Detailed information NTG0241053

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: Sp14A_RS05530
• Genome accession: NZ_CP022601
• Coordinates: 1042705..1043547 (+)
• Length: 280 a.a.
• NCBI ID: WP_104967818.1
• Uniprot ID: A0A2L0D4I4
• Organism: Streptococcus pluranimalium strain 14A0014
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1037705..1048547

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Sp14A_RS05500 (Sp14A_11500)	-	1037914..1038147 (+)	234	WP_115130235.1	DNA-binding protein	-
Sp14A_RS05505 (Sp14A_11510)	-	1038222..1039730 (+)	1509	WP_115130236.1	tyrosine-type recombinase/integrase	-
Sp14A_RS05510 (Sp14A_11520)	ylqF	1039821..1040672 (+)	852	WP_115130237.1	ribosome biogenesis GTPase YlqF	-
Sp14A_RS05515 (Sp14A_11530)	-	1040659..1041444 (+)	786	WP_115130238.1	ribonuclease HII	-
Sp14A_RS05520 (Sp14A_11540)	-	1041440..1042090 (+)	651	WP_104968841.1	GNAT family N-acetyltransferase	-
Sp14A_RS05525 (Sp14A_11550)	-	1042087..1042635 (+)	549	WP_115130239.1	sugar O-acetyltransferase	-
Sp14A_RS05530 (Sp14A_11560)	dprA	1042705..1043547 (+)	843	WP_104967818.1	DNA-processing protein DprA	Machinery gene
Sp14A_RS05535 (Sp14A_11570)	topA	1043670..1045820 (+)	2151	WP_115130240.1	type I DNA topoisomerase	-
Sp14A_RS05540 (Sp14A_11580)	-	1046135..1047127 (+)	993	WP_115130241.1	D-2-hydroxyacid dehydrogenase	-
Sp14A_RS05545 (Sp14A_11590)	-	1047257..1047925 (+)	669	WP_115130242.1	SatD family protein	-

Sequence

Protein

• Length: 280 a.a.
• Molecular weight: 31135.98 Da
• Isoelectric Point: 7.6337

>NTDB_id=241053 Sp14A_RS05530 WP_104967818.1 1042705..1043547(+) (dprA) [Streptococcus pluranimalium strain 14A0014]
MNNFELYKLKKAGLSNQHILNILDYEAKYQKSLSLRDRAVVSKCSNPVVFMEHYKNLDSKTLRQEFLTFPSISILDDDYP
LELKEIYNPPVLLFYKGNIDLLEKPKLAVVGARKCSEIGTKSIQKIITELENRFVIVSGLARGIDTAAHLSALKNGGASI
GIIGTGLDVYYPKENQRLQDFMMQNHLVLSEYGPGEQPLKYHFPERNRIIAGLCQGIIVAEAKLRSGSLITCERALEGGR
DVFALPGNILDGKSAGCLQLIQEGAKCITSGFDVLSDYSF

Nucleotide

• Length: 843 bp

>NTDB_id=241053 Sp14A_RS05530 WP_104967818.1 1042705..1043547(+) (dprA) [Streptococcus pluranimalium strain 14A0014]
ATGAATAATTTTGAATTGTACAAACTAAAAAAAGCAGGTTTATCTAATCAGCATATCTTAAATATCCTAGATTACGAAGC
TAAATATCAAAAATCCTTATCCCTTAGAGACCGTGCAGTAGTATCTAAATGTTCTAATCCAGTTGTTTTTATGGAGCATT
ATAAAAACTTGGATAGTAAGACCTTACGTCAAGAATTTCTAACCTTTCCTAGCATTTCCATCTTAGATGATGATTATCCT
TTGGAACTCAAGGAAATCTATAATCCACCTGTACTTTTGTTTTATAAAGGAAATATTGATCTGCTTGAAAAACCAAAACT
AGCAGTGGTTGGTGCTAGAAAATGTAGTGAGATAGGGACAAAGTCTATTCAGAAGATTATCACGGAACTGGAGAATCGTT
TTGTGATTGTTAGCGGATTGGCGCGTGGTATTGATACGGCAGCTCATTTGTCTGCACTTAAAAATGGAGGAGCTAGTATT
GGGATTATTGGAACAGGTCTTGATGTTTACTATCCCAAAGAAAATCAACGGTTACAGGATTTTATGATGCAAAACCATTT
GGTCCTTTCAGAGTATGGTCCTGGTGAACAACCACTTAAATATCACTTTCCAGAGCGAAATCGTATTATTGCAGGCCTTT
GTCAGGGAATTATTGTCGCTGAAGCTAAATTGCGCTCAGGAAGTTTAATCACTTGTGAGCGCGCATTAGAAGGAGGGAGA
GATGTTTTTGCACTTCCGGGCAATATTTTAGATGGCAAGTCCGCTGGTTGTTTACAATTGATTCAAGAGGGTGCAAAGTG
CATTACATCGGGATTTGATGTCTTGAGTGATTACTCATTTTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (72-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

3D structure

• AlphaFold DB: A0A2L0D4I4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	71.786	100	0.718
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	66.071	100	0.661
dprA/cilB/dalA	Streptococcus pneumoniae D39	66.071	100	0.661
dprA/cilB/dalA	Streptococcus pneumoniae R6	66.071	100	0.661
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	66.071	100	0.661
dprA/cilB/dalA	Streptococcus mitis SK321	66.071	100	0.661
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	65.714	100	0.657
dprA	Lactococcus lactis subsp. cremoris KW2	57.5	100	0.575
dprA	Legionella pneumophila strain ERS1305867	42.437	85	0.361