCCTAGTGTCAAAGTCACTAAAATGTCCTACGATACCTTCCTTTCTGAATGGACTGGTG
TTGCCTTATTTATGGGACCTAAACCATCCTACAAGCCCCATAAGGATAAAAAGAATGGCTTGACCAGTTTTCTGCCCCTC
ATTTTTAAGCAGAAAGCTGTTATTAGTCAGATTGTCATTGCTAGCCTCCTTGTGACCATCATTAACATTGTTGGTTCTTA
TTATCTACAATCCATTTTAGATGATTATATTCCCAATCATATGCTCTCCACCCTTGGGATTATTTCTGTTGGCTTGATTG
TGACTTATGTTATCCAACAAGTGATGACCTTTGCCAGGGATTATCTGCTTACTGTGCTTAGTCAGCGCTTGACCATTGAT
GTTATTTTATCTTATATCAAGCACATTTTTGACCTTCCCATGTCTTTTTTTGCGACTAGACGTACTGGTGAAATCACCTC
ACGCTTTACAGATGCCACTGCTATCATTGATGCTCTAGCGTCCACTATCCTATCTCTTTTTCTAGACGTCTCAATCGTTG
TCATTGTCGGTGGGGTCTTGTTACTGCAAAACCCTCATCTTTTCTTCCTGTCACTGGTTTCTATTCCAGTCTATCTTGTC
ATTATTTTTGCCTTTATGAAACCTTTTGAACGGATGAATAACGATGTGATGCAAAGTAATGCCATGGTCAGTTCAGCCAT
TATTGAGGATATCAACGGGATTGAGACGATTAAATCATTAACCAGTGAGGAAGTGCGTTACCAAAAGATTGACCGTGAGT
TTGTGGATTATCTCGATAAATCTTTCATTTTAAGCAAACTGTCTATTCTTCAGTCCGCTTTGAAGCAAGGCGCTCAACTC
ATTCTCAACGTCCTCATCCTTTGGTTAGGGTCAAGACTTGTGATTCAAGGAAAAATCTCCGTTGGTCAACTCATTACTTT
TAACACCTTGTTAAGCTATTTTACGGATCCTTTAGAAAACATCATTAACCTCCAAACCAAGTTACAATCTGCAAAAGTTG
CCAATACCCGCCTCAATGAAGTTTACCTAGTTGATTCTGAATTTAAAGACAACACCTTTGAAACGGATGCTACGATGCTT
AATGGCGATATCATTTTTGATCACGTTTCTTATAAATTTGGTTTTGGACGCGATACCTTATCTGATATTTCCCTTACCAT
CAACGAAAAAACAAAAGTTGCTCTGGTGGGCATTAGTGGTTCTGGTAAAACAACTCTCGCTAAAATGATTGTCAATTTTT
ATGAGCCTTATCAGGGAACGATTCGAGTGAATGGTAACGATCTTAAAACACTCAATAAGAAAGTGCTACGCCGCCATATT
AATTATCTACCCCAGCAGGCTTATATTTTTGATGGCTCTATCCTTGATAATCTGACCTTAGGAGTTCAAGAAGGGATTAG
CCAAGAAGACATTATAAGAGCTTGTGAGATTGCCGAAATTCGTCAGGATATTGAACAAATGCCTATGGGCTATCAAACGG
AGTTATCAGATGGCGCAGGCTTATCAGGAGGGCAGAAACAACGCATTGCCCTAGCACGTGCCTTACTCACAAAGGCACCA
GTCCTCATTCTCGACGAAGCAACAAGTGGCTTGGATGTTCTCACAGAGAAAAAAGTCATTGACAACCTCTTAGCCCTTGA
TAAAACCATTATCTTTGTGGCGCACCGTCTCAGCATTGCTCAACGAGCTGAGAAAATCCTTGTCTTAGACCAAGGCAAAC
TTGTCGAAGAAGGCTCCCATAGCGATTTGGTGAGACGCCAAGGCTTTTATTATCATTTGTTTAGTAAATAA

Domains

Predicted by InterproScan.

• ABC transporter transmembrane region (ABC_membrane) (171-438)

• ABC transporter (ABC_tran) (500-649)

• Peptidase C39 family (Peptidase_C39) (7-142)

3D structure

• AlphaFold DB: A0A345VLC5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	70.308	99.721	0.701
comA	Streptococcus mitis NCTC 12261	67.606	99.162	0.67
comA	Streptococcus mitis SK321	67.042	99.162	0.665
comA	Streptococcus pneumoniae Rx1	67.042	99.162	0.665
comA	Streptococcus pneumoniae D39	67.042	99.162	0.665
comA	Streptococcus pneumoniae R6	67.042	99.162	0.665
comA	Streptococcus pneumoniae TIGR4	66.761	99.162	0.662
comA	Streptococcus gordonii str. Challis substr. CH1	65.266	99.721	0.651